ATE139431T1 - Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri - Google Patents

Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri

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Publication number
ATE139431T1
ATE139431T1 AT89909342T AT89909342T ATE139431T1 AT E139431 T1 ATE139431 T1 AT E139431T1 AT 89909342 T AT89909342 T AT 89909342T AT 89909342 T AT89909342 T AT 89909342T AT E139431 T1 ATE139431 T1 AT E139431T1
Authority
AT
Austria
Prior art keywords
endocytosis
receptor
contrast agent
type mri
induced contrast
Prior art date
Application number
AT89909342T
Other languages
English (en)
Inventor
Edward T Menz
Jeffrey M Rothenberg
Ernest V Groman
Lee Josephson
Original Assignee
Advanced Magnetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Magnetics Inc filed Critical Advanced Magnetics Inc
Application granted granted Critical
Publication of ATE139431T1 publication Critical patent/ATE139431T1/de

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT89909342T 1988-08-04 1989-08-03 Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri ATE139431T1 (de)

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WO1990001295A1 (en) 1990-02-22
EP0381742A4 (en) 1991-04-24
EP0381742B1 (de) 1996-06-19
DE68926708D1 (de) 1996-07-25
JPH04501218A (ja) 1992-03-05
DE68926708T2 (de) 1996-10-31
EP0381742A1 (de) 1990-08-16
EP0670167A1 (de) 1995-09-06

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