ATE147613T1 - Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse - Google Patents

Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse

Info

Publication number
ATE147613T1
ATE147613T1 AT90914884T AT90914884T ATE147613T1 AT E147613 T1 ATE147613 T1 AT E147613T1 AT 90914884 T AT90914884 T AT 90914884T AT 90914884 T AT90914884 T AT 90914884T AT E147613 T1 ATE147613 T1 AT E147613T1
Authority
AT
Austria
Prior art keywords
growth
attachment
epithelial cells
prosthetical
synthetic material
Prior art date
Application number
AT90914884T
Other languages
English (en)
Inventor
Cary Reich
Jeffrey Forsberg
Harold Levy
Jean Toner-Webb
Original Assignee
Chiron Vision Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Vision Corp filed Critical Chiron Vision Corp
Application granted granted Critical
Publication of ATE147613T1 publication Critical patent/ATE147613T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C12N2537/10—Cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Eyeglasses (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
AT90914884T 1989-09-15 1990-09-05 Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse ATE147613T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40805989A 1989-09-15 1989-09-15

Publications (1)

Publication Number Publication Date
ATE147613T1 true ATE147613T1 (de) 1997-02-15

Family

ID=23614695

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90914884T ATE147613T1 (de) 1989-09-15 1990-09-05 Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse

Country Status (9)

Country Link
US (1) US6090995A (de)
EP (1) EP0491860B1 (de)
JP (1) JPH05501971A (de)
KR (1) KR920702975A (de)
AT (1) ATE147613T1 (de)
BR (1) BR9007643A (de)
CA (1) CA2066660C (de)
DE (1) DE69029735T2 (de)
WO (1) WO1991003990A1 (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0601055T3 (da) * 1991-08-16 2000-10-02 Joseph C Salamone Medikamentovertrukket brydende okulært forkammerimplantat
JP3455217B2 (ja) * 1992-02-13 2003-10-14 バイオ−メトリック システムズ インコーポレイテッド 架橋マトリックス中の化学種の固定
DE69434617D1 (de) * 1993-11-19 2006-04-06 Univ Sydney Verfahren zur prophylaxe oder kontrolle des katarakts
TW257671B (de) * 1993-11-19 1995-09-21 Ciba Geigy
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
DE19505070C2 (de) * 1995-02-15 1997-03-27 Axel Prof Dr Med Haverich Künstliche Gefäßsysteme und Verfahren zu ihrer Herstellung
US20020095218A1 (en) * 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
PT1019111E (pt) 1998-04-27 2002-10-31 Surmodics Inc Revestimento que liberta um agente bioactivo
ATE424147T1 (de) * 1998-06-05 2009-03-15 Organogenesis Inc Biotechnisch erzeugte gefässprothese für die implantation
WO1999062427A1 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered vascular graft support prostheses
EP1082071B1 (de) * 1998-06-05 2009-03-04 Organogenesis Inc. Verfahren zur herstellung einer gefässprothese
WO1999062424A2 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered tubular graft prostheses
AU1075701A (en) 1999-10-08 2001-04-23 Protogene Laboratories, Inc. Method and apparatus for performing large numbers of reactions using array assembly
BR0000016A (pt) * 2000-01-06 2001-08-14 Ferrara Ophthalmics Ltda Dispositivo para implante intracorneano e processo para tratamento de deformidades da córnea
CA2408172A1 (en) * 2000-05-16 2001-11-22 Peter Supronowicz Electrically conducting nanocomposite materials for biomedical applications
EP1320390A2 (de) * 2000-09-18 2003-06-25 Organogenesis Inc. Bioartifizielle flache schichtförmige prothesen und ihre verwendung
AU2002226276A1 (en) * 2000-11-30 2002-06-11 Aachener Centrum Fur Technologietransfer In Der Ophthalmologie E.V. Keratoprothesis
JP4043789B2 (ja) * 2001-01-24 2008-02-06 ノバルティス アクチエンゲゼルシャフト 表面を修飾するための方法
US20050064012A1 (en) * 2001-07-17 2005-03-24 Baylor College Of Medicine Process for causing myopic shift in vision
US6444318B1 (en) 2001-07-17 2002-09-03 Surmodics, Inc. Self assembling monolayer compositions
US20030018382A1 (en) * 2001-07-17 2003-01-23 Pflugfelder Stephen C. Process for improving vision
US7348055B2 (en) 2001-12-21 2008-03-25 Surmodics, Inc. Reagent and method for providing coatings on surfaces
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
CN101134119A (zh) 2002-05-24 2008-03-05 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
EP1549255A4 (de) * 2002-09-13 2007-12-19 Coopervision Inc Vorrichtungen und verfahren zur verbesserung der sehstärke
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
WO2005028629A2 (en) * 2003-09-19 2005-03-31 Applera Corporation Whole genome expression analysis system
US20050226771A1 (en) * 2003-09-19 2005-10-13 Lehto Dennis A High speed microplate transfer
US20050233472A1 (en) * 2003-09-19 2005-10-20 Kao H P Spotting high density plate using a banded format
US20050158356A1 (en) * 2003-11-20 2005-07-21 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
CN1964749A (zh) 2004-04-06 2007-05-16 苏莫迪克斯公司 用于生物活性剂的涂料组合物
BRPI0511339A (pt) 2004-05-20 2007-12-04 Coopervision Inc revestimentos córneos e correção de aberração de frente de onda para melhorar a visão
US20050281858A1 (en) * 2004-06-18 2005-12-22 Kloke Tim M Devices, articles, coatings, and methods for controlled active agent release
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
EP1904118B1 (de) * 2005-07-20 2018-01-17 Surmodics, Inc. Polymerbeschichtungen und verfahren zur zellanhaftung
EP1937796A2 (de) * 2005-07-20 2008-07-02 SurModics, Inc. Polymerbeschichtete nanofibrillenstrukturen und verfahren zur zellhaltung und -differenzierung
CN1903144A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工韧带及其制备方法
CN1903143A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工血管及其制备方法
CN100482178C (zh) * 2005-08-04 2009-04-29 广东冠昊生物科技有限公司 带生物膜的血管瘤夹
EP2535041A1 (de) * 2005-09-09 2012-12-19 Ottawa Health Research Institute Durchdringende Netzwerke und dazugehörige Verfahren und Zusammensetzung
CN1985778B (zh) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 生物型人工角膜
CN1986006A (zh) 2005-12-20 2007-06-27 广州知光生物科技有限公司 生物型神经导管
CN1986001B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物护创膜
CN1986007B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物型外科补片
US20070218038A1 (en) 2006-03-17 2007-09-20 Pegasus Biologics, Inc. Stabilized, sterilized collagen scaffolds with active adjuncts attached
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
US8652564B2 (en) * 2006-05-08 2014-02-18 The Ohio State University Research Foundation Aminated materials for assays
CN101332314B (zh) * 2008-07-22 2012-11-14 广东冠昊生物科技股份有限公司 生物型关节软骨修补件
US20100023129A1 (en) * 2008-07-22 2010-01-28 Guo-Feng Xu Jawbone prosthesis and method of manufacture
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
US20080075753A1 (en) * 2006-09-25 2008-03-27 Chappa Ralph A Multi-layered coatings and methods for controlling elution of active agents
WO2009023276A1 (en) * 2007-08-15 2009-02-19 The Board Of Trustees Of The Leland Stanford Junior University Sequential coupling of biomolecule layers to polymers
KR101683042B1 (ko) 2008-04-04 2016-12-06 포사이트 비젼4, 인크. 통증 관리 및 시력을 위한 치료 장치
US9498385B2 (en) 2009-10-23 2016-11-22 Nexisvision, Inc. Conformable therapeutic shield for vision and pain
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
JP2011245053A (ja) * 2010-05-27 2011-12-08 Nanyang Technological Univ 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
EP2535062A1 (de) * 2011-06-13 2012-12-19 Dentsply IH AB Mit Kollagen beschichteter Artikel
US9295531B2 (en) 2011-06-13 2016-03-29 Dentsply International Inc. Collagen coated article
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン， インコーポレイテッド 屈折矯正のためのコンタクトレンズ
JP2015077452A (ja) * 2014-12-25 2015-04-23 ナンヤン テクノロジカル ユニヴァーシティー 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物
WO2017221045A1 (en) * 2016-06-24 2017-12-28 Centre National De La Recherche Scientifique (Cnrs) Surface-modified polymeric implantable substrates grafted with a properties-imparting compound using clip chemistry
JP6338715B2 (ja) * 2017-02-06 2018-06-06 ナンヤン テクノロジカル ユニヴァーシティー 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物
WO2022086756A1 (en) 2020-10-19 2022-04-28 Journey1, Inc. Astigmatism correcting contact lenses
US20240139382A1 (en) * 2021-03-02 2024-05-02 Toray Industries, Inc. Coated medical device and production method therefor

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2714721A (en) * 1953-01-23 1955-08-09 Jr William Stone Artificial corneal implants
US2952023A (en) * 1957-03-19 1960-09-13 Rosen Hyman Corneal fabrication
US3454966A (en) * 1965-02-11 1969-07-15 Hyman Rosen Prosthetic corneal fabrication with heating and cooling means to facilitate attachment to corneal tissue
US3438374A (en) * 1966-02-28 1969-04-15 Us Health Education & Welfare Method of bonding tissue surfaces and controlling hemorrhaging thereof using a tissue adhesive and hemostatic composition
US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US3959078A (en) * 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
JPS5338111B2 (de) * 1974-11-14 1978-10-13
SU700125A1 (ru) * 1975-03-17 1979-11-30 Свердловский государственный медицинский институт Способ соединени краев проникающей раны роговицы
SU544429A1 (ru) * 1975-12-08 1977-01-30 Всесоюзный Научно-Исследовательский Институт Глазных Болезней Биологический клей
DE2705234A1 (de) * 1977-02-08 1978-08-17 Hennig Gerhard Keratoprothese
US4126904A (en) * 1977-03-31 1978-11-28 Shepard Dennis D Artificial lens and method of locating on the cornea
US4189546A (en) * 1977-07-25 1980-02-19 Bausch & Lomb Incorporated Polysiloxane shaped article for use in biomedical applications
US4240163A (en) * 1979-01-31 1980-12-23 Galin Miles A Medicament coated intraocular lens
US4223984A (en) * 1979-04-04 1980-09-23 Opticol Corporation Collagen soft contact lens
US4346482A (en) * 1981-01-22 1982-08-31 Tennant Jerald L Living contact lens
US4452235A (en) * 1982-01-04 1984-06-05 Reynolds Alvin E Method for corneal curvature adjustment
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
US4614517A (en) * 1982-08-04 1986-09-30 La Jolla Cancer Research Foundation Tetrapeptide
US4589881A (en) * 1982-08-04 1986-05-20 La Jolla Cancer Research Foundation Polypeptide
US4722906A (en) * 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
DE3241589A1 (de) * 1982-11-10 1984-05-17 Pfaudler-Werke Ag, 6830 Schwetzingen Implantate und verfahren zu deren herstellung
US4656083A (en) * 1983-08-01 1987-04-07 Washington Research Foundation Plasma gas discharge treatment for improving the biocompatibility of biomaterials
JPS60197736A (ja) * 1984-03-21 1985-10-07 Nitto Electric Ind Co Ltd 多孔質薄葉材料の接着方法
JPS60221755A (ja) * 1984-04-18 1985-11-06 Nippon Kayaku Co Ltd 基材表面皮膜の染色法
US4959074A (en) * 1984-08-23 1990-09-25 Gergory Halpern Method of hydrophilic coating of plastics
US4624669A (en) * 1984-09-26 1986-11-25 Surgidev Corporation Corneal inlay with holes
NO166836C (no) * 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
US4676790A (en) * 1985-09-25 1987-06-30 Kern Seymour P Method of manufacture and implantation of corneal inlays
US4919659A (en) * 1985-12-16 1990-04-24 The Board Of Regents For The University Of Washington Radio frequency plasma deposited polymers that enhance cell growth
US4662881A (en) * 1986-01-21 1987-05-05 Nordan Lee T Epikeratophakia process
US4836884A (en) * 1986-02-17 1989-06-06 Telectronics N.V. Implantable materials
DE3778195D1 (de) * 1986-04-07 1992-05-21 Agency Ind Science Techn Antithrombogenisches material.
US4799931A (en) * 1986-05-14 1989-01-24 Lindstrom Richard L Intracorneal lens
US4772283A (en) * 1986-05-16 1988-09-20 White Thomas C Corneal implant
US4715858A (en) * 1986-07-25 1987-12-29 Lindstrom Richard L Epicorneal lens
US4983181A (en) * 1986-10-16 1991-01-08 Cbs Lens, Collagen hydrogel for promoting epithelial cell growth and artificial lens using the same
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
DE3637260A1 (de) * 1986-11-03 1988-05-11 Max Planck Gesellschaft Verfahren zur besiedlung von oberflaechen mit endothelzellen
US4782027A (en) * 1987-01-22 1988-11-01 President And Fellows Of Harvard College Protein detection by negative staining
US5094876A (en) * 1987-04-10 1992-03-10 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
DE3788062D1 (de) * 1987-05-12 1993-12-09 Christian Dr Med Mittermayer Verfahren zur Besiedlung einer Polymeroberfläche mit menschlichen Gefässinnenhautzellen.
US4839464A (en) * 1987-08-25 1989-06-13 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5091206A (en) * 1987-10-26 1992-02-25 Baxter Diagnostics Inc. Process for producing magnetically responsive polymer particles and application thereof
JPH02502261A (ja) * 1987-11-09 1990-07-26 チロン・オフサルミックス・インコーポレイテッド 人工器官デバイスの移植
CA1335721C (en) * 1987-12-24 1995-05-30 Patrick E. Guire Biomolecule attached to a solid surface by means of a spacer and methods of attaching biomolecules to surfaces
US4976733A (en) * 1988-02-03 1990-12-11 Biomedical Design, Inc. Prevention of prosthesis calcification
JP2772087B2 (ja) * 1988-02-03 1998-07-02 バイオメディカル・デザイン・インコーポレーテッド 補綴材のカルシウム沈着の防止
JPH01300959A (ja) * 1988-05-31 1989-12-05 Canon Inc 表面機能性膜を有する眼内レンズ
EP0425485B1 (de) * 1988-07-22 2000-10-04 SurModics, Inc. Herstellung von polymeren oberflächen
US5080924A (en) * 1989-04-24 1992-01-14 Drexel University Method of making biocompatible, surface modified materials
US5414075A (en) * 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification

