ATE432346T1 - Polypeptid-destabiliserendes protein in zellen unter aeroben bedingungen und dieses codierende dna - Google Patents

Polypeptid-destabiliserendes protein in zellen unter aeroben bedingungen und dieses codierende dna

Info

Publication number: ATE432346T1
Authority: AT; Austria
Prior art keywords: cells; dna; protein; polypeptide; cells under
Prior art date: 2001-06-05

Application number

AT02730898T

Other languages

English (en)

Inventor

Masahiro Hiraoka

Shinae Kondoh

Hiroshi Harada

Original Assignee

Masahiro Hiraoka

Shinae Kondoh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-05

Filing date

2002-06-04

Publication date

2009-06-15

2002-06-04 Application filed by Masahiro Hiraoka, Shinae Kondoh filed Critical Masahiro Hiraoka

2009-06-15 Application granted granted Critical

2009-06-15 Publication of ATE432346T1 publication Critical patent/ATE432346T1/de

Links

108090000623 proteins and genes Proteins 0.000 title abstract 4
102000004169 proteins and genes Human genes 0.000 title abstract 4
229920001184 polypeptide Polymers 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
230000000368 destabilizing effect Effects 0.000 title 1
102000037865 fusion proteins Human genes 0.000 abstract 4
108020001507 fusion proteins Proteins 0.000 abstract 4
206010021143 Hypoxia Diseases 0.000 abstract 3
230000001146 hypoxic effect Effects 0.000 abstract 3
239000013598 vector Substances 0.000 abstract 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
230000006641 stabilisation Effects 0.000 abstract 2
238000011105 stabilization Methods 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
108010077850 Nuclear Localization Signals Proteins 0.000 abstract 1
239000000824 cytostatic agent Substances 0.000 abstract 1
230000001085 cytostatic effect Effects 0.000 abstract 1
239000003145 cytotoxic factor Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000001415 gene therapy Methods 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
238000012544 monitoring process Methods 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1
230000009466 transformation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4733—Acute pancreatitis-associated protein

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT02730898T 2001-06-05 2002-06-04 Polypeptid-destabiliserendes protein in zellen unter aeroben bedingungen und dieses codierende dna ATE432346T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2001169949		2001-06-05
JP2001169948		2001-06-05
PCT/JP2002/005482 WO2002099104A1 (fr)	2001-06-05	2002-06-04	Polypeptide destabilisant une proteine dans des cellules dans des conditions aerobies et adn codant pour ce polypeptide

Publications (1)

Publication Number	Publication Date
ATE432346T1 true ATE432346T1 (de)	2009-06-15

Family

ID=26616379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02730898T ATE432346T1 (de)	2001-06-05	2002-06-04	Polypeptid-destabiliserendes protein in zellen unter aeroben bedingungen und dieses codierende dna

Country Status (8)

Country	Link
US (1)	US7700754B1 (de)
EP (1)	EP1403365B1 (de)
JP (1)	JP4130955B2 (de)
AT (1)	ATE432346T1 (de)
AU (1)	AU2002304163C1 (de)
CA (1)	CA2449802C (de)
DE (1)	DE60232443D1 (de)
WO (1)	WO2002099104A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003208684A1 (en) *	2002-03-05	2003-09-16	Angiogenetics Sweden Ab	Critical hypoxia-inducible factor-1alpha residues, products and methods related thereto
ES2649817T3 (es)	2002-04-05	2018-01-15	Roche Innovation Center Copenhagen A/S	Compuestos oligom¿¿ricos para la modulaci¿®n de la expresi¿®n de HIF-1¿Á
US9447138B2 (en)	2004-11-09	2016-09-20	Roche Innovation Center Copenhagen A/S	Potent LNA oligonucleotides for the inhibition of HIF-1a expression
BRPI0515726A8 (pt)	2004-11-09	2017-09-12	Santaris Pharma As	Oligonucleotídeos de lna potentes para a inibição de expressão de hif-1a
WO2006095846A1 (ja) *	2005-03-11	2006-09-14	Kansai Technology Licensing Organization Co., Ltd.	病態の状態をリアルタイムで観察可能なモデル動物とそれを可能にする遺伝子構築物及びその使用
US20110286972A1 (en) *	2008-01-16	2011-11-24	Katsuhito Takahashi	Virus growing in hypoxic cell or virus vector expressing gene therein
JP6022470B2 (ja)	2010-11-24	2016-11-09	タカラバイオユーエスエー，インコーポレイテッド	分散型タンパク質形質導入ドメインを含む誘導性発現系転写モジュレータおよびその使用方法
US20120190107A1 (en) *	2011-01-26	2012-07-26	Dwayne Bisgrove	Enhanced protein transduction
JP2018521689A (ja) *	2015-06-17	2018-08-09	ポセイダセラピューティクス，インコーポレイテッド	タンパク質をゲノム内の特定の遺伝子座に導くための組成物および方法
EP4215245A1 (de) *	2022-01-19	2023-07-26	Innovative Cellular Therapeutics Holdings, Ltd.	Verbesserte chimäre antigenrezeptorzellen in einer hypoxischen tumormikroumgebung
WO2026016166A1 (zh) *	2024-07-19	2026-01-22	上海鑫湾生物科技有限公司	一种响应缺氧环境的差异化基因表达调控系统及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5804604A (en) *	1989-12-21	1998-09-08	Biogen, Inc.	Tat-derived transport polypeptides and fusion proteins
EP0903408A3 (de) *	1992-08-21	2005-11-02	Biogen, Inc.	Tat-derivate Transport-Polypeptide
US5882914A (en) *	1995-06-06	1999-03-16	The Johns Hopkins University School Of Medicine	Nucleic acids encoding the hypoxia inducible factor-1
US20030040038A1 (en) *	1997-08-22	2003-02-27	Steven F. Dowdy	Inducible regulatory system and use thereof
GB9911047D0 (en)	1999-05-12	1999-07-14	Isis Innovation	Assay method and means
WO2001019393A1 (en)	1999-09-13	2001-03-22	Cornell Research Foundation, Inc.	Delivering to eucaryotic cells bacterial proteins that are secreted via type iii secretion systems

2002
- 2002-06-04 AT AT02730898T patent/ATE432346T1/de not_active IP Right Cessation
- 2002-06-04 US US10/479,700 patent/US7700754B1/en active Active
- 2002-06-04 CA CA2449802A patent/CA2449802C/en not_active Expired - Lifetime
- 2002-06-04 JP JP2003502213A patent/JP4130955B2/ja not_active Expired - Lifetime
- 2002-06-04 EP EP02730898A patent/EP1403365B1/de not_active Expired - Lifetime
- 2002-06-04 WO PCT/JP2002/005482 patent/WO2002099104A1/ja not_active Ceased
- 2002-06-04 AU AU2002304163A patent/AU2002304163C1/en not_active Expired
- 2002-06-04 DE DE60232443T patent/DE60232443D1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7700754B1 (en)	2010-04-20
EP1403365A1 (de)	2004-03-31
JPWO2002099104A1 (ja)	2004-09-16
EP1403365A4 (de)	2005-01-19
CA2449802A1 (en)	2002-12-12
AU2002304163B2 (en)	2007-05-17
WO2002099104A1 (fr)	2002-12-12
EP1403365B1 (de)	2009-05-27
AU2002304163C1 (en)	2009-01-08
JP4130955B2 (ja)	2008-08-13
CA2449802C (en)	2012-02-07
AU2002304163B8 (en)	2002-12-16
DE60232443D1 (de)	2009-07-09

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Legal Events

Date	Code	Title	Description
2009-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties