ATE140956T1 - Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium - Google Patents

Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Info

Publication number
ATE140956T1
ATE140956T1 AT90905151T AT90905151T ATE140956T1 AT E140956 T1 ATE140956 T1 AT E140956T1 AT 90905151 T AT90905151 T AT 90905151T AT 90905151 T AT90905151 T AT 90905151T AT E140956 T1 ATE140956 T1 AT E140956T1
Authority
AT
Austria
Prior art keywords
culture
cell number
compartment
sub
cell mass
Prior art date
Application number
AT90905151T
Other languages
English (en)
Inventor
Van Taiariol
Robert V Oakley
Peter Ventura
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Application granted granted Critical
Publication of ATE140956T1 publication Critical patent/ATE140956T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT90905151T 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium ATE140956T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/321,765 US5017490A (en) 1989-03-10 1989-03-10 Method for in vitro reproduction and growth of cells in culture medium

Publications (1)

Publication Number Publication Date
ATE140956T1 true ATE140956T1 (de) 1996-08-15

Family

ID=23251935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90905151T ATE140956T1 (de) 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Country Status (9)

Country Link
US (1) US5017490A (de)
EP (1) EP0418354B1 (de)
JP (1) JP2981684B2 (de)
AT (1) ATE140956T1 (de)
CA (1) CA2011917C (de)
DE (1) DE69027962T2 (de)
DK (1) DK0418354T3 (de)
ES (1) ES2092506T3 (de)
WO (1) WO1990010690A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027126C1 (de) * 1990-08-28 1991-12-12 Eberhard Prof. Dr. 2000 Hamburg De Bock
FI923023A7 (fi) * 1990-10-31 1992-06-29 Baxter Int Lähellään tapahtuvan verisuonittumisen aikaansaava istutemateriaali
US5330915A (en) * 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
IL102189A (en) * 1992-06-12 1995-07-31 Univ Ben Gurion Device for growing microorganisms
DE4303936C1 (de) * 1993-02-10 1994-08-18 Gore W L & Ass Gmbh Vorrichtung zur Entfernung von gasförmigen Stoffen aus einem Gasstrom
WO1995004521A1 (en) 1993-08-10 1995-02-16 W.L. Gore & Associates, Inc. Cell encapsulating device
JPH0780041A (ja) * 1993-09-20 1995-03-28 Terumo Corp 細胞保存バッグシステム
US5935847A (en) 1994-10-28 1999-08-10 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US6297046B1 (en) 1994-10-28 2001-10-02 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6024220A (en) 1995-06-07 2000-02-15 Baxter International Inc. Encapsulated seam for multilayer materials
US6391404B1 (en) 1995-06-07 2002-05-21 Baxter International Inc. Coextruded multilayer film materials and containers made therefrom
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US5964261A (en) 1996-05-29 1999-10-12 Baxter International Inc. Implantation assembly
DE19707497A1 (de) * 1996-08-16 1998-02-19 Boehringer Mannheim Gmbh Reaktionsbeutelvorrichtung zur Durchführung von mehrstufigen Kultivierungs/Separations-Vorgängen und/oder Reaktionen
CA2316739C (en) 1997-12-24 2011-06-21 Duphar International Research B.V. Preparation of cells for production of biologicals
US6183460B1 (en) 1998-01-22 2001-02-06 Baxter International Inc. Multi-use solution container having flaps