Also Published As

Publication number Publication date
CA2066660C (en) 2002-07-30
KR920702975A (ko) 1992-12-17
US6090995A (en) 2000-07-18
WO1991003990A1 (en) 1991-04-04
BR9007643A (pt) 1992-08-18
EP0491860B1 (de) 1997-01-15
CA2066660A1 (en) 1991-03-16
DE69029735D1 (de) 1997-02-27
EP0491860A4 (en) 1993-06-30
DE69029735T2 (de) 1997-07-31
JPH05501971A (ja) 1993-04-15
EP0491860A1 (de) 1992-07-01

Similar Documents

Publication Publication Date Title
DE69029735D1 (de) Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse
ATE88879T1 (de) Implantierung von protheseanordnungen.
RU94045951A (ru) Покровный материал и способ его получения, имплантант для биомедицинского использования
DK0484401T3 (da) Fremstilling af vaskulær endothelcellevækstfaktor
ATE4440T1 (de) Vorrichtung zur behandlung von beschaedigten oberflaechen menschlicher gelenke.
SE8505518D0 (sv) Implantationslins, forfarande for framsstellning derav och anordning for att utfora forfarandet
DE69814950D1 (de) Mit Hydroxyapatit beschichtete Prothesenimplantate und Verfahren zur Behandlung von Prothesenimplantaten die mit Hydroxyapatit plasmagespritzt sind
DE69717519D1 (de) Verfahren zur Herstellung von biologischem Implantationsmaterial
WO1999026674A3 (de) Verfahren zur immobilisierung von mediatormolekülen auf anorganischen und metallischen implantatmaterialien
SE9201128D0 (sv) Artificial filling and prosthetic material
PT98889A (pt) Processo para a preparacao de material para proteses osseas a base de produtos ceramicos osseos
DE69132918D1 (de) Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung
ATE222782T1 (de) Biomaterial und implantat zur reparatur und ersatz von knochen
FR2693650B1 (fr) Implant pour le remplacement partiel ou total d'organes de préférence cartilagineux ou osseux.
DE3484933D1 (de) Implantat zur befestigung von zahnprothesen.
ES2173946T3 (es) Materiales conformados a partir de particulas oseas de forma alargada y procedimiento de preparacion de estos materiales.
ATE86129T1 (de) Implantat.
DE59608548D1 (de) Vorrichtung zur geregelten Dispergierbehandlung von hochkonsistentem Faserstoff
DE3868910D1 (de) Implantat zur befestigung von zahnprothesen.
AU4460089A (en) Reflector material for artificial light source
ES2123582T3 (es) Proteina con capacidad de formacion de huesos y procedimiento para su produccion.
DE59008850D1 (de) Verfahren zur Herstellung von Brustprothesen.
FR2415456A1 (fr) Implant pour protheses
FR2652496B1 (fr) Support pour implantation de protheses valvulaires cardiaques.
DK1240908T3 (da) Flerkomponentmateriale og fremgangsmåde til fremstilling af dette

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties