ATE141331T1 - Vektor zur expression von membranrezeptoren aus säugetieren in einzelligen organismen und methode zur untersuchung von liganden, die diese rezeptoren erkennen - Google Patents
Vektor zur expression von membranrezeptoren aus säugetieren in einzelligen organismen und methode zur untersuchung von liganden, die diese rezeptoren erkennenInfo
- Publication number
- ATE141331T1 ATE141331T1 AT89400768T AT89400768T ATE141331T1 AT E141331 T1 ATE141331 T1 AT E141331T1 AT 89400768 T AT89400768 T AT 89400768T AT 89400768 T AT89400768 T AT 89400768T AT E141331 T1 ATE141331 T1 AT E141331T1
- Authority
- AT
- Austria
- Prior art keywords
- receptors
- studying
- vector
- receptor
- ligands
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 4
- 102000005962 receptors Human genes 0.000 title abstract 4
- 108020003175 receptors Proteins 0.000 title abstract 4
- 239000013598 vector Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 102000006240 membrane receptors Human genes 0.000 title abstract 2
- 108020004084 membrane receptors Proteins 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 1
- XKMLYUALXHKNFT-UUOKFMHZSA-N Guanosine-5'-triphosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O XKMLYUALXHKNFT-UUOKFMHZSA-N 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101001059240 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Site-specific recombinase Flp Proteins 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Photometry And Measurement Of Optical Pulse Characteristics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8803475A FR2628750B1 (fr) | 1988-03-21 | 1988-03-21 | Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire |
| CA000599327A CA1341448C (fr) | 1988-03-21 | 1989-05-10 | Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire liant une proteine g |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE141331T1 true ATE141331T1 (de) | 1996-08-15 |
Family
ID=32962979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89400768T ATE141331T1 (de) | 1988-03-21 | 1989-03-17 | Vektor zur expression von membranrezeptoren aus säugetieren in einzelligen organismen und methode zur untersuchung von liganden, die diese rezeptoren erkennen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5242822A (de) |
| EP (1) | EP0344024B1 (de) |
| JP (1) | JPH029375A (de) |
| AT (1) | ATE141331T1 (de) |
| CA (1) | CA1341448C (de) |
| DE (1) | DE68926931T2 (de) |
| FR (1) | FR2628750B1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1252444B (it) * | 1990-09-07 | 1995-06-16 | Enichem Spa | Metodo per l'identificazione e/o l'isolamento di geni che codificano per recettori di membrana. |
| DK0548165T3 (da) * | 1990-09-13 | 2001-07-16 | Univ Duke | Ekspression af G-proteinkoblede receptorer i gær |
| FR2666898A1 (fr) * | 1990-09-18 | 1992-03-20 | Toledano Jacques | Dispositif et procede de dosage rapide de recepteurs membranaires ou de leurs ligands. |
| JP2987818B2 (ja) * | 1990-12-14 | 1999-12-06 | 塩野義製薬株式会社 | Txa2受容体およびそれをコードする遺伝子 |
| EP0668930B1 (de) * | 1991-10-01 | 2002-12-18 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Ein verfahren zur identifikation von liganden und ligandantagonisten |
| DE69229283T2 (de) * | 1991-11-06 | 1999-09-23 | Garvan Institute Of Medical Research, Darlinghurst | Humaner neuropeptid y-y1 rezeptor |
| AU672768B2 (en) * | 1991-12-02 | 1996-10-17 | Lundbeck Research Usa, Inc. | DNA encoding a human 5-HT-1E receptor and uses thereof |
| US6225080B1 (en) * | 1992-03-23 | 2001-05-01 | George R. Uhl | Mu-subtype opioid receptor |
| US5472866A (en) * | 1992-12-24 | 1995-12-05 | Synaptic Pharmaceutical Corporation | DNA encoding 5-HT4A serotonin receptors |
| US6864060B1 (en) | 1993-03-31 | 2005-03-08 | Cadus Technologies, Inc. | Yeast cells expressing modified G proteins and methods of use therefor |
| WO1995009237A2 (en) * | 1993-09-28 | 1995-04-06 | Allelix Biopharmaceuticals Inc. | Expression of human d4 dopamine receptors in stable cell lines |
| WO1995016772A1 (en) | 1993-12-14 | 1995-06-22 | Cornell Research Foundation, Inc. | Adenovirus gene expression system |
| WO1995019986A1 (en) * | 1994-01-21 | 1995-07-27 | American Cyanamid Company | cDNAs ENCODING PROTEINS CLOSELY RELATED TO OPIOID RECEPTORS |
| US5731425A (en) * | 1994-10-28 | 1998-03-24 | Eastman Kodak Company | Polypeptide surface marker for cells |
| EP0866856A1 (de) * | 1995-11-14 | 1998-09-30 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Crf analoge und deren verwendung in photoaffinitätsmarkierung von crf-rezeptoren |
| WO1999064567A1 (de) * | 1998-06-05 | 1999-12-16 | Discovery Technologies Ltd. | Transformierte zell-linien, die heterologe g-protein-gekoppelte rezeptoren exprimieren |
| US7081360B2 (en) | 1998-07-28 | 2006-07-25 | Cadus Technologies, Inc. | Expression of G protein-coupled receptors with altered ligand binding and/or coupling properties |
| US6379903B1 (en) | 1999-10-08 | 2002-04-30 | Sigma-Aldrich Co. | Purification of recombinant proteins fused to multiple epitopes |
| CN119584971A (zh) * | 2022-04-11 | 2025-03-07 | 密歇根大学董事会 | 肽功能的化学遗传调控 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4615974A (en) * | 1981-08-25 | 1986-10-07 | Celltech Limited | Yeast expression vectors |
| US4859609A (en) * | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
| DK0548165T3 (da) * | 1990-09-13 | 2001-07-16 | Univ Duke | Ekspression af G-proteinkoblede receptorer i gær |
-
1988
- 1988-03-21 FR FR8803475A patent/FR2628750B1/fr not_active Expired - Lifetime
-
1989
- 1989-03-17 DE DE68926931T patent/DE68926931T2/de not_active Revoked
- 1989-03-17 JP JP1063981A patent/JPH029375A/ja active Pending
- 1989-03-17 EP EP89400768A patent/EP0344024B1/de not_active Revoked
- 1989-03-17 AT AT89400768T patent/ATE141331T1/de not_active IP Right Cessation
- 1989-05-10 CA CA000599327A patent/CA1341448C/fr not_active Expired - Fee Related
-
1991
- 1991-03-25 US US07/675,110 patent/US5242822A/en not_active Expired - Lifetime
-
1995
- 1995-04-13 US US08/422,612 patent/US6645755B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68926931D1 (de) | 1996-09-19 |
| CA1341448C (fr) | 2003-11-25 |
| FR2628750A1 (fr) | 1989-09-22 |
| US6645755B1 (en) | 2003-11-11 |
| FR2628750B1 (fr) | 1991-11-08 |
| EP0344024A1 (de) | 1989-11-29 |
| EP0344024B1 (de) | 1996-08-14 |
| JPH029375A (ja) | 1990-01-12 |
| US5242822A (en) | 1993-09-07 |
| DE68926931T2 (de) | 1997-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| RZN | Patent revoked |