ATE140600T1 - Endoskopisches bilderzeugungssystem für erkranktes gewebe - Google Patents

Endoskopisches bilderzeugungssystem für erkranktes gewebe

Info

Publication number
ATE140600T1
ATE140600T1 AT92850098T AT92850098T ATE140600T1 AT E140600 T1 ATE140600 T1 AT E140600T1 AT 92850098 T AT92850098 T AT 92850098T AT 92850098 T AT92850098 T AT 92850098T AT E140600 T1 ATE140600 T1 AT E140600T1
Authority
AT
Austria
Prior art keywords
tissue
autofluorescence
light
abnormal
filtered
Prior art date
Application number
AT92850098T
Other languages
English (en)
Inventor
Branko Palcic
Bruno Jaggi
Amedeus Edward Profio
Calum Macaulay
Stephen Lam
Jaclyn Hung
Original Assignee
Xillix Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25674604&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE140600(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xillix Technologies Corp filed Critical Xillix Technologies Corp
Application granted granted Critical
Publication of ATE140600T1 publication Critical patent/ATE140600T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/042—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0646—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with illumination filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/063—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for monochromatic or narrow-band illumination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Surgical Instruments (AREA)
AT92850098T 1991-05-08 1992-05-05 Endoskopisches bilderzeugungssystem für erkranktes gewebe ATE140600T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002042075A CA2042075C (en) 1991-05-08 1991-05-08 Endoscopic imaging system
US08/428,494 US5507287A (en) 1991-05-08 1995-04-27 Endoscopic imaging system for diseased tissue

Publications (1)

Publication Number Publication Date
ATE140600T1 true ATE140600T1 (de) 1996-08-15

Family

ID=25674604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92850098T ATE140600T1 (de) 1991-05-08 1992-05-05 Endoskopisches bilderzeugungssystem für erkranktes gewebe

Country Status (6)

Country Link
US (1) US5507287A (de)
EP (1) EP0512965B1 (de)
JP (1) JP3317409B2 (de)
AT (1) ATE140600T1 (de)
CA (1) CA2042075C (de)
DE (1) DE69212382T2 (de)

Families Citing this family (251)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6196226B1 (en) 1990-08-10 2001-03-06 University Of Washington Methods and apparatus for optically imaging neuronal tissue and activity
US5769792A (en) * 1991-07-03 1998-06-23 Xillix Technologies Corp. Endoscopic imaging system for diseased tissue
US5352613A (en) * 1993-10-07 1994-10-04 Tafas Triantafillos P Cytological screening method
US6136540A (en) * 1994-10-03 2000-10-24 Ikonisys Inc. Automated fluorescence in situ hybridization detection of genetic abnormalities
FR2717365B1 (fr) * 1994-03-21 1996-05-15 Rech Biolog Et Dispositif d'imagerie endoscopique ou fibroscopique en fluorescence dans l'infrarouge.
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5782770A (en) * 1994-05-12 1998-07-21 Science Applications International Corporation Hyperspectral imaging methods and apparatus for non-invasive diagnosis of tissue for cancer
DE4420599A1 (de) * 1994-06-13 1995-12-14 Siemens Ag Gerät zur Untersuchung von Gewebe in vivo
DE19535114B4 (de) * 1994-09-21 2013-09-05 Hoya Corp. Endoskopsystem mit Fluoreszenzdiagnose
JP3411737B2 (ja) * 1995-03-03 2003-06-03 ペンタックス株式会社 生体の蛍光診断装置
US6258576B1 (en) 1996-06-19 2001-07-10 Board Of Regents, The University Of Texas System Diagnostic method and apparatus for cervical squamous intraepithelial lesions in vitro and in vivo using fluorescence spectroscopy
US5991653A (en) * 1995-03-14 1999-11-23 Board Of Regents, The University Of Texas System Near-infrared raman spectroscopy for in vitro and in vivo detection of cervical precancers
AU6334896A (en) * 1995-06-07 1996-12-30 Gabriel Medical, Inc. Imaging system with independent processing of visible and in frared light energy
US6032070A (en) * 1995-06-07 2000-02-29 University Of Arkansas Method and apparatus for detecting electro-magnetic reflection from biological tissue
US5910816A (en) * 1995-06-07 1999-06-08 Stryker Corporation Imaging system with independent processing of visible an infrared light energy
US7328059B2 (en) * 1996-08-23 2008-02-05 The Texas A & M University System Imaging of light scattering tissues with fluorescent contrast agents
WO1997008538A1 (en) * 1995-08-24 1997-03-06 Purdue Research Foundation Fluorescence lifetime-based imaging and spectroscopy in tissues and other random media
US5930732A (en) * 1995-09-15 1999-07-27 Accumed International, Inc. System for simplifying the implementation of specified functions
US6091842A (en) * 1996-10-25 2000-07-18 Accumed International, Inc. Cytological specimen analysis system with slide mapping and generation of viewing path information
US6118581A (en) * 1995-09-15 2000-09-12 Accumed International, Inc. Multifunctional control unit for a microscope
US6148096A (en) * 1995-09-15 2000-11-14 Accumed International, Inc. Specimen preview and inspection system
US20040052730A1 (en) * 1995-10-04 2004-03-18 Cytoscan Sciences, L.L.C. Methods and systems for assessing biological materials using optical and spectroscopic detection techniques
US6096510A (en) * 1995-10-04 2000-08-01 Cytoscan Sciences, Llc Methods and systems for assessing biological materials using optical detection techniques
US6573063B2 (en) 1995-10-04 2003-06-03 Cytoscan Sciences, Llc Methods and systems for assessing biological materials using optical and spectroscopic detection techniques
JP3435268B2 (ja) * 1995-11-09 2003-08-11 ペンタックス株式会社 蛍光観察内視鏡装置
US5953477A (en) * 1995-11-20 1999-09-14 Visionex, Inc. Method and apparatus for improved fiber optic light management
US6174424B1 (en) 1995-11-20 2001-01-16 Cirrex Corp. Couplers for optical fibers
US5804389A (en) * 1995-12-29 1998-09-08 Phanos Technologies, Inc. Method for detecting abnormal epithelial cell shedding
US5647368A (en) * 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
US6571119B2 (en) 1996-03-06 2003-05-27 Fuji Photo Film Co., Ltd. Fluorescence detecting apparatus
JP3796635B2 (ja) * 1996-03-06 2006-07-12 富士写真フイルム株式会社 蛍光検出装置
DE19612536A1 (de) * 1996-03-29 1997-10-02 Freitag Lutz Dr Anordnung und Verfahren zur Diagnose von malignem Gewebe durch Fluoreszenzbetrachtung
IL126659A (en) * 1996-04-19 2003-05-29 Dow Global Technologies Inc Fluorescent chelates as visual tissue specific imaging agents
JP3552844B2 (ja) * 1996-04-30 2004-08-11 富士写真フイルム株式会社 内視鏡
DE19626433A1 (de) * 1996-06-19 1998-01-15 Jan Henrik Dr Wilkens Endoskopkopf
US5842995A (en) * 1996-06-28 1998-12-01 Board Of Regents, The Univerisity Of Texas System Spectroscopic probe for in vivo measurement of raman signals
DE19631575C1 (de) * 1996-07-26 1999-02-04 Werner Dr Schramm Anordnung zur Überwachung eines Feten während der Geburt
US6293911B1 (en) * 1996-11-20 2001-09-25 Olympus Optical Co., Ltd. Fluorescent endoscope system enabling simultaneous normal light observation and fluorescence observation in infrared spectrum
US7179222B2 (en) * 1996-11-20 2007-02-20 Olympus Corporation Fluorescent endoscope system enabling simultaneous achievement of normal light observation based on reflected light and fluorescence observation based on light with wavelengths in infrared spectrum
US6135965A (en) * 1996-12-02 2000-10-24 Board Of Regents, The University Of Texas System Spectroscopic detection of cervical pre-cancer using radial basis function networks
CA2192036A1 (en) * 1996-12-04 1998-06-04 Harvey Lui Fluorescence scope system for dermatologic diagnosis
US7865230B1 (en) 1997-02-07 2011-01-04 Texas A&M University System Method and system for detecting sentinel lymph nodes
JP3654325B2 (ja) * 1997-02-13 2005-06-02 富士写真フイルム株式会社 蛍光検出装置
US5919135A (en) * 1997-02-28 1999-07-06 Lemelson; Jerome System and method for treating cellular disorders in a living being
US6059720A (en) * 1997-03-07 2000-05-09 Asahi Kogaku Kogyo Kabushiki Kaisha Endoscope system with amplification of fluorescent image
US6208783B1 (en) 1997-03-13 2001-03-27 Cirrex Corp. Optical filtering device
CA2283949A1 (en) 1997-03-13 1998-09-17 Haishan Zeng Methods and apparatus for detecting the rejection of transplanted tissue
US6008889A (en) * 1997-04-16 1999-12-28 Zeng; Haishan Spectrometer system for diagnosis of skin disease
US5999844A (en) * 1997-04-23 1999-12-07 Accumed International, Inc. Method and apparatus for imaging and sampling diseased tissue using autofluorescence
US6081740A (en) * 1997-04-23 2000-06-27 Accumed International, Inc. Method and apparatus for imaging and sampling diseased tissue
JP3417795B2 (ja) * 1997-04-30 2003-06-16 ペンタックス株式会社 蛍光診断装置
EP0889307B1 (de) * 1997-07-01 2003-09-03 OptoMed Optomedical Systems GmbH Bildgebendes Spektrometer
US5986271A (en) * 1997-07-03 1999-11-16 Lazarev; Victor Fluorescence imaging system
US6124597A (en) 1997-07-07 2000-09-26 Cedars-Sinai Medical Center Method and devices for laser induced fluorescence attenuation spectroscopy
US5921926A (en) * 1997-07-28 1999-07-13 University Of Central Florida Three dimensional optical imaging colposcopy
US6405074B1 (en) 1997-08-29 2002-06-11 Bhaskar Banerjee Detection of cancer using cellular autofluorescence
US6393315B1 (en) 1997-09-12 2002-05-21 Communaute Europeenne Detecting and mapping of inflamed zones in a living tissue
JPH1189789A (ja) * 1997-09-24 1999-04-06 Olympus Optical Co Ltd 蛍光画像装置
US6422994B1 (en) 1997-09-24 2002-07-23 Olympus Optical Co., Ltd. Fluorescent diagnostic system and method providing color discrimination enhancement
US6937885B1 (en) 1997-10-30 2005-08-30 Hypermed, Inc. Multispectral/hyperspectral medical instrument
DE19854833B4 (de) 1997-11-27 2009-06-04 Hoya Corp. Fluoreszenzdiagnoseeinrichtung
US6055451A (en) 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
US20030135122A1 (en) * 1997-12-12 2003-07-17 Spectrx, Inc. Multi-modal optical tissue diagnostic system
WO2000015101A1 (en) * 1998-09-11 2000-03-23 Spectrx, Inc. Multi-modal optical tissue diagnostic system
DE19800312A1 (de) 1998-01-07 1999-07-08 Wolf Gmbh Richard Diagnosegerät zur bildgebenden Aufnahme fluoreszierender biologischer Gewebebereiche
DE19804797A1 (de) 1998-02-07 1999-08-12 Storz Karl Gmbh & Co Vorrichtung zur endoskopischen Fluoreszenzdiagnose von Gewebe
US6066102A (en) * 1998-03-09 2000-05-23 Spectrascience, Inc. Optical biopsy forceps system and method of diagnosing tissue
US6174291B1 (en) * 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
US6462770B1 (en) 1998-04-20 2002-10-08 Xillix Technologies Corp. Imaging system with automatic gain control for reflectance and fluorescence endoscopy
US6834238B1 (en) 1998-06-08 2004-12-21 Cytoscan Sciences Llc Method for identifying optical contrast enhancing agents
EP1087698A4 (de) * 1998-06-16 2003-09-03 Bhaskar Banerjee Krebserkennung mittels zellulärer autofluoreszens
US6405070B1 (en) 1998-06-16 2002-06-11 Bhaskar Banerjee Detection of cancer using cellular autofluorescence
US6110106A (en) * 1998-06-24 2000-08-29 Biomax Technologies, Inc. Endoscopes and methods relating to direct viewing of a target tissue
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
EP1161178A2 (de) * 1998-12-23 2001-12-12 Medispectra Inc. Systeme und verfahren zur optischen untersuchung von proben
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
EP1148810B1 (de) * 1999-01-26 2005-11-16 Newton Laboratories, Inc. Vorrichtung zur autofluoreszensbildgebung für ein endoskop
US6584342B1 (en) * 1999-02-12 2003-06-24 Alexei I. Trushin Method for diagnosing proliferation regions and device for realizing the same
US6580935B1 (en) 1999-03-12 2003-06-17 Cirrex Corp. Method and system for stabilizing reflected light
US20040147843A1 (en) * 1999-11-05 2004-07-29 Shabbir Bambot System and method for determining tissue characteristics
US6697666B1 (en) 1999-06-22 2004-02-24 Board Of Regents, The University Of Texas System Apparatus for the characterization of tissue of epithelial lined viscus
JP2001078175A (ja) 1999-07-07 2001-03-23 Fuji Photo Film Co Ltd 蛍光観察装置
JP2001017379A (ja) 1999-07-09 2001-01-23 Fuji Photo Film Co Ltd 蛍光診断装置
US20050182434A1 (en) * 2000-08-11 2005-08-18 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
DK1143852T3 (da) * 1999-09-24 2007-11-26 Ca Nat Research Council Anordning til udförelse af intraoperativ angiografi
US6915154B1 (en) 1999-09-24 2005-07-05 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
EP1089067B1 (de) * 1999-09-29 2004-12-08 Fuji Photo Film Co., Ltd. Vorrichtung zur Erfassung eines Fluoreszenzbildes
US7054002B1 (en) 1999-10-08 2006-05-30 The Texas A&M University System Characterization of luminescence in a scattering medium
US6603552B1 (en) * 1999-12-22 2003-08-05 Xillix Technologies Corp. Portable system for detecting skin abnormalities based on characteristic autofluorescence
EP1239771B1 (de) 1999-12-22 2004-10-06 Xillix Technologies Corp. Tragbares system zur ermittlung von hautanomalien
AU779659B2 (en) 2000-02-08 2005-02-03 Cornell Research Foundation Inc. Multiphoton excitation through optical fibers for fluorescence spectroscopy
US6468203B2 (en) 2000-04-03 2002-10-22 Neoguide Systems, Inc. Steerable endoscope and improved method of insertion
US6858005B2 (en) 2000-04-03 2005-02-22 Neo Guide Systems, Inc. Tendon-driven endoscope and methods of insertion
US8888688B2 (en) 2000-04-03 2014-11-18 Intuitive Surgical Operations, Inc. Connector device for a controllable instrument
US8517923B2 (en) 2000-04-03 2013-08-27 Intuitive Surgical Operations, Inc. Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities
US6984203B2 (en) * 2000-04-03 2006-01-10 Neoguide Systems, Inc. Endoscope with adjacently positioned guiding apparatus
US6610007B2 (en) * 2000-04-03 2003-08-26 Neoguide Systems, Inc. Steerable segmented endoscope and method of insertion
ATE346540T1 (de) * 2000-05-19 2006-12-15 Coherent Gmbh Vorrichtung und verfahren zur erkennung von tumorösem gewebe
DE60122894T2 (de) 2000-07-14 2007-03-15 Xillix Technologies Corp., Richmond Kompaktes fluorezenz endoskopisches video system
JP2002045329A (ja) * 2000-08-01 2002-02-12 Fuji Photo Film Co Ltd 蛍光画像表示装置
JP2004518488A (ja) 2000-11-02 2004-06-24 コーネル リサーチ ファンデーション インコーポレーテッド インビボ多光子診断的な神経変性疾患の検出および撮像
US6826424B1 (en) 2000-12-19 2004-11-30 Haishan Zeng Methods and apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices
US6529769B2 (en) 2001-03-08 2003-03-04 Apti, Inc. Apparatus for performing hyperspectral endoscopy
US20040038320A1 (en) * 2001-03-09 2004-02-26 Bhaskar Banerjee Methods of detecting cancer using cellular autofluorescence
US6600947B2 (en) 2001-03-16 2003-07-29 Nymox Corporation Method of detecting amyloid-containing lesions by autofluorescence
AU2002306790B2 (en) 2001-03-19 2007-05-24 Ikonisys, Inc. Epifluorescence microscope with improved image contrast
JP4259879B2 (ja) 2001-05-17 2009-04-30 ゼノジェン コーポレイション 身体領域内の標的の深さ、輝度およびサイズを決定するための方法および装置
US7217266B2 (en) * 2001-05-30 2007-05-15 Anderson R Rox Apparatus and method for laser treatment with spectroscopic feedback
DE10136191A1 (de) * 2001-07-25 2003-02-20 Wolf Gmbh Richard Vorrichtung zur bildgebenden und spektroskopischen Diagnose von Gewebe
JP2005514145A (ja) 2002-01-09 2005-05-19 ネオガイド システムズ， インコーポレイテッド 内視鏡結腸切除のための装置および方法
AU2002360767A1 (en) * 2002-01-09 2003-07-30 Neoguide Systems, Inc Apparatus and method for spectroscopic examination of the colon
US20060241496A1 (en) 2002-01-15 2006-10-26 Xillix Technologies Corp. Filter for use with imaging endoscopes
US6899675B2 (en) 2002-01-15 2005-05-31 Xillix Technologies Corp. Fluorescence endoscopy video systems with no moving parts in the camera
US20030216626A1 (en) * 2002-03-28 2003-11-20 Fuji Photo Film Co., Ltd. Fluorescence judging method and apparatus
JP4109133B2 (ja) * 2002-03-28 2008-07-02 富士フイルム株式会社 蛍光判定装置
US8131332B2 (en) * 2002-04-04 2012-03-06 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence of various sites
CN100405976C (zh) * 2002-04-14 2008-07-30 王念勇 利用固有荧光诊断早期肿瘤的诊断仪
CN1474175B (zh) * 2002-04-15 2010-05-26 黄鹰 超精细光谱成像仪或系统
JP4311607B2 (ja) 2002-05-27 2009-08-12 富士フイルム株式会社 蛍光診断情報生成方法および装置
US7257437B2 (en) * 2002-07-05 2007-08-14 The Regents Of The University Of California Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
DE10252313B9 (de) * 2002-11-11 2006-10-19 Carl Zeiss Untersuchungssystem zur gleichzeitigen direkten Sichtbarmachung einer Fluoreszenzmarkierung und eines die Fluoreszenzmarkierung umgebenden Gewebebereichs und Untersuchungsverfahren dafür
US7365844B2 (en) * 2002-12-10 2008-04-29 Board Of Regents, The University Of Texas System Vision enhancement system for improved detection of epithelial neoplasia and other conditions
JP2006509573A (ja) * 2002-12-13 2006-03-23 イエトメド リミテッド 手術中に腫瘍と正常組織とを実時間で区別するのに特に有用な光学的検査方法および装置
DE10305599A1 (de) * 2003-02-11 2004-08-26 Richard Wolf Gmbh Vorrichtung zur bildgebenden Diagnose von Gewebe
US8882657B2 (en) 2003-03-07 2014-11-11 Intuitive Surgical Operations, Inc. Instrument having radio frequency identification systems and methods for use
JP2006520638A (ja) * 2003-03-18 2006-09-14 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ 監視による構成要素の分析
US20040225222A1 (en) * 2003-05-08 2004-11-11 Haishan Zeng Real-time contemporaneous multimodal imaging and spectroscopy uses thereof
US7697975B2 (en) * 2003-06-03 2010-04-13 British Colombia Cancer Agency Methods and apparatus for fluorescence imaging using multiple excitation-emission pairs and simultaneous multi-channel image detection
EP1654531A1 (de) * 2003-06-20 2006-05-10 The Texas A & M University System Verfahren und system zum fluoreszenz-kontrastverstärkten abbilden im nahinfrarotbereich mit flächiger beleuchtung und flächiger detektion
FR2858205B1 (fr) * 2003-07-28 2005-09-16 Sopro Soc Appareil de detection et de caracterisation des tissus biologiques
CA2535843A1 (en) 2003-08-19 2005-06-23 Cornell Research Foundation, Inc. Optical fiber delivery and collection system for biological applications such as multiphoton microscopy, spectroscopy, and endoscopy
JP4306380B2 (ja) * 2003-09-10 2009-07-29 株式会社日立メディコ 医用画像表示方法及び装置
US7321791B2 (en) * 2003-09-23 2008-01-22 Cambridge Research And Instrumentation, Inc. Spectral imaging of deep tissue
US8634607B2 (en) 2003-09-23 2014-01-21 Cambridge Research & Instrumentation, Inc. Spectral imaging of biological samples
JP2005152130A (ja) * 2003-11-21 2005-06-16 Olympus Corp 内視鏡撮像システム
US7643869B1 (en) 2004-03-17 2010-01-05 Dabiri Ali E Apparatus for non-invasive cancerous tissue diagnosis and tomography using terahertz imaging
US8019413B2 (en) 2007-03-19 2011-09-13 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US20070244520A1 (en) * 2004-04-19 2007-10-18 Searete Llc Lumen-traveling biological interface device and method of use
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
WO2006005075A2 (en) * 2004-06-30 2006-01-12 Amir Belson Apparatus and methods for capsule endoscopy of the esophagus
US7218822B2 (en) * 2004-09-03 2007-05-15 Chemimage Corporation Method and apparatus for fiberscope
CN101026991A (zh) * 2004-09-28 2007-08-29 日拉制药有限公司 用于检测异常上皮组织的方法
US20060241501A1 (en) * 2004-09-28 2006-10-26 Zila Pharmaceuticals, Inc. Method and apparatus for detecting abnormal epithelial tissue
US20080255462A1 (en) * 2004-09-28 2008-10-16 Zila Pharmaceuticals, Inc. Light stick
US20070093802A1 (en) * 2005-10-21 2007-04-26 Danek Christopher J Energy delivery devices and methods
CN101151623B (zh) 2005-01-27 2010-06-23 剑桥研究和仪器设备股份有限公司 对样本图像的特征进行分类的方法和设备
US20060217594A1 (en) * 2005-03-24 2006-09-28 Ferguson Gary W Endoscopy device with removable tip
US20060235458A1 (en) * 2005-04-15 2006-10-19 Amir Belson Instruments having an external working channel
US20060239921A1 (en) 2005-04-26 2006-10-26 Novadaq Technologies Inc. Real time vascular imaging during solid organ transplant
WO2007002323A2 (en) * 2005-06-23 2007-01-04 Epoc, Inc. System and method for monitoring of end organ oxygenation by measurement of in vivo cellular energy status
DE102005036146A1 (de) * 2005-07-28 2007-02-08 Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. Anordnung zur optischen Flammenprüfung
US8451327B2 (en) 2005-08-18 2013-05-28 Hoya Corporation Electronic endoscope, endoscope light unit, endoscope processor, and electronic endoscope system
JP4681981B2 (ja) * 2005-08-18 2011-05-11 Ｈｏｙａ株式会社 電子内視鏡装置
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
WO2007033379A2 (en) * 2005-09-14 2007-03-22 Neoguide Systems, Inc. Methods and apparatus for performing transluminal and other procedures
WO2007050683A2 (en) * 2005-10-24 2007-05-03 Spectrascience, Inc. System and method for non-endoscopic optical biopsy detection of diseased tissue
EP3788944B1 (de) 2005-11-22 2024-02-28 Intuitive Surgical Operations, Inc. System zur bestimmung der form eines biegbaren instruments
JP2009517608A (ja) * 2005-11-23 2009-04-30 ネオガイド システムズ， インコーポレイテッド 操舵可能な装置用の非金属マルチストランド制御ケーブル
US20070191715A1 (en) * 2006-01-30 2007-08-16 Hiroyuki Yonekawa Method and device for the in vivo observation with embedded cell and tissue
US20090303317A1 (en) 2006-02-07 2009-12-10 Novadaq Technologies Inc. Near infrared imaging
US8562802B1 (en) 2006-02-13 2013-10-22 Life Technologies Corporation Transilluminator base and scanner for imaging fluorescent gels, charging devices and portable electrophoresis systems
KR100798486B1 (ko) * 2006-03-29 2008-01-28 한국전기연구원 형광 진단 및 광역동치료를 위한 광원장치
US20080058785A1 (en) * 2006-04-12 2008-03-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Autofluorescent imaging and target ablation
US20120035437A1 (en) 2006-04-12 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Navigation of a lumen traveling device toward a target
ATE534974T1 (de) * 2006-04-18 2011-12-15 Ge Healthcare Bio Sciences System zur vorbereitung eines bildes zur segmentierung
US8568299B2 (en) * 2006-05-19 2013-10-29 Intuitive Surgical Operations, Inc. Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope
US8163003B2 (en) * 2006-06-16 2012-04-24 The Invention Science Fund I, Llc Active blood vessel sleeve methods and systems
EP2051603B1 (de) 2006-07-28 2019-09-11 Novadaq Technologies ULC System und verfahren zur ablage und entfernung eines optischen elements auf bzw. von einem endoskopobjektiv
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
KR100853655B1 (ko) * 2006-12-15 2008-08-25 한국전기연구원 피부 질환의 광학 진단 및 치료를 위한 장치, 광원 시스템 및 장치의 이용방법
US8498695B2 (en) 2006-12-22 2013-07-30 Novadaq Technologies Inc. Imaging system with a single color image sensor for simultaneous fluorescence and color video endoscopy
US20080177140A1 (en) * 2007-01-23 2008-07-24 Xillix Technologies Corp. Cameras for fluorescence and reflectance imaging
DE102007014413B4 (de) * 2007-03-17 2016-02-04 DüRR DENTAL AG Verfahren zum Auswerten von Fluoreszenzbildsätzen und Vorrichtung zu seiner Durchführung
JP2008229024A (ja) 2007-03-20 2008-10-02 Olympus Corp 蛍光観察装置
JP2009000236A (ja) * 2007-06-20 2009-01-08 Olympus Medical Systems Corp 画像生成装置
US7641343B1 (en) 2007-07-26 2010-01-05 Motamedi Manouchehr E Method and apparatus for early diagnosis of Alzheimer's using non-invasive eye tomography by terahertz
US20090062662A1 (en) 2007-08-27 2009-03-05 Remicalm, Llc Optical spectroscopic device for the identification of cervical cancer
US9220398B2 (en) 2007-10-11 2015-12-29 Intuitive Surgical Operations, Inc. System for managing Bowden cables in articulating instruments
US20090099460A1 (en) * 2007-10-16 2009-04-16 Remicalm Llc Method and device for the optical spectroscopic identification of cervical cancer
US20100268025A1 (en) * 2007-11-09 2010-10-21 Amir Belson Apparatus and methods for capsule endoscopy of the esophagus
US20090192390A1 (en) * 2008-01-24 2009-07-30 Lifeguard Surgical Systems Common bile duct surgical imaging system
US9072445B2 (en) * 2008-01-24 2015-07-07 Lifeguard Surgical Systems Inc. Common bile duct surgical imaging system
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
KR101707924B1 (ko) 2008-02-06 2017-02-17 인튜어티브 서지컬 오퍼레이션즈 인코포레이티드 제동 능력을 가지고 있는 체절식 기구
US8182418B2 (en) 2008-02-25 2012-05-22 Intuitive Surgical Operations, Inc. Systems and methods for articulating an elongate body
US9173554B2 (en) 2008-03-18 2015-11-03 Novadaq Technologies, Inc. Imaging system for combined full-color reflectance and near-infrared imaging
US20090236541A1 (en) * 2008-03-24 2009-09-24 General Electric Company System and Methods for Optical Imaging
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
US8167793B2 (en) * 2008-04-26 2012-05-01 Intuitive Surgical Operations, Inc. Augmented stereoscopic visualization for a surgical robot using time duplexing
EP2285421B1 (de) 2008-05-02 2018-04-11 Novadaq Technologies ULC Verfahren zur herstellung und verwendung substanzbeladener erythrozyten zur beobachtung und behandlung von mikrovaskulärer hämodynamik
EP3501384B1 (de) 2008-05-20 2024-07-17 University Health Network Verfahren zur bildgebung und überwachung auf fluoreszenzbasis
DE102008034008B4 (de) * 2008-07-21 2010-07-01 Carl Zeiss Surgical Gmbh Filtersatz zur Beobachtung von Fluoreszenzstrahlung in biologischem Gewebe
US8939966B2 (en) * 2008-08-21 2015-01-27 University Of Florida Research Foundation, Inc. Differential laser-induced perturbation (DLIP) for bioimaging and chemical sensing
DE102008062650B9 (de) * 2008-12-17 2021-10-28 Carl Zeiss Meditec Ag Operationsmikroskop zur Beobachtung einer Infrarot-Fluoreszenz und Verfahren hierzu
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
DE102009040093A1 (de) * 2009-09-04 2011-04-07 Olympus Winter & Ibe Gmbh Medizinische Leuchte für Hintergrundlicht und Anregungslicht
JP5320233B2 (ja) * 2009-09-18 2013-10-23 富士フイルム株式会社 蛍光画像撮像装置
CN102333474A (zh) * 2009-10-20 2012-01-25 奥林巴斯医疗株式会社 荧光观察装置
US9743836B2 (en) * 2009-12-21 2017-08-29 Terumo Kabushiki Kaisha Excitation, detection, and projection system for visualizing target cancer tissue
US8974651B2 (en) 2010-04-17 2015-03-10 C.C. Imex Illuminator for visualization of fluorophores
US20120190990A1 (en) * 2010-06-25 2012-07-26 Konica Minolta Opto, Inc. Probe, Diagnosis Device, and Method for Using the Diagnosis Device
CN107582016B (zh) 2011-03-08 2020-04-28 诺瓦达克技术公司 全光谱led照明器
WO2012144055A1 (ja) * 2011-04-21 2012-10-26 パナソニック株式会社 光照射装置及び光照射方法
EP2757933B1 (de) 2011-09-22 2019-02-06 The George Washington University Systeme zur visualisierung von ablatiertem gewebe
WO2013044182A1 (en) 2011-09-22 2013-03-28 The George Washington University Systems and methods for visualizing ablated tissue
JP6398093B2 (ja) * 2012-04-13 2018-10-03 ベイカー ハート アンド ダイアベーツ インスティテュート アテローム斑の検出
WO2013190391A2 (en) 2012-06-21 2013-12-27 Novadaq Technologies Inc. Quantification and analysis of angiography and perfusion
US9952157B2 (en) 2012-07-17 2018-04-24 The Arizona Board Of Regents On Behalf Of The University Of Arizona Tissue imaging and visualization of lesions using reflectance and autofluorescence measurements
KR101385978B1 (ko) * 2012-08-09 2014-04-16 한국전기연구원 광학 진단 및 광 치료를 위한 복합 광원 장치
JP2014128394A (ja) 2012-12-28 2014-07-10 Hoya Corp 内視鏡装置
US10987011B2 (en) * 2013-01-28 2021-04-27 Oslo Universitetssykehus Hf Assessing circulatory failure
JP5480432B2 (ja) * 2013-07-17 2014-04-23 富士フイルム株式会社 蛍光画像撮像装置
KR101463005B1 (ko) * 2013-10-15 2014-11-18 (주)한국해양기상기술 특정 파장에 대한 형광 특성을 갖는 미생물 검사방법
DE102013111368A1 (de) * 2013-10-15 2015-04-16 Karl Storz Gmbh & Co. Kg Endoskopische, exoskopische oder mikroskopische Vorrichtung zur Fluoreszenzdiagnose
WO2015073871A2 (en) 2013-11-14 2015-05-21 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US20150141847A1 (en) 2013-11-20 2015-05-21 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
US10602917B2 (en) 2013-12-31 2020-03-31 Karl Storz Imaging, Inc. Switching between white light imaging and excitation light imaging leaving last video frame displayed
US10602918B2 (en) 2013-12-31 2020-03-31 Karl Storz Imaging, Inc. Switching between white light imaging and excitation light imaging leaving last video frame displayed
US9835587B2 (en) 2014-04-01 2017-12-05 C.C. Imex Electrophoresis running tank assembly
PL3171765T3 (pl) 2014-07-24 2022-01-03 University Health Network Zbieranie i analiza danych do celów diagnostycznych
EP3201607B1 (de) 2014-09-29 2020-12-30 Novadaq Technologies ULC Bildgebung eines zielfluorophors in einem biologischen material in anwesenheit von autofluoreszenz
CA2963450A1 (en) 2014-10-09 2016-04-14 Novadaq Technologies Inc. Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
EP3215001A4 (de) 2014-11-03 2018-04-04 Luxcath, LLC Systeme und verfahren zur beurteilung der kontaktqualität
CN113143440B (zh) 2014-11-03 2024-07-30 乔治华盛顿大学 用于损伤评估的系统和方法
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
DE102015011441A1 (de) * 2015-09-01 2017-03-02 Carl Zeiss Meditec Ag Fluoreszenzlichtdetektionssystem und Mikroskopiesystem
JP6743137B2 (ja) 2015-11-13 2020-08-19 ノバダック テクノロジーズ ユーエルシー ターゲットの照明およびイメージングのためのシステムおよび方法
EP3408654B1 (de) 2016-01-26 2022-08-03 Stryker European Operations Limited Flurorezenzbildgebungssystem und methode zur fluoreszenzbildgebung
US10293122B2 (en) 2016-03-17 2019-05-21 Novadaq Technologies ULC Endoluminal introducer with contamination avoidance
USD916294S1 (en) 2016-04-28 2021-04-13 Stryker European Operations Limited Illumination and imaging device
EP3469420A4 (de) 2016-06-14 2020-02-12 Novadaq Technologies ULC Verfahren und systeme zur adaptiven bildgebung zur verstärkung eines schwachen lichtsignals bei einer medizinischen visualisierung
US10537225B2 (en) * 2016-11-28 2020-01-21 Olympus Corporation Marking method and resecting method
JP6931705B2 (ja) 2017-02-10 2021-09-08 ノバダック テクノロジーズ ユーエルシー オープンフィールドハンドヘルド蛍光イメージングシステムおよび方法
DE102017222530A1 (de) * 2017-12-12 2019-06-13 Henkel Ag & Co. Kgaa Anordnung zum Ermitteln von Stoffwechselendprodukten in der Haut
JP7123166B2 (ja) * 2018-12-10 2022-08-22 オリンパス株式会社 画像記録装置、画像記録装置の作動方法及び内視鏡システム
DE102019101773B9 (de) * 2019-01-24 2021-11-25 Carl Zeiss Meditec Ag Mikroskopiesystem und Verfahren zum Betreiben eines Mikroskopiesystems
US11166623B2 (en) * 2019-04-23 2021-11-09 Arthrex, Inc. Field stop fluorescent indicator system and method
DE102019115276A1 (de) * 2019-06-06 2020-12-10 Karl Storz Se & Co. Kg Lichtquelle und System für die und Verfahren zur Fluoreszenzdiagnose
US20210052161A1 (en) * 2019-08-23 2021-02-25 Rebound Therapeutics Corporation Fluorescence imaging system
WO2021142368A1 (en) 2020-01-08 2021-07-15 460Medical, Inc. Systems and methods for optical interrogation of ablation lesions
WO2021243061A1 (en) 2020-05-27 2021-12-02 The George Washington University Lesion visualization using dual wavelength approach
WO2022027094A1 (en) 2020-08-04 2022-02-10 Baker Heart and Diabetes Institute Guidewire sensing apparatus
DE102021121025B4 (de) * 2021-08-12 2026-02-12 Karl Storz Se & Co. Kg Medizinische Bildgebungsvorrichtung, insbesondere Endoskop oder Exoskop
US20230139704A1 (en) * 2021-11-04 2023-05-04 Lumicell, Inc. Optical fiber fixtures for imaging devices
DE102024125695A1 (de) * 2024-09-06 2026-03-12 Karl Storz Se & Co. Kg Beleuchtungsvorrichtung, insbesondere für ein medizinisches Bildgebungsgerät wie ein Endoskop, Exoskop und/oder Mikroskop

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5940830A (ja) * 1982-08-31 1984-03-06 浜松ホトニクス株式会社 レ−ザ光パルスを用いた癌の診断装置
US4541438A (en) * 1983-06-02 1985-09-17 The Johns Hopkins University Localization of cancerous tissue by monitoring infrared fluorescence emitted by intravenously injected porphyrin tumor-specific markers excited by long wavelength light
JPS60256443A (ja) * 1984-05-31 1985-12-18 オムロン株式会社 画像計測装置
SE455646B (sv) * 1984-10-22 1988-07-25 Radians Innova Ab Fluorescensanordning
US4718417A (en) * 1985-03-22 1988-01-12 Massachusetts Institute Of Technology Visible fluorescence spectral diagnostic for laser angiosurgery
CN85100424B (zh) * 1985-04-01 1986-10-29 上海医疗器械研究所 恶性肿瘤固有荧光诊断仪
AT387860B (de) * 1985-09-16 1989-03-28 Optical Sensing Technology Verfahren und vorrichtung zur tumordiagnose mittels sera
US4930516B1 (en) * 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US5042494A (en) * 1985-11-13 1991-08-27 Alfano Robert R Method and apparatus for detecting cancerous tissue using luminescence excitation spectra
JPS62247232A (ja) * 1986-04-21 1987-10-28 Agency Of Ind Science & Technol 蛍光測定装置
GB2203831B (en) * 1986-07-07 1991-02-06 Academy Of Applied Sciences Apparatus and method for the diagnosis of malignant tumours
JPS63122421A (ja) * 1986-11-12 1988-05-26 株式会社東芝 内視鏡装置
US4852579A (en) * 1987-04-20 1989-08-01 Karl Storz Endoscopy Gmbh And Company Photocharacterization and treatment of normal abnormal and ectopic endometrium
JPH06105190B2 (ja) * 1988-03-31 1994-12-21 工業技術院長 信号解析装置
US5078150A (en) * 1988-05-02 1992-01-07 Olympus Optical Co., Ltd. Spectral diagnosing apparatus with endoscope
US4938205A (en) * 1988-05-27 1990-07-03 The University Of Connecticut Endoscope with traced raster and elemental photodetectors
SE8900612D0 (sv) * 1989-02-22 1989-02-22 Jonas Johansson Vaevnadskarakterisering utnyttjande ett blodfritt fluorescenskriterium
WO1990012536A1 (en) * 1989-04-14 1990-11-01 Massachusetts Institute Of Technology Spectral diagnosis of diseased tissue
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5131398A (en) * 1990-01-22 1992-07-21 Mediscience Technology Corp. Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence
US5071417A (en) * 1990-06-15 1991-12-10 Rare Earth Medical Lasers, Inc. Laser fusion of biological materials

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DE69212382D1 (de) 1996-08-29
DE69212382T2 (de) 1997-03-06
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CA2042075C (en) 2001-01-23
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