ATE144499T1 - 6-(2-hydroxyethylaminoalkyl)-5,11-dioxo-5,6- dihydro-11h- indeno(1,2-c>isochinoline und ihre anwendung als krebsmittel - Google Patents

6-(2-hydroxyethylaminoalkyl)-5,11-dioxo-5,6- dihydro-11h- indeno(1,2-c>isochinoline und ihre anwendung als krebsmittel

Info

Publication number
ATE144499T1
ATE144499T1 AT92920015T AT92920015T ATE144499T1 AT E144499 T1 ATE144499 T1 AT E144499T1 AT 92920015 T AT92920015 T AT 92920015T AT 92920015 T AT92920015 T AT 92920015T AT E144499 T1 ATE144499 T1 AT E144499T1
Authority
AT
Austria
Prior art keywords
indeno
derivatives
dioxo
dihydro
isochinolines
Prior art date
Application number
AT92920015T
Other languages
English (en)
Inventor
Jiri Hrbata
Jiri Krepelka
Milan Melka
Milan Miko
Milan Hruby
Milan Ferenc
Eva Skacelova
Irena Kejhova
Rzena Reichlova
Anna Kargerova
Jitka Sediva
Alois Kolonicny
Josef Urbanec
Jiri Michalsky
Original Assignee
Vufb As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vufb As filed Critical Vufb As
Application granted granted Critical
Publication of ATE144499T1 publication Critical patent/ATE144499T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AT92920015T 1991-08-29 1992-08-27 6-(2-hydroxyethylaminoalkyl)-5,11-dioxo-5,6- dihydro-11h- indeno(1,2-c>isochinoline und ihre anwendung als krebsmittel ATE144499T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS912669A CZ281473B6 (cs) 1991-08-29 1991-08-29 Deriváty 6-/X-(2-hydroxyethyl)aminoalkyl/-5,11 -dioxo-5,6-dihydro-11H-indeno/1,2-c/-isochinolinu a způsob jejich výroby

Publications (1)

Publication Number Publication Date
ATE144499T1 true ATE144499T1 (de) 1996-11-15

Family

ID=5364459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92920015T ATE144499T1 (de) 1991-08-29 1992-08-27 6-(2-hydroxyethylaminoalkyl)-5,11-dioxo-5,6- dihydro-11h- indeno(1,2-c>isochinoline und ihre anwendung als krebsmittel

Country Status (15)

Country Link
EP (1) EP0643699B1 (de)
JP (1) JPH07500581A (de)
AT (1) ATE144499T1 (de)
AU (1) AU663729B2 (de)
CA (1) CA2116680A1 (de)
CZ (1) CZ281473B6 (de)
DE (1) DE69214842T2 (de)
DK (1) DK0643699T3 (de)
FI (1) FI107256B (de)
HU (1) HU217551B (de)
NO (1) NO180194C (de)
PL (1) PL169572B1 (de)
RU (1) RU2120939C1 (de)
SK (1) SK266991A3 (de)
WO (1) WO1993005023A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
AU765135B2 (en) * 1998-10-14 2003-09-11 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Novel indenoisoquinolines as antineoplastic agents
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
EP1603567A4 (de) * 2003-02-28 2006-10-18 Inotek Pharmaceuticals Corp Tetracyclische benzamid-derivate und anwendungsverfahren dafür
US20050228007A1 (en) 2004-02-26 2005-10-13 Prakash Jagtap Isoquinoline derivatives and methods of use thereof
JP2008531562A (ja) 2005-02-25 2008-08-14 イノテック ファーマシューティカルズ コーポレイション 四環アミノ化合物および四環カルボキサミド化合物およびこれらの使用法
CN101316592A (zh) 2005-08-24 2008-12-03 伊诺泰克制药公司 茚并异喹啉酮类似物及其用法
KR20090115879A (ko) 2007-02-28 2009-11-09 이노텍 파마슈티컬스 코포레이션 인데노이소퀴놀리논 유사체와 이의 이용 방법
CN102250000A (zh) * 2010-05-17 2011-11-23 中国人民解放军第二军医大学 茚并喹啉酮类化合物及其制备方法和用途
TWI642658B (zh) * 2017-11-01 2018-12-01 國立臺灣師範大學 茚並異喹啉衍生物的製備方法

Also Published As

Publication number Publication date
FI107256B (fi) 2001-06-29
EP0643699B1 (de) 1996-10-23
AU2583592A (en) 1993-04-05
PL169572B1 (pl) 1996-08-30
DE69214842T2 (de) 1997-02-27
CA2116680A1 (en) 1993-03-18
WO1993005023A1 (en) 1993-03-18
NO940542D0 (no) 1994-02-17
HU217551B (hu) 2000-02-28
FI940895A0 (fi) 1994-02-25
NO180194C (no) 1997-03-05
RU2120939C1 (ru) 1998-10-27
DE69214842D1 (de) 1996-11-28
SK278794B6 (sk) 1998-03-04
AU663729B2 (en) 1995-10-19
CZ266991A3 (en) 1993-03-17
JPH07500581A (ja) 1995-01-19
DK0643699T3 (da) 1997-04-28
NO940542L (no) 1994-02-17
NO180194B (no) 1996-11-25
EP0643699A1 (de) 1995-03-22
HUT70396A (en) 1995-10-30
HU9400563D0 (en) 1994-05-30
SK266991A3 (en) 1998-03-04
FI940895A7 (fi) 1994-02-25
CZ281473B6 (cs) 1996-10-16

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