ATE139702T1 - Die freisetzung des histamin hemmenden faktors sowie diesen enthaltende präparate - Google Patents
Die freisetzung des histamin hemmenden faktors sowie diesen enthaltende präparateInfo
- Publication number
- ATE139702T1 ATE139702T1 AT89901783T AT89901783T ATE139702T1 AT E139702 T1 ATE139702 T1 AT E139702T1 AT 89901783 T AT89901783 T AT 89901783T AT 89901783 T AT89901783 T AT 89901783T AT E139702 T1 ATE139702 T1 AT E139702T1
- Authority
- AT
- Austria
- Prior art keywords
- hrif
- treatment
- methods
- cell lines
- release
- Prior art date
Links
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title abstract 6
- 229960001340 histamine Drugs 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 102000004127 Cytokines Human genes 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 102000005348 Neuraminidase Human genes 0.000 abstract 1
- 108010006232 Neuraminidase Proteins 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 210000003651 basophil Anatomy 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000002270 exclusion chromatography Methods 0.000 abstract 1
- 210000003630 histaminocyte Anatomy 0.000 abstract 1
- 238000004255 ion exchange chromatography Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0642—Granulocytes, e.g. basopils, eosinophils, neutrophils, mast cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14309488A | 1988-01-12 | 1988-01-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE139702T1 true ATE139702T1 (de) | 1996-07-15 |
Family
ID=22502579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89901783T ATE139702T1 (de) | 1988-01-12 | 1989-01-11 | Die freisetzung des histamin hemmenden faktors sowie diesen enthaltende präparate |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0398924B1 (de) |
| AT (1) | ATE139702T1 (de) |
| AU (1) | AU2947889A (de) |
| CA (1) | CA1334652C (de) |
| DE (1) | DE68926743T2 (de) |
| WO (1) | WO1989006545A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06502396A (ja) * | 1990-07-25 | 1994-03-17 | ボード、オブ、リージェンツ、ザ、ユニバーシティー、オブ、テキサス、システム | 好塩基球からのサイトカイン誘導ヒスタミン放出のインターロイキン8阻害 |
| ES2249863T3 (es) * | 1995-02-27 | 2006-04-01 | Gilead Sciences, Inc. | Inhibidores selectivos de neuraminidasa viral o bacteriana. |
| CN112899228B (zh) * | 2021-02-04 | 2022-09-23 | 广州医科大学附属第一医院 | 一种从支气管肺泡灌洗液中分离提取细胞的方法 |
-
1989
- 1989-01-11 AT AT89901783T patent/ATE139702T1/de not_active IP Right Cessation
- 1989-01-11 WO PCT/US1989/000104 patent/WO1989006545A1/en not_active Ceased
- 1989-01-11 AU AU29478/89A patent/AU2947889A/en not_active Abandoned
- 1989-01-11 DE DE68926743T patent/DE68926743T2/de not_active Expired - Fee Related
- 1989-01-11 EP EP89901783A patent/EP0398924B1/de not_active Expired - Lifetime
- 1989-01-12 CA CA000588069A patent/CA1334652C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0398924A1 (de) | 1990-11-28 |
| CA1334652C (en) | 1995-03-07 |
| WO1989006545A1 (en) | 1989-07-27 |
| DE68926743T2 (de) | 1997-01-09 |
| DE68926743D1 (de) | 1996-08-01 |
| EP0398924B1 (de) | 1996-06-26 |
| AU2947889A (en) | 1989-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |