ATE148126T1 - Inhibitoren für glykosaminosyl-transferase-v - Google Patents

Inhibitoren für glykosaminosyl-transferase-v

Info

Publication number
ATE148126T1
ATE148126T1 AT90901253T AT90901253T ATE148126T1 AT E148126 T1 ATE148126 T1 AT E148126T1 AT 90901253 T AT90901253 T AT 90901253T AT 90901253 T AT90901253 T AT 90901253T AT E148126 T1 ATE148126 T1 AT E148126T1
Authority
AT
Austria
Prior art keywords
inhibitors
glycosaminosyl
transferase
acceptors
cells
Prior art date
Application number
AT90901253T
Other languages
English (en)
Inventor
James Michael Pierce
Ole Hindsgaul
Original Assignee
Alberta Res Council
James Michael Pierce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alberta Res Council, James Michael Pierce filed Critical Alberta Res Council
Application granted granted Critical
Publication of ATE148126T1 publication Critical patent/ATE148126T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT90901253T 1988-11-21 1989-11-21 Inhibitoren für glykosaminosyl-transferase-v ATE148126T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/274,069 US5032505A (en) 1988-11-21 1988-11-21 Inhibitors for glycosaminosyl transferase V

Publications (1)

Publication Number Publication Date
ATE148126T1 true ATE148126T1 (de) 1997-02-15

Family

ID=23046623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90901253T ATE148126T1 (de) 1988-11-21 1989-11-21 Inhibitoren für glykosaminosyl-transferase-v

Country Status (8)

Country Link
US (1) US5032505A (de)
EP (1) EP0593419B1 (de)
JP (1) JPH04502010A (de)
AT (1) ATE148126T1 (de)
AU (1) AU4741690A (de)
CA (1) CA2003537A1 (de)
DE (1) DE68927718D1 (de)
WO (1) WO1990005527A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206356A (en) * 1988-11-21 1993-04-27 Chembiomed, Ltd. Inhibitors for alpha-L-fucosyl transferase
KR940000166B1 (ko) * 1989-11-09 1994-01-08 니혼다바고 상교오 가부시기가이샤 신규 글루코사민 유도체 및 이것을 막 구성성분으로서 함유한 리포솜
DE4009630C2 (de) * 1990-03-26 1995-09-28 Reinhard Prof Dr Dr Brossmer CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
WO1991016332A1 (en) * 1990-04-12 1991-10-31 Japan Tobacco Inc. 4,6-o-hydroxyphosphorylglucosamine derivative
AU660641B2 (en) * 1991-01-10 1995-07-06 Merrell Dow Pharmaceuticals Inc. Novel glucohydrolase inhibitors useful as antidiabetic agents
US5352670A (en) * 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
US5220008A (en) * 1991-11-22 1993-06-15 E. I. Du Pont De Nemours And Company Oligosaccharide inhibitors for influenza virus
US5620864A (en) * 1992-06-29 1997-04-15 Health Research, Inc. Acceptor for fucosyl transferase
US6756361B1 (en) * 1997-10-14 2004-06-29 Nabi Enterococcus antigens and vaccines
US6897052B1 (en) * 1998-08-07 2005-05-24 Glycodesign Holdings Ltd. N-acetylglycosaminyl transferase genes
US20050026866A1 (en) * 2002-08-02 2005-02-03 Pawelek John M. Agents and methods for treatment of disease by oligosaccharide targeting agents
WO2005044861A1 (en) * 2003-10-31 2005-05-19 Wyeth Holdings Corporation Polysaccharides of helicobacter pylori
EP2411526A4 (de) * 2009-03-27 2012-09-19 Zacharon Pharmaceuticals Inc Modulatoren der gangliosidenbiosynthese

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4770994A (en) * 1982-07-30 1988-09-13 Abbott Laboratories Determination of carbohydrate acceptors
DE3380452D1 (en) * 1983-09-08 1989-09-28 Abbott Lab Determination of carbohydrate acceptors
JPS63152998A (ja) * 1986-12-16 1988-06-25 Konica Corp 糖転移酵素の測定方法
JPS6442496A (en) * 1987-08-10 1989-02-14 Wako Pure Chem Ind Ltd Activity measurement for tansglycosidase
JP2579497B2 (ja) * 1987-09-07 1997-02-05 オリエンタル酵母工業株式会社 肝臓疾患診断剤

Also Published As

Publication number Publication date
EP0593419A4 (en) 1994-08-17
WO1990005527A1 (en) 1990-05-31
DE68927718D1 (de) 1997-03-06
AU4741690A (en) 1990-06-12
US5032505A (en) 1991-07-16
JPH04502010A (ja) 1992-04-09
EP0593419B1 (de) 1997-01-22
EP0593419A1 (de) 1994-04-27
CA2003537A1 (en) 1990-05-21

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