ATE145132T1 - Therapeutische zusammensetzung und verfahren für ihre herstellung - Google Patents

Therapeutische zusammensetzung und verfahren für ihre herstellung

Info

Publication number
ATE145132T1
ATE145132T1 AT91913139T AT91913139T ATE145132T1 AT E145132 T1 ATE145132 T1 AT E145132T1 AT 91913139 T AT91913139 T AT 91913139T AT 91913139 T AT91913139 T AT 91913139T AT E145132 T1 ATE145132 T1 AT E145132T1
Authority
AT
Austria
Prior art keywords
active substance
pct
cover layer
matrix
colon
Prior art date
Application number
AT91913139T
Other languages
English (en)
Inventor
Peter Edman
Arne Kristensen
Bengt Wideholt
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Application granted granted Critical
Publication of ATE145132T1 publication Critical patent/ATE145132T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91913139T 1990-07-04 1991-07-03 Therapeutische zusammensetzung und verfahren für ihre herstellung ATE145132T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002339A SE9002339L (sv) 1990-07-04 1990-07-04 Terapeutisk komposition och foerfarande foer dess framstaellning

Publications (1)

Publication Number Publication Date
ATE145132T1 true ATE145132T1 (de) 1996-11-15

Family

ID=20379936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913139T ATE145132T1 (de) 1990-07-04 1991-07-03 Therapeutische zusammensetzung und verfahren für ihre herstellung

Country Status (11)

Country Link
US (1) US5505966A (de)
EP (1) EP0610178B1 (de)
JP (1) JPH05508156A (de)
AT (1) ATE145132T1 (de)
AU (1) AU8227291A (de)
DE (1) DE69123159T2 (de)
DK (1) DK0610178T3 (de)
ES (1) ES2094815T3 (de)
GR (1) GR3022337T3 (de)
SE (1) SE9002339L (de)
WO (1) WO1992000732A1 (de)

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DK89592D0 (da) * 1992-07-07 1992-07-07 Helle Broendsted Laegemiddelafgivelsesindretning samt fremgangsmaade til fremstilling deraf
ES2068154B1 (es) * 1993-07-13 1995-11-16 Cantabria Ind Farmaceutica Sa Nuevas formulaciones analgesicas con amplio intervalo de accion.
ES2068762B1 (es) * 1993-07-21 1995-12-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion.
DE4331539A1 (de) * 1993-09-17 1995-03-23 Basf Ag Dextranester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Umhüllung oder Einbettung von Arzneimitteln
WO1995013801A1 (en) * 1993-11-17 1995-05-26 Commonwealth Scientific And Industrial Research Organisation Fatty acid delivery system
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
US5656294A (en) * 1995-06-07 1997-08-12 Cibus Pharmaceutical, Inc. Colonic delivery of drugs
US6231888B1 (en) * 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
AU1751997A (en) * 1996-01-30 1997-08-22 Advanced Polymer Systems Inc. Targeted delivery of drugs to the lower gastrointestinal tract
US6764690B2 (en) * 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
KR100219918B1 (ko) 1997-07-03 1999-09-01 김윤 대장선택적 약물전달용 조성물
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
KR20000011247A (ko) * 1998-07-23 2000-02-25 김윤 다당류를이용한대장선택성약물전달조성물및약학제제
PT1146862E (pt) 1999-01-29 2003-09-30 Disphar Int Bv Composicoes farmaceuticas
CN1285333C (zh) * 2000-06-07 2006-11-22 张昊 结肠定位释放的口服制剂及其制备方法
US6720005B1 (en) 2000-07-07 2004-04-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Coated, platform-generating tablet
EP1174127A1 (de) * 2000-07-21 2002-01-23 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Zuammensetzung zur zielgesteuerten Freigabe eines Wirkstoffs und Verfahren zur Herstellung einer solchen Zusammensetzung
ATE377048T1 (de) 2000-09-06 2007-11-15 Ap Pharma Inc Abbaubare polyacetal-polymere
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US20030152630A1 (en) * 2001-05-11 2003-08-14 Ng Steven Y. PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
US6590059B2 (en) * 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
US6524606B1 (en) * 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
MXPA04006163A (es) * 2001-12-20 2004-11-01 Pharmacia Corp Formas de dosis de liberacion sostenida del orden-cero y metodo de fabricacion de las mismas.
FR2843301B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
FR2843302B1 (fr) 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
CA2501324A1 (en) * 2002-10-30 2004-05-21 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US20070258879A1 (en) * 2005-12-13 2007-11-08 Philip Morris Usa Inc. Carbon beads with multimodal pore size distribution
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
WO2009126742A2 (en) * 2008-04-08 2009-10-15 Appian Labs, Llc Enzyme mediated delivery system
ZA200903858B (en) * 2008-06-19 2013-10-30 Univ Of Witwatesrand Johannesburg Pharmaceutical dosage form
CZ302789B6 (cs) * 2009-11-25 2011-11-09 Zentiva, K. S. Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva
KR20190026648A (ko) * 2016-03-30 2019-03-13 바이탈 베버리지스 글로벌 인크. 선택적 위장관 전달을 위한 조성물 및 방법
WO2024178428A1 (en) * 2023-02-24 2024-08-29 Glanbia Nutritionals, Inc. Shelf stable organic nucleotide compositions and methods of manufacturing the same

