ATE145908T1 - 5-triazolo(3,4-i)purinderivate - Google Patents

5-triazolo(3,4-i)purinderivate

Info

Publication number: ATE145908T1
Authority: AT; Austria
Prior art keywords: substituted; triazolo; chem; alkyl; unsubstituted aryl
Prior art date: 1989-09-14

Application number

AT90117662T

Other languages

English (en)

Inventor

Fumio Suzuki

Junichi Shimada

Kenji Ohmori

Haruhiko Manabe

Kazuhiro Kubo

Akira Karasawa

Tetsuji Ohno

Shizuo Shiozaki

Akio Ishii

Katsuichi Shuto

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-14

Filing date

1990-09-13

Publication date

1996-12-15

1990-09-13 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1996-12-15 Application granted granted Critical

1996-12-15 Publication of ATE145908T1 publication Critical patent/ATE145908T1/de

Links

229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
150000003212 purines Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 3
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
239000011593 sulfur Substances 0.000 abstract 2
RLTQUEBNOKLEIN-UHFFFAOYSA-N 9H-[1,2,4]triazolo[3,4-f]purine Chemical class N1=CN2C=NN=C2C2=C1N=CN2 RLTQUEBNOKLEIN-UHFFFAOYSA-N 0.000 abstract 1
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pulmonology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT90117662T 1989-09-14 1990-09-13 5-triazolo(3,4-i)purinderivate ATE145908T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP23911789		1989-09-14
JP26176189		1989-10-06

Publications (1)

Publication Number	Publication Date
ATE145908T1 true ATE145908T1 (de)	1996-12-15

Family

ID=26534087

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90117662T ATE145908T1 (de)	1989-09-14	1990-09-13	5-triazolo(3,4-i)purinderivate

Country Status (8)

Country	Link
EP (1)	EP0417790B1 (de)
JP (1)	JP2980658B2 (de)
AT (1)	ATE145908T1 (de)
CA (1)	CA2025413C (de)
DE (1)	DE69029303T2 (de)
DK (1)	DK0417790T3 (de)
ES (1)	ES2097124T3 (de)
GR (1)	GR3022027T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5338743A (en) *	1988-06-06	1994-08-16	Fujisawa Pharmaceutical Co., Ltd.	New use of the adenosine antagonist
CA2028235C (en) *	1989-10-20	1997-01-21	Fumio Suzuki	Condensed purine derivatives
US5922751A (en)	1994-06-24	1999-07-13	Euro-Celtique, S.A.	Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
JPH10508032A (ja)	1994-12-13	1998-08-04	ユーロ−セルティーク，エス．エイ．	アリールチオキサンチン類
US6075016A (en)	1996-04-10	2000-06-13	Euro-Celtique S.A.	6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en)	1996-06-06	1999-01-26	Euro-Celtique, S.A.	Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
ES2166270B1 (es) *	1999-07-27	2003-04-01	Almirall Prodesfarma Sa	Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona.
US7511050B2 (en) *	2006-06-23	2009-03-31	Incyte Corporation	Purinone derivatives as HM74A agonists
AR061626A1 (es) *	2006-06-23	2008-09-10	Incyte Corp	Derivados de purinona como agonistas de hm74a
AU2019205661B2 (en)	2018-01-04	2022-06-30	Impetis Biosciences Ltd.	Tricyclic compounds, compositions and medicinal applications thereof
JP7280883B2 (ja) *	2018-08-30	2023-05-24	テラ・ストーン株式会社	キサンチンオキシダーゼを阻害するためのヒドラジノプリン化合物及びトリアゾロプリン化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4404380A (en) *	1977-02-14	1983-09-13	Mead Johnson & Company	Triazolopyrimidines

1990
- 1990-09-13 JP JP2243248A patent/JP2980658B2/ja not_active Expired - Lifetime
- 1990-09-13 AT AT90117662T patent/ATE145908T1/de not_active IP Right Cessation
- 1990-09-13 EP EP90117662A patent/EP0417790B1/de not_active Expired - Lifetime
- 1990-09-13 DK DK90117662.8T patent/DK0417790T3/da active
- 1990-09-13 DE DE69029303T patent/DE69029303T2/de not_active Expired - Fee Related
- 1990-09-13 ES ES90117662T patent/ES2097124T3/es not_active Expired - Lifetime
- 1990-09-14 CA CA002025413A patent/CA2025413C/en not_active Expired - Fee Related
1996
- 1996-12-13 GR GR960403448T patent/GR3022027T3/el unknown

Also Published As

Publication number	Publication date
EP0417790A3 (en)	1992-03-18
JP2980658B2 (ja)	1999-11-22
ES2097124T3 (es)	1997-04-01
CA2025413C (en)	1997-11-04
DE69029303D1 (de)	1997-01-16
GR3022027T3 (en)	1997-03-31
CA2025413A1 (en)	1991-03-15
EP0417790B1 (de)	1996-12-04
DK0417790T3 (da)	1997-04-07
EP0417790A2 (de)	1991-03-20
JPH03204879A (ja)	1991-09-06
DE69029303T2 (de)	1997-05-28

Legal Events

Date	Code	Title	Description
1997-06-15	UEP	Publication of translation of european patent specification
2002-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69321525D1 (de)	1998-11-19	Morphinan-derivate und medizinische verwendung
GR3020848T3 (en)	1996-11-30	1,8-Naphthyridin-2-one derivatives
ATE195739T1 (de)	2000-09-15	Kondensierte purinderivate
DK0976748T3 (da)	2004-03-22	Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
DK0417790T3 (da)	1997-04-07	S-triazolo(3,4-i)purin-derivater
DE69725585D1 (de)	2003-11-20	Phenylalkylcarbonsäure-derivate
NO921159L (no)	1992-09-28	Tiazolidinon- og oksazolidinonderivater, fremgangsmaate til fremstilling derav, samt anvendelse av derivatene som vasodilatorer
AU8003594A (en)	1995-05-22	Quinolinecarboxylic acid derivative and salt thereof
DK0541322T3 (da)	1996-10-14	1-Alkyl-2-acyl-1,2-disulfonylhydraziner med antineoplastisk aktivitet
AU659922B2 (en)	1995-06-01	Anti-ulcer pyridyloxy derivatives, their preparation and uses
DK424888A (da)	1989-02-01	Naphthothiazepinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende saadanne derivater
ATE83233T1 (de)	1992-12-15	Ethanon-oxime.
DE3479421D1 (de)	1989-09-21	Dibenzopyran derivatives