ES2106010T3 - Sistemas de ensayo que comprenden equivalentes de tejido. - Google Patents

Sistemas de ensayo que comprenden equivalentes de tejido.

Info

Publication number
ES2106010T3
ES2106010T3 ES88302953T ES88302953T ES2106010T3 ES 2106010 T3 ES2106010 T3 ES 2106010T3 ES 88302953 T ES88302953 T ES 88302953T ES 88302953 T ES88302953 T ES 88302953T ES 2106010 T3 ES2106010 T3 ES 2106010T3
Authority
ES
Spain
Prior art keywords
tissue
systems including
test systems
including tissue
limited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88302953T
Other languages
English (en)
Inventor
Eugene Bell
Crispin Weinburg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organogenesis Inc
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2106010(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Application granted granted Critical
Publication of ES2106010T3 publication Critical patent/ES2106010T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA METODOS, APARATOS Y KITS PARA DETERMINAR LA INTERACCION DE TEJIDOS Y POR LO MENOS UN AGENTE MEDIANTE EL EMPLEO DE AL MENOS UN EQUIVALENTE TISULAR. EL EQUIVALENTE TISULAR INCLUYE, PERO NO SE LIMITA A, EQUIVALENTES DE TEJIDO EPITELIAL, TEJIDO CONJUNTIVO, CARTILAGO, HUESOS, SANGRE, ORGANOS, GLANDULAS Y VASOS SANGUINEOS, QUE COMPONEN DE CELULAS VIVAS Y MOLEUCLAS DE MATRIZ EXTRACELULARE, PRINCIPALMENTE COLAGENO. LOS AGENTES INCLUYEN, PERO NO SE LIMITAN A, DIVERSAS SUSTANCIAS TALES COMO PRODUCTOS QUIMICOS, COSMETICOS, PRODUCTOS FARMACEUTICOS, ESTIMULOS (POR EJEMPLO LUZ O DAÑO FISICO); Y AGENTES PROTECTORES DE TEJIDOS.
ES88302953T 1987-03-31 1988-03-31 Sistemas de ensayo que comprenden equivalentes de tejido. Expired - Lifetime ES2106010T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/032,848 US4835102A (en) 1987-03-31 1987-03-31 Tissue equivalent test systems

Publications (1)

Publication Number Publication Date
ES2106010T3 true ES2106010T3 (es) 1997-11-01

Family

ID=21867144

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88302953T Expired - Lifetime ES2106010T3 (es) 1987-03-31 1988-03-31 Sistemas de ensayo que comprenden equivalentes de tejido.

Country Status (9)

Country Link
US (1) US4835102A (es)
EP (1) EP0295762B1 (es)
JP (1) JP2767803B2 (es)
AT (1) ATE156915T1 (es)
CA (1) CA1305913C (es)
DE (1) DE3855991T2 (es)
ES (1) ES2106010T3 (es)
GR (1) GR3025046T3 (es)
IL (1) IL85599A (es)

Families Citing this family (76)

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US5510254A (en) * 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5053340A (en) * 1989-02-24 1991-10-01 National Testing Corporation In vitro test for dermal toxic properties
US5175092A (en) * 1989-05-04 1992-12-29 Millipore Corporation Vitro toxicology kit and method therefor
DE3923279A1 (de) * 1989-07-14 1990-01-18 Will W Prof Dr Minuth Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren
US5106949A (en) * 1989-09-15 1992-04-21 Organogenesis, Inc. Collagen compositions and methods for preparation thereof
IL95429A (en) * 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
JPH0747043B2 (ja) * 1990-04-24 1995-05-24 エイゼンバーグ，マーク 合成生体皮膚等価物
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US5612188A (en) * 1991-11-25 1997-03-18 Cornell Research Foundation, Inc. Automated, multicompartmental cell culture system
AU3603693A (en) * 1992-02-04 1993-09-01 Ohmicron Corporation Immunological analogs for captan
WO1993017336A1 (en) * 1992-02-19 1993-09-02 The Procter & Gamble Company In vitro model for eye and skin irritation testing
US5478739A (en) * 1992-10-23 1995-12-26 Advanced Tissue Sciences, Inc. Three-dimensional stromal cell and tissue culture system
US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
US5585265A (en) * 1992-11-30 1996-12-17 Gillette Company Human corneal epithelial cell lines with extended lifespan
US5656492A (en) * 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
WO1995011989A1 (en) * 1993-10-29 1995-05-04 Invitro International In vitro fluid toxicity bioassay
WO1995014221A1 (en) * 1993-11-18 1995-05-26 Ramsay Hospital Holdings Pty. Ltd. Processing cassette for tissue samples
US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
JPH09510108A (ja) * 1994-03-14 1997-10-14 クリオライフ，インコーポレイティド 移植用処理組織及び調製方法
EP1217101B8 (en) 1994-04-29 2006-02-01 Boston Scientific Scimed, Inc. Stent with collagen
JP2858087B2 (ja) * 1994-09-19 1999-02-17 グンゼ株式会社 組織培養用基材及び組織培養法
US6057137A (en) 1994-10-06 2000-05-02 Regents Of The University Of Minnesota Tissue-equivalent rods containing aligned collagen fibrils and schwann cells
US5948654A (en) 1996-08-28 1999-09-07 Univ Minnesota Magnetically oriented tissue-equivalent and biopolymer tubes comprising collagen
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
US5814328A (en) 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US5846188A (en) * 1997-01-17 1998-12-08 Palti; Yoram Sensor utilizing living muscle cells
AU744809B2 (en) 1997-03-11 2002-03-07 Pola Chemical Industries Inc. Method for evaluating skin conditioning agents and process for producing external skin preparations
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6066495A (en) * 1998-03-05 2000-05-23 Tissue Engineering, Inc. Methods and apparatus for the conditioning of ligament replacement tissue
AU3077299A (en) 1998-03-11 1999-09-27 University Of Southern California Method of promoting production of living tissue equivalents
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US6293970B1 (en) 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US7063726B2 (en) * 1998-06-30 2006-06-20 Lifenet Plasticized bone grafts and methods of making and using same
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
US8563232B2 (en) * 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
AT407047B (de) * 1998-08-03 2000-11-27 Pfaller Walter Dr Zellkulturvorrichtung
JP2002530069A (ja) 1998-11-19 2002-09-17 オルガノジェネシス インク． 生物工学的組織構築物およびそれを生成および使用する方法
US6030789A (en) * 1999-03-10 2000-02-29 The Gillette Company Human conjunctival epithelial cell lines with an extended life span
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
WO2001092476A2 (de) * 2000-05-31 2001-12-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. In vitro-gewebetestsystem
US6852526B2 (en) * 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
EP1301619B1 (en) * 2000-07-14 2006-10-18 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
US7172859B2 (en) * 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
US20080182293A1 (en) * 2000-07-14 2008-07-31 Transform Pharmaceuticals, Inc. Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
US7544465B2 (en) * 2001-09-27 2009-06-09 The Wistar Institute Methods and compositions for monitoring cell migration and identifying clinically relevant cytotoxic T lymphocyte activity
WO2003041568A2 (en) * 2001-11-15 2003-05-22 University Of Medicine & Dentistry Of New Jersey A three-dimensional matrix for producing living tissue equivalents
WO2003089566A1 (en) * 2002-04-22 2003-10-30 Tufts University Multi-dimensional strain bioreactor
AUPS242702A0 (en) * 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US7229820B2 (en) 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
EP1534345A4 (en) * 2002-07-12 2012-03-21 Yissum Res Dev Co METHOD AND DEVICE FOR INDUCING BIOLOGICAL PROCESSES WITH MICROORGANISMS
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US20040185430A1 (en) * 2002-12-20 2004-09-23 Marc Andre Lefebvre Process for evaluating the cosmetic or dermatological activity of a product and use of plant material
US20090024224A1 (en) 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
CN101918532B (zh) * 2007-08-22 2016-03-30 普罗柏欧贞股份公司 用于体外测试免疫原性和免疫功能的培养系统和方法
JP5579620B2 (ja) * 2008-01-10 2014-08-27 ヒューレル コーポレーション 免疫システムモデリング・デバイスおよび方法
CN107988072B (zh) 2008-07-16 2022-11-29 儿童医疗中心有限公司 具有微通道的器官模仿装置及其使用和制造方法
ES2750303T3 (es) * 2010-04-05 2020-03-25 Emd Millipore Corp Membranas poliméricas con propiedades de permeabilidad similares a la piel humana y usos de las mismas
RU2612915C2 (ru) 2011-02-28 2017-03-13 Президент Энд Феллоуз Ов Харвард Колледж Система культивирования клеток
WO2013086486A1 (en) 2011-12-09 2013-06-13 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2725094A1 (en) * 2012-10-29 2014-04-30 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Epithelial tissue model
US9855554B2 (en) 2013-07-22 2018-01-02 President And Fellows Of Harvard College Microfluidic cartridge assembly
AU2014386209B2 (en) 2013-12-20 2021-03-11 President And Fellows Of Harvard College Low shear microfluidic devices and methods of use and manufacturing thereof
GB2581749B (en) 2013-12-20 2021-03-03 Harvard College Organomimetic devices and methods of use and manufacturing thereof
WO2016010861A1 (en) 2014-07-14 2016-01-21 President And Fellows Of Harvard College Systems and methods for improved performance of fluidic and microfluidic systems
WO2017019542A1 (en) 2015-07-24 2017-02-02 President And Fellows Of Harvard College Radial microfluidic devices and methods of use
CA3036378A1 (en) 2016-09-13 2018-03-22 President And Fellows Of Harvard College Methods relating to intestinal organ-on-a-chip
CN112980690B (zh) * 2019-12-17 2022-10-21 华东数字医学工程研究院 Pdx模型孵育装置和抗肿瘤药物筛选方法
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JPS6110136A (ja) * 1984-06-25 1986-01-17 Fumio Itatsu 油圧機器の圧力調整装置
JPS6133593A (ja) * 1984-07-26 1986-02-17 株式会社東芝 防犯装置
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US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
US4760020A (en) * 1985-05-03 1988-07-26 Eye Research Institute Of Retina Foundation Method for testing biocompatibility

Also Published As

Publication number Publication date
EP0295762A2 (en) 1988-12-21
DE3855991T2 (de) 1998-01-22
GR3025046T3 (en) 1998-01-30
JPS63296699A (ja) 1988-12-02
CA1305913C (en) 1992-08-04
DE3855991D1 (de) 1997-09-18
IL85599A (en) 1991-11-21
IL85599A0 (en) 1988-08-31
EP0295762A3 (en) 1990-07-04
EP0295762B1 (en) 1997-08-13
ATE156915T1 (de) 1997-08-15
US4835102A (en) 1989-05-30
JP2767803B2 (ja) 1998-06-18

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