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US3959457A (en) * 1970-06-05 1976-05-25 Temple University Microparticulate material and method of making such material
US4024073A (en) * 1972-01-08 1977-05-17 Toray Industries, Inc. Hydrogel and production thereof
US3946110A (en) * 1974-05-30 1976-03-23 Peter, Strong Research And Development Company, Inc. Medicinal compositions and methods of preparing the same
US4042073A (en) * 1976-05-27 1977-08-16 Dana Corporation Disc brake mechanism actuating means
US4507327A (en) * 1983-05-23 1985-03-26 Q.P. Corporation Process for preparing edible products in the form of capsules
US4695463A (en) * 1985-05-24 1987-09-22 Warner-Lambert Company Delivery system for active ingredients and preparation thereof
SE459005B (sv) * 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
DE3601132A1 (de) * 1986-01-16 1987-07-23 Christian Bannert Verfahren zur behandlung der schleimhaut
FR2608456B1 (fr) * 1986-12-18 1993-06-18 Mero Rousselot Satia Microcapsules a base de gelatine et de polysaccharides et leur procede d'obtention
US4915948A (en) * 1987-08-31 1990-04-10 Warner-Lambert Company Tablets having improved bioadhesion to mucous membranes
US4965252A (en) * 1988-06-28 1990-10-23 Hauser-Kuhrts, Inc. Cholesterol-lowering combination compositions of guar gum and niacin
JP2668730B2 (ja) * 1988-03-09 1997-10-27 雪印乳業株式会社 天然ポリマーを用いた徐放性製剤
FR2645439B1 (fr) * 1989-04-07 1991-06-21 Oreal Procede de preparation de capsules d'alginate(s) particulierement adaptees a un usage cosmetique, appareil pour sa mise en oeuvre et composition cosmetique contenant lesdites capsules

Also Published As

Publication number Publication date
DE69123159D1 (de) 1996-12-19
JPH05508156A (ja) 1993-11-18
SE9002339L (sv) 1992-01-05
WO1992000732A1 (en) 1992-01-23
EP0610178A1 (de) 1994-08-17
EP0610178B1 (de) 1996-11-13
ES2094815T3 (es) 1997-02-01
DK0610178T3 (da) 1997-04-14
GR3022337T3 (en) 1997-04-30
US5505966A (en) 1996-04-09
DE69123159T2 (de) 1997-04-10
SE9002339D0 (sv) 1990-07-04
AU8227291A (en) 1992-02-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee