ATE140976T1 - Genexpression in hefezellen - Google Patents

Genexpression in hefezellen

Info

Publication number
ATE140976T1
ATE140976T1 AT91300903T AT91300903T ATE140976T1 AT E140976 T1 ATE140976 T1 AT E140976T1 AT 91300903 T AT91300903 T AT 91300903T AT 91300903 T AT91300903 T AT 91300903T AT E140976 T1 ATE140976 T1 AT E140976T1
Authority
AT
Austria
Prior art keywords
tat
hiv
control sequence
protein
regulatory control
Prior art date
Application number
AT91300903T
Other languages
English (en)
Inventor
Colin William Dykes
Joachim Franz Ernst
Adrian Norman Hobden
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE140976T1 publication Critical patent/ATE140976T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/94Saccharomyces
    • Y10S435/942Saccharomyces cerevisiae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91300903T 1990-02-09 1991-02-04 Genexpression in hefezellen ATE140976T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909003010A GB9003010D0 (en) 1990-02-09 1990-02-09 Gene expression in yeast cells

Publications (1)

Publication Number Publication Date
ATE140976T1 true ATE140976T1 (de) 1996-08-15

Family

ID=10670759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91300903T ATE140976T1 (de) 1990-02-09 1991-02-04 Genexpression in hefezellen

Country Status (5)

Country Link
US (1) US5238822A (de)
EP (1) EP0441582B1 (de)
AT (1) ATE140976T1 (de)
DE (1) DE69121118D1 (de)
GB (1) GB9003010D0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733720A (en) * 1992-06-18 1998-03-31 Washington University Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor
US5958676A (en) * 1992-06-18 1999-09-28 Washington University Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor
US5891994A (en) * 1997-07-11 1999-04-06 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
GB9720585D0 (en) * 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
US6399067B1 (en) 2000-04-28 2002-06-04 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
CA2597373A1 (en) 2005-02-15 2006-08-24 Thymon, L.L.C. Methods and compositions for impairing multiplication of hiv-1
WO2007109564A2 (en) * 2006-03-17 2007-09-27 University Of Massachusetts Yeast cell particles as oral delivery vehicles for antigens
GB0802224D0 (en) * 2008-02-06 2008-03-12 Inst Superiore Di Sanito Process for the production of vaccine components

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405712A (en) * 1981-07-01 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services LTR-Vectors
US4738922A (en) * 1984-05-25 1988-04-19 Dana Farber Cancer Institute Trans-acting transcriptional factors
PT83682B (en) * 1985-11-06 1988-12-05 Smithkline Beckman Corp Process for the expression of an aids virus gene
EP0349598A1 (de) * 1987-03-13 1990-01-10 Schering Corporation Verfahren zur stimulierung der gen-expression
EP0291893A1 (de) * 1987-05-19 1988-11-23 The Du Pont Merck Pharmaceutical Company Stabile menschliche Zellinien, die ein Indikatorgenprodukt unter virusspezifischen genetischen Kontrollen exprimieren
AU3006789A (en) * 1988-02-24 1989-08-24 Smithkline Beckman Corporation Expression of hiv binding proteins
EP0352060A3 (de) * 1988-07-21 1990-12-27 Takeda Chemical Industries, Ltd. Expressionsplasmid und dessen Verwendung
US5278042A (en) * 1989-02-06 1994-01-11 The United States Of America As Represented By The Department Of Health & Human Services Method for detecting inhibitors of tat protein

Also Published As

Publication number Publication date
GB9003010D0 (en) 1990-04-04
DE69121118D1 (de) 1996-09-05
US5238822A (en) 1993-08-24
EP0441582B1 (de) 1996-07-31
EP0441582A1 (de) 1991-08-14

Similar Documents

Publication Publication Date Title
AU543168B2 (en) Stabilizing and selecting recombinant dna host cells
ATE76428T1 (de) Expression und sekretion von polypeptiden in eukaryoten unter kontrolle eines adenoviruspromotors.
WO1994003616A3 (fr) Vecteur de clonage et/ou de sequençage
NO173741C (no) DNA-sekvens for modifisert protein C, vektor inneholdende denne, patte-dyrceller transfektert med vektorer, og fremgangsmaate for fremstilling av nevnte protein
ATE520783T1 (de) Lentivirale vektoren
DK547185D0 (da) Vektorer til ekspression af hirudin, transformerede celler og fremgangsmaade til fremstilling af hirudin
ATE391175T1 (de) Multidrug resistenz gen
DE3588096D1 (de) Hefevektor
FI863430A0 (fi) Repressoituvat hiivapromoottorit
DE69121118D1 (de) Genexpression in Hefezellen
DE3678109D1 (de) Flexible bis weiche formkoerper auf der basis von vinylchlorid-acrylsaeureester-pfropfcopolymerisat.
KR920702417A (ko) Tcf-ii의 아미노산 배열을 코드하는 dna를 함유한 플라스미드, 형질전환세포, 및 이것을 사용하여 생리 활성물질을 생산하는 방법
EP0037723A3 (de) Expression von genomischen Klonen von Hormonen
ATE142264T1 (de) Rekombinante herstellung von a-ketten- polypeptiden von pdgf
DK0724639T3 (da) Fremgangsmåder til udvælgelse af rekombinante værtsceller, der udtrykker høje niveauer af et ønsket protein
DE3688671D1 (de) Menschliches interferon-beta2a vektoren, die gene enthalten, die fuer das genannte interferon kodieren zellinien, die dieses produzieren und verwendung des genannten interferons als pharmazeutikum.
EP0320806A3 (de) An T-Zellenaktivierung gebundenes Gen
ES2123569T3 (es) Regulacion de genes en celulas de mamifero dependiente de ecdiesteroides.
DE3577994D1 (de) Vergroessernde virale dna-segmente.
DE69231689D1 (de) Zusammensetzung von antwortelementen und ihre verwendung als proben
ATE50597T1 (de) Alpha-interferon gx-1.
ES2053818T3 (es) Vectores de expresion para la sintesis de proteinas y replicones de plasmidos y cassettes de secuencias para utilizarse en la construccion de tales vectores.
ATE189479T1 (de) Expressionsvektoren zur synthese von proteinen in der spalthefe schizosaccharomyces pombe
ATE109831T1 (de) Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus.
DK391185A (da) Rekombinant saccharomyces

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties