ATE141159T1 - Pharmazeutische zusammensetzung mit kontrollierter freigabe und bioadhäsiven eigenschaften - Google Patents

Pharmazeutische zusammensetzung mit kontrollierter freigabe und bioadhäsiven eigenschaften

Info

Publication number
ATE141159T1
ATE141159T1 AT92109080T AT92109080T ATE141159T1 AT E141159 T1 ATE141159 T1 AT E141159T1 AT 92109080 T AT92109080 T AT 92109080T AT 92109080 T AT92109080 T AT 92109080T AT E141159 T1 ATE141159 T1 AT E141159T1
Authority
AT
Austria
Prior art keywords
composition
pharmaceutical composition
controlled release
release
bioadhesive properties
Prior art date
Application number
AT92109080T
Other languages
English (en)
Inventor
Giancarlo Santus
Giuseppe Bottoni
Giovanni Sala
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of ATE141159T1 publication Critical patent/ATE141159T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92109080T 1991-05-30 1992-05-29 Pharmazeutische zusammensetzung mit kontrollierter freigabe und bioadhäsiven eigenschaften ATE141159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911486A IT1250421B (it) 1991-05-30 1991-05-30 Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.

Publications (1)

Publication Number Publication Date
ATE141159T1 true ATE141159T1 (de) 1996-08-15

Family

ID=11360019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92109080T ATE141159T1 (de) 1991-05-30 1992-05-29 Pharmazeutische zusammensetzung mit kontrollierter freigabe und bioadhäsiven eigenschaften

Country Status (9)

Country Link
US (1) US5472704A (de)
EP (1) EP0516141B1 (de)
JP (1) JPH07215843A (de)
AT (1) ATE141159T1 (de)
DE (1) DE69212710T2 (de)
DK (1) DK0516141T3 (de)
ES (1) ES2091363T3 (de)
GR (1) GR3020813T3 (de)
IT (1) IT1250421B (de)

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US5472704A (en) 1995-12-05
DE69212710T2 (de) 1996-12-19
ITMI911486A0 (it) 1991-05-30
IT1250421B (it) 1995-04-07
ITMI911486A1 (it) 1992-11-30
EP0516141B1 (de) 1996-08-14
DE69212710D1 (de) 1996-09-19
DK0516141T3 (da) 1996-09-02
ES2091363T3 (es) 1996-11-01
GR3020813T3 (en) 1996-11-30
EP0516141A1 (de) 1992-12-02
JPH07215843A (ja) 1995-08-15

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