ATE140976T1 - Genexpression in hefezellen - Google Patents

Genexpression in hefezellen

Info

Publication number
ATE140976T1
ATE140976T1 AT91300903T AT91300903T ATE140976T1 AT E140976 T1 ATE140976 T1 AT E140976T1 AT 91300903 T AT91300903 T AT 91300903T AT 91300903 T AT91300903 T AT 91300903T AT E140976 T1 ATE140976 T1 AT E140976T1
Authority
AT
Austria
Prior art keywords
tat
hiv
control sequence
protein
regulatory control
Prior art date
Application number
AT91300903T
Other languages
English (en)
Inventor
Colin William Dykes
Joachim Franz Ernst
Adrian Norman Hobden
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE140976T1 publication Critical patent/ATE140976T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91300903T 1990-02-09 1991-02-04 Genexpression in hefezellen ATE140976T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909003010A GB9003010D0 (en) 1990-02-09 1990-02-09 Gene expression in yeast cells

Publications (1)

Publication Number Publication Date
ATE140976T1 true ATE140976T1 (de) 1996-08-15

Family

ID=10670759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91300903T ATE140976T1 (de) 1990-02-09 1991-02-04 Genexpression in hefezellen

Country Status (5)

Country Link
US (1) US5238822A (de)
EP (1) EP0441582B1 (de)
AT (1) ATE140976T1 (de)
DE (1) DE69121118D1 (de)
GB (1) GB9003010D0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733720A (en) * 1992-06-18 1998-03-31 Washington University Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor
US5958676A (en) * 1992-06-18 1999-09-28 Washington University Genetically engineered cell lines for detecting infectious herpesvirus and methods therefor
US5891994A (en) * 1997-07-11 1999-04-06 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
GB9720585D0 (en) * 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
US6399067B1 (en) * 2000-04-28 2002-06-04 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
JP2008535783A (ja) 2005-02-15 2008-09-04 サイモン・エル・エル・シー Ｈｉｖ−１の増殖を弱めるための方法および組成物
US20080044438A1 (en) * 2006-03-17 2008-02-21 Ostroff Gary R Yeast Cell Particles As Oral Delivery Vehicles For Antigens
GB0802224D0 (en) * 2008-02-06 2008-03-12 Inst Superiore Di Sanito Process for the production of vaccine components

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405712A (en) * 1981-07-01 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services LTR-Vectors
US4738922A (en) * 1984-05-25 1988-04-19 Dana Farber Cancer Institute Trans-acting transcriptional factors
PT83682B (en) * 1985-11-06 1988-12-05 Smithkline Beckman Corp Process for the expression of an aids virus gene
WO1988007083A1 (en) * 1987-03-13 1988-09-22 Schering Corporation Method for stimulating gene expression
EP0291893A1 (de) * 1987-05-19 1988-11-23 The Du Pont Merck Pharmaceutical Company Stabile menschliche Zellinien, die ein Indikatorgenprodukt unter virusspezifischen genetischen Kontrollen exprimieren
AU3006789A (en) * 1988-02-24 1989-08-24 Smithkline Beckman Corporation Expression of hiv binding proteins
JPH02150283A (ja) * 1988-07-21 1990-06-08 Takeda Chem Ind Ltd 発現プラスミドおよびその用途
US5278042A (en) * 1989-02-06 1994-01-11 The United States Of America As Represented By The Department Of Health & Human Services Method for detecting inhibitors of tat protein

Also Published As

Publication number Publication date
DE69121118D1 (de) 1996-09-05
GB9003010D0 (en) 1990-04-04
EP0441582A1 (de) 1991-08-14
EP0441582B1 (de) 1996-07-31
US5238822A (en) 1993-08-24

Similar Documents

Publication Publication Date Title
AU543168B2 (en) Stabilizing and selecting recombinant dna host cells
ATE76428T1 (de) Expression und sekretion von polypeptiden in eukaryoten unter kontrolle eines adenoviruspromotors.
WO1994003616A3 (fr) Vecteur de clonage et/ou de sequençage
NO173741C (no) DNA-sekvens for modifisert protein C, vektor inneholdende denne, patte-dyrceller transfektert med vektorer, og fremgangsmaate for fremstilling av nevnte protein
ATE520783T1 (de) Lentivirale vektoren
DK547185D0 (da) Vektorer til ekspression af hirudin, transformerede celler og fremgangsmaade til fremstilling af hirudin
ATE391175T1 (de) Multidrug resistenz gen
DK224185D0 (da) Vektor til inkorporering i gaercellers chromosomer
ATE140976T1 (de) Genexpression in hefezellen
KR920702417A (ko) Tcf-ii의 아미노산 배열을 코드하는 dna를 함유한 플라스미드, 형질전환세포, 및 이것을 사용하여 생리 활성물질을 생산하는 방법
EP0037723A3 (de) Expression von genomischen Klonen von Hormonen
DE3855504D1 (de) Rekombinante Herstellung von A-Ketten-Polypeptiden von PDGF
PT599971E (pt) Promotor de levedura e sua utilizacao
EP0320806A3 (de) An T-Zellenaktivierung gebundenes Gen
ES2123569T3 (es) Regulacion de genes en celulas de mamifero dependiente de ecdiesteroides.
DE69231689D1 (de) Zusammensetzung von antwortelementen und ihre verwendung als proben
EP0154566A3 (en) Viral enhancer dna segments
ES2053818T3 (es) Vectores de expresion para la sintesis de proteinas y replicones de plasmidos y cassettes de secuencias para utilizarse en la construccion de tales vectores.
ATE189479T1 (de) Expressionsvektoren zur synthese von proteinen in der spalthefe schizosaccharomyces pombe
ATE109831T1 (de) Defektives rekombinantes retrovirus, seine verwendung zur integration von proteine codierenden sequenzen im genom von gewebekulturen, infizierbar mit dem entsprechenden wildretrovirus, und dns zur herstellung dieses rekombinanten retrovirus.
DK391185D0 (da) Rekombinant saccharomyces
ATE159296T1 (de) Promotor-regulator und das für indikator-protein kodierende gen enthaltendes chimäres gen
IL83435A (en) Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector
DE69119461D1 (de) Strukturgen von membrangebundenem Alkoholdehydrogenase-Komplex, Plasmid, das dieses Gen enthält und transformierte Essigsäurebakterien

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties