BR0315731A - Comprimidos orais de liberação prolongada e métodos para fabricar e usar os mesmos - Google Patents
Comprimidos orais de liberação prolongada e métodos para fabricar e usar os mesmosInfo
- Publication number
- BR0315731A BR0315731A BR0315731-8A BR0315731A BR0315731A BR 0315731 A BR0315731 A BR 0315731A BR 0315731 A BR0315731 A BR 0315731A BR 0315731 A BR0315731 A BR 0315731A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- present
- manufacturing
- oral
- extended
- Prior art date
Links
- 238000013265 extended release Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000007935 oral tablet Substances 0.000 title 1
- 239000002552 dosage form Substances 0.000 abstract 3
- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 abstract 2
- 229960002227 clindamycin Drugs 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000013268 sustained release Methods 0.000 abstract 2
- 239000012730 sustained-release form Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 208000027136 gram-positive bacterial infections Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPRIMIDOS ORAIS DE LIBERAçãO PROLONGADA E MéTODOS PARA FABRICAR E USAR OS MESMOS". A presente invenção refere-se a formas de dosagem orais para liberação prolongada, incluindo uma forma de dosagem para liberação prolongada independente do pH, de pelo menos um fármaco para um indivíduo. A presente invenção refere-se também a métodos de fabricação e utilização das formas de dosagem para tratar ou prevenir um indivíduo contra várias condições. Também são fornecidas formulações de liberação prolongada específicas de base livre de clindamicina cristalina. As formulações orais de base livre de clindamicina cristalina da presente invenção proporcionam um meio para tratar ou prevenir infecções com bactérias gram-positivas com um número mínimo de tratamentos por dia, potencialmente tão pouco quanto uma vez ou duas vezes ao dia.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42241802P | 2002-10-30 | 2002-10-30 | |
| PCT/US2003/033903 WO2004041244A2 (en) | 2002-10-30 | 2003-10-27 | Oral extended release tablets and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0315731A true BR0315731A (pt) | 2005-09-06 |
Family
ID=32312502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0315731-8A BR0315731A (pt) | 2002-10-30 | 2003-10-27 | Comprimidos orais de liberação prolongada e métodos para fabricar e usar os mesmos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040146556A1 (pt) |
| EP (1) | EP1558211A2 (pt) |
| JP (1) | JP2006507298A (pt) |
| AR (1) | AR041856A1 (pt) |
| AU (1) | AU2003284942A1 (pt) |
| BR (1) | BR0315731A (pt) |
| CA (1) | CA2501324A1 (pt) |
| MX (1) | MXPA05004648A (pt) |
| TW (1) | TW200413032A (pt) |
| WO (1) | WO2004041244A2 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0203296D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| RU2414241C2 (ru) * | 2005-08-26 | 2011-03-20 | БиПиЭсАй ХОЛДИНГЗ, ИНК. | Лекарственные композиции, содержащие гипромеллозные матрицы контролируемого высвобождения |
| US20120251588A1 (en) | 2011-03-30 | 2012-10-04 | Miyuki Fukasawa | Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation |
| US20140302138A1 (en) * | 2011-10-14 | 2014-10-09 | Micro Labs Limited | Extended release pharmaceutical compositions containing carbamazepine |
| EP2790677A4 (en) * | 2011-12-16 | 2015-05-06 | Celanese Eva Performance Polymers Inc | CONTROLLED RELEASE EXCIPIENTS HAVING ARCHITECTURES WITH APPROPRIATE INTERSTITIAL SPACES |
| EP2916828A1 (en) * | 2012-11-07 | 2015-09-16 | Nazura Biohealth Inc. | Gras enteric coating formulations and methods of making and using same |
| JP5836980B2 (ja) * | 2013-01-11 | 2015-12-24 | 信越化学工業株式会社 | 薬物含有粒子、固形製剤及び薬物含有粒子の製造方法 |
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| DE2246013A1 (de) * | 1972-09-20 | 1974-03-28 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von poroesen tabletten |
| GB1456365A (en) * | 1972-10-06 | 1976-11-24 | Gist Brocades Nv | Controlled release composition |
| US4135514A (en) * | 1974-12-23 | 1979-01-23 | Alza Corporation | Osmotic releasing system for administering ophthalmic drug to eye of animal |
| DE2556561C2 (de) * | 1975-12-16 | 1983-04-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von porösen Tabletten |
| JPS6048484B2 (ja) * | 1980-05-20 | 1985-10-28 | アルザ・コ−ポレ−シヨン | 拡散性活性剤デイスペンサ− |
| JPS5758631A (en) * | 1980-09-24 | 1982-04-08 | Toyo Jozo Co Ltd | Coating composition |
| GB8322007D0 (en) * | 1983-08-16 | 1983-09-21 | Wellcome Found | Pharmaceutical delivery system |
| GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| US4892742A (en) * | 1985-11-18 | 1990-01-09 | Hoffmann-La Roche Inc. | Controlled release compositions with zero order release |
| GB8616669D0 (en) * | 1986-07-09 | 1986-08-13 | Merk Sharpe & Dohme Ltd | Pharmaceutical compositions |
| US4880631A (en) * | 1987-09-24 | 1989-11-14 | Merck & Co., Inc. | Controlled porosity osmotic pump |
| US4946686A (en) * | 1987-09-24 | 1990-08-07 | Merck & Co., Inc. | Solubility modulated drug delivery system |
| US4837030A (en) * | 1987-10-06 | 1989-06-06 | American Cyanamid Company | Novel controlled release formulations of tetracycline compounds |
| GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
| US4994273A (en) * | 1987-11-02 | 1991-02-19 | Merck & Co., Inc. | Solubility modulated drug delivery device |
| JPH0791184B2 (ja) * | 1988-03-31 | 1995-10-04 | 田辺製薬株式会社 | 放出制御型製剤およびその製法 |
| FR2633181B1 (fr) * | 1988-06-24 | 1992-01-10 | Glaxo Lab Sa | Composition pharmaceutique a base de ranitidine et son procede de preparation |
| US5175003A (en) * | 1990-04-06 | 1992-12-29 | Biosytes Usa, Inc. | Dual mechanism controlled release system for drug dosage forms |
| IT1246382B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
| US5670170A (en) * | 1990-04-27 | 1997-09-23 | Beecham Group P.L.C. | Pharamaceutical formulation |
| SE9002339L (sv) * | 1990-07-04 | 1992-01-05 | Kabi Pharmacia Ab | Terapeutisk komposition och foerfarande foer dess framstaellning |
| EP0520119A1 (de) * | 1991-06-17 | 1992-12-30 | Spirig Ag Pharmazeutische Präparate | Neue orale Diclofenaczubereitung |
| US5656296A (en) * | 1992-04-29 | 1997-08-12 | Warner-Lambert Company | Dual control sustained release drug delivery systems and methods for preparing same |
| IT1260505B (it) * | 1992-06-01 | 1996-04-09 | Poli Ind Chimica Spa | Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon |
| SE9202250D0 (sv) * | 1992-07-29 | 1992-07-29 | Gacell Lab Ab | Controlled release morphine preparation |
| US5324351A (en) * | 1992-08-13 | 1994-06-28 | Euroceltique | Aqueous dispersions of zein and preparation thereof |
| GB9217295D0 (en) * | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| US5609884A (en) * | 1992-08-31 | 1997-03-11 | G. D. Searle & Co. | Controlled release naproxen sodium plus naproxen combination tablet |
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| US6074669A (en) * | 1997-01-20 | 2000-06-13 | Ranbaxy Laboratories Limited | Controlled drug delivery system for diltiazem |
| US5881388A (en) * | 1998-04-06 | 1999-03-16 | Pratt; Kevin G. | Glove with finger grip inserts |
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| US6150410A (en) * | 1999-02-04 | 2000-11-21 | Abbott Laboratories | pH independent extended release pharmaceutical formulation |
| JP2001055322A (ja) * | 1999-08-18 | 2001-02-27 | Tanabe Seiyaku Co Ltd | パルス放出型製剤 |
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| US20030073648A1 (en) * | 2001-08-28 | 2003-04-17 | Chao Robert S. | Crystaline clindamycin free base |
-
2003
- 2003-10-27 CA CA002501324A patent/CA2501324A1/en not_active Abandoned
- 2003-10-27 WO PCT/US2003/033903 patent/WO2004041244A2/en not_active Ceased
- 2003-10-27 EP EP03779262A patent/EP1558211A2/en not_active Withdrawn
- 2003-10-27 JP JP2004550118A patent/JP2006507298A/ja active Pending
- 2003-10-27 MX MXPA05004648A patent/MXPA05004648A/es not_active Application Discontinuation
- 2003-10-27 BR BR0315731-8A patent/BR0315731A/pt not_active IP Right Cessation
- 2003-10-27 AU AU2003284942A patent/AU2003284942A1/en not_active Abandoned
- 2003-10-29 US US10/696,044 patent/US20040146556A1/en not_active Abandoned
- 2003-10-29 AR ARP030103950A patent/AR041856A1/es unknown
- 2003-10-30 TW TW092130278A patent/TW200413032A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004041244A2 (en) | 2004-05-21 |
| US20040146556A1 (en) | 2004-07-29 |
| TW200413032A (en) | 2004-08-01 |
| JP2006507298A (ja) | 2006-03-02 |
| EP1558211A2 (en) | 2005-08-03 |
| MXPA05004648A (es) | 2005-06-08 |
| AU2003284942A1 (en) | 2004-06-07 |
| WO2004041244A3 (en) | 2004-07-15 |
| AR041856A1 (es) | 2005-06-01 |
| AU2003284942A8 (en) | 2004-06-07 |
| CA2501324A1 (en) | 2004-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A , 6A , E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010. |