US7326564B2 (en) 2001-02-20 2008-02-05 St. Jude Medical, Inc. Flow system for medical device evaluation and production
US7754478B2 (en) * 2003-12-18 2010-07-13 Kaneka Corporation Device for cell culture
JP4771433B2 (ja) * 2004-02-23 2011-09-14 クレシー,ウッド,フランソワ,マリ ド より適切な細胞変異体を選択可能な移動型容器を備えた連続培養装置
EP1739165A1 (de) * 2005-06-29 2007-01-03 Cellution Biotech B.V. Verfahren und Vorrichtung zur Kultivierung von Zellen unter Verwendung von Wellenbewegung
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US20080131960A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Self standing bioreactor construction
US20080131959A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Bioreactor construction
US20080176318A1 (en) 2006-12-07 2008-07-24 Wilson John R Highly efficient devices and methods for culturing cells
TW200835790A (en) * 2007-01-22 2008-09-01 Malcolm Ian Wright A variable volume bioreactor
JP5023795B2 (ja) 2007-04-27 2012-09-12 東洋製罐株式会社 細胞培養方法、細胞培養システム、及び培地調整装置
US9441193B2 (en) * 2007-04-27 2016-09-13 Toyo Seikan Group Holdings, Ltd. Cell culture apparatus, cell culture system and cell culture method
US8114664B2 (en) * 2007-07-12 2012-02-14 Worcester Polytechnic Institute Scalable wall bioreactor for culture of plant and animal tissues
US8367400B2 (en) * 2008-03-21 2013-02-05 Corning Incorporated Culture vessel allowing large in situ scale up
WO2009123173A1 (ja) * 2008-04-01 2009-10-08 東洋製罐株式会社 培養容器、培養方法、及び培養装置
JP5309657B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養容器
JP5309658B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養方法、及び培養装置
US20100055764A1 (en) * 2008-08-27 2010-03-04 Martin Gregory R Cell culture apparatus and method
JP2012517829A (ja) * 2009-02-18 2012-08-09 バイオレックス・セラピューティクス インコーポレイテッド 生体材料を処理するための無菌バイオリアクタ・システム
EP2424982A4 (de) * 2009-04-29 2013-01-09 Crecy Eudes De Adaption von mikroorganismen für landwirtschaftsprodukte
JP5740841B2 (ja) * 2010-05-19 2015-07-01 東洋製罐グループホールディングス株式会社 細胞培養方法、細胞培養装置、及び細胞培養装置の制御方法
DE102014202261A1 (de) * 2014-02-07 2015-08-27 Eurozyto Gmbh Behältnis und Set zur Bereitstellung parenteraler Nahrung
JP6405690B2 (ja) * 2014-05-09 2018-10-17 東洋製罐グループホールディングス株式会社 複室培養容器、及び細胞培養方法
CN120905022A (zh) * 2014-05-28 2025-11-07 思拓凡瑞典有限公司 用于细胞培养的袋组件
US10731118B2 (en) 2014-05-28 2020-08-04 Ge Healthcare Bio-Sciences Corp. Bag assembly for cultivation of cells
EP3252140B1 (de) 2015-01-30 2022-03-02 Toyo Seikan Group Holdings, Ltd. Zellkulturverfahren und zellkulturvorrichtung
WO2016124505A1 (en) * 2015-02-05 2016-08-11 General Electric Company Bioreactor system for cell cultivation
JP6706612B2 (ja) * 2015-03-20 2020-06-10 積水化学工業株式会社 微生物の培養方法及び培養装置
JP7026990B2 (ja) * 2016-07-05 2022-03-01 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 調節容積式の細胞培養のための装置および方法
CN111801412A (zh) * 2018-03-02 2020-10-20 赛默电子Led有限公司 用于分离生物悬浮液的一次性离心容器和使用方法
EP3650528A1 (de) * 2018-11-08 2020-05-13 Aglaris Ltd Zellkultursystem und -verfahren
EP4352197A1 (de) * 2021-06-07 2024-04-17 SOTIO Biotech Inc. Zellkulturgefäss zur verwendung bei der herstellung von zellprodukten
GB2617629B (en) * 2022-06-29 2024-04-10 Hoxton Farms Ltd System for cell culture

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1792450A (en) * 1927-10-24 1931-02-10 Stich Eugen Process and appliance for fermenting sacchariferous liquids
US3102082A (en) * 1961-07-17 1963-08-27 John H Brewer Apparatus and method for culturing micro-organisms
US3257072A (en) * 1963-01-07 1966-06-21 Cryogenic Eng Co Whole blood storage structure
US3814395A (en) * 1964-02-27 1974-06-04 Kaelin J R Aeration plant for clarifying sewage and waste effluents
US3911918A (en) * 1972-04-13 1975-10-14 Ralph D Turner Blood collection, storage and administering bag
US3946780A (en) * 1973-01-04 1976-03-30 Sellers John C Fermentation container
US4132594A (en) * 1976-06-28 1979-01-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Gas diffusion liquid storage bag and method of use for storing blood
US4059486A (en) * 1976-11-03 1977-11-22 Monsanto Company Cell culture process
IT1122151B (it) * 1978-07-26 1986-04-23 Biotest Serum Institut Gmbh Sistema di sacchetti per la coltura di sangue
CS231615B1 (en) * 1981-12-29 1984-12-14 Vladislav Vlcek Method of cultivation of cells of higher organism and device to perform the method
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4632244A (en) * 1986-02-19 1986-12-30 Boris Landau Multiple chamber flexible container
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
US4734373A (en) * 1986-06-24 1988-03-29 Bartal Arie H Apparatus for enhancing cell growth, preservation and transport
US4717668A (en) * 1986-12-12 1988-01-05 Baxter Travenol Laboratories, Inc. Plastic roller bottle for suspension cultures

Also Published As

Publication number Publication date
JP2981684B2 (ja) 1999-11-22
JPH03505164A (ja) 1991-11-14
DK0418354T3 (da) 1996-08-26
US5017490A (en) 1991-05-21
DE69027962D1 (de) 1996-09-05
EP0418354A1 (de) 1991-03-27
EP0418354B1 (de) 1996-07-31
CA2011917A1 (en) 1990-09-10
ES2092506T3 (es) 1996-12-01
WO1990010690A1 (en) 1990-09-20
DE69027962T2 (de) 1997-01-02
EP0418354A4 (en) 1991-12-27
CA2011917C (en) 2000-01-25

Similar Documents

Publication Publication Date Title
ATE140956T1 (de) Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium
DE69637656D1 (de) Methoden zur Züchtung von Tierzellen
CA2209211A1 (en) Production of a contractile smooth muscle
AU525008B2 (en) Method and apparatus for growing biological nutrient froma source of nutrient
ATE419332T1 (de) Verfahren zur zellkultivierung in einer monoschicht
ES8609459A1 (es) Procedimiento para la preparacion de pelicula de celulosa
ES2150938T3 (es) Produccion mejorada de taxol y taxanos mediante cultivos celulares de especies de taxus.
ATE37764T1 (de) Verfahren zur vermehrung von pflanzlichen gewebekulturen.
ATE138684T1 (de) Verfahren zur erzeugung von zellmasse und/oder fermentierungsprodukten unter sterilen bedingungen sowie vorrichtung zur durchführung des verfahrens
ATE46358T1 (de) Verfahren zur zuechtung von lyophilisierten mikroorganismen.
ATE67787T1 (de) Verfahren zur herstellung von proteinen mittels induzierbarer expressionssysteme in in-vivovermehrten, genetisch modifizierten eukaryotischen wirtszellen.
EP0380692A4 (en) Plant tissue culture process
RU96106889A (ru) Способ получения селенсодержащего препарата биомассы спирулины
EP0340783A3 (en) Apparatus for culturing animal cells, method of culturing thereof and diagnostics of the culture
DE3677217D1 (de) Verfahren zum regenerieren von mais.
CH611774A5 (en) Process for the culture of cells of higher plants on lactose-containing media
GB2003926A (en) Microbiological process
ATE76251T1 (de) Verfahren zur kultur von pflanzengewebe.
FR2614498B1 (fr) Procede de culture de champignons, sur compost supplemente par un apport proteique et un apport enzymatique
ATE12646T1 (de) Antibiotikum am-5344-a2 und verfahren zu dessen herstellung.
DE69004714D1 (de) Verfahren zur Zucht von Pilzen und Substrat zur Durchführung dieses Verfahrens.
EP0299067A4 (de) Zuchtmedium für pflanzen.
UA10728A (uk) Спосіб розмhожеhhя hапівкарликових підщепів яблуhі в культурі ткаhиhи
ATE115183T1 (de) Zellzüchtungsverfahren.
KR940000572A (ko) 사람 인터루킨- 6 단백질을 생산하는 식물 및 그의 제조방법

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee