ATE14983T1 - Co- und terpolymere von alkyl- und chloroalkylvinylaethern, maleinsaeureanhydrid und maleinsaeureimid mit antitumor-wirksamkeit. - Google Patents
Co- und terpolymere von alkyl- und chloroalkylvinylaethern, maleinsaeureanhydrid und maleinsaeureimid mit antitumor-wirksamkeit.Info
- Publication number
- ATE14983T1 ATE14983T1 AT82303087T AT82303087T ATE14983T1 AT E14983 T1 ATE14983 T1 AT E14983T1 AT 82303087 T AT82303087 T AT 82303087T AT 82303087 T AT82303087 T AT 82303087T AT E14983 T1 ATE14983 T1 AT E14983T1
- Authority
- AT
- Austria
- Prior art keywords
- maleic acid
- antitumor activity
- ter
- ethers
- polymers
- Prior art date
Links
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 title abstract 3
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- 150000002170 ethers Chemical class 0.000 title 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 title 1
- 239000011976 maleic acid Substances 0.000 title 1
- 229920001897 terpolymer Polymers 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical class C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 125000005462 imide group Chemical group 0.000 abstract 1
- 125000005439 maleimidyl group Chemical group C1(C=CC(N1*)=O)=O 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Indole Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27459681A | 1981-06-17 | 1981-06-17 | |
| EP82303087A EP0067707B1 (de) | 1981-06-17 | 1982-06-15 | Co- und Terpolymere von Alkyl- und Chloroalkylvinyläthern, Maleinsäureanhydrid und Maleinsäureimid mit Antitumor-Wirksamkeit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE14983T1 true ATE14983T1 (de) | 1985-09-15 |
Family
ID=23048853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82303087T ATE14983T1 (de) | 1981-06-17 | 1982-06-15 | Co- und terpolymere von alkyl- und chloroalkylvinylaethern, maleinsaeureanhydrid und maleinsaeureimid mit antitumor-wirksamkeit. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0067707B1 (de) |
| JP (1) | JPS57212120A (de) |
| AT (1) | ATE14983T1 (de) |
| AU (1) | AU548298B2 (de) |
| CA (1) | CA1191145A (de) |
| DE (1) | DE3265603D1 (de) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3224943A (en) * | 1964-03-06 | 1965-12-21 | Hercules Powder Co Ltd | Process for retarding the growth of tumors |
| JPS5399334A (en) * | 1977-02-08 | 1978-08-30 | Bayer Ag | Antiitumor agent |
| US4265879A (en) * | 1977-09-13 | 1981-05-05 | Monsanto Company | Method for controlling blood triglycerides |
| JPS5740874A (en) * | 1980-08-22 | 1982-03-06 | Shinetsu Polymer Co | Pressure contact holding type connector |
| US4397995A (en) * | 1980-12-29 | 1983-08-09 | Monsanto Company | Polymeric anti-tumor agent and method of preparation |
-
1982
- 1982-06-15 AT AT82303087T patent/ATE14983T1/de active
- 1982-06-15 EP EP82303087A patent/EP0067707B1/de not_active Expired
- 1982-06-15 DE DE8282303087T patent/DE3265603D1/de not_active Expired
- 1982-06-16 CA CA000405253A patent/CA1191145A/en not_active Expired
- 1982-06-16 AU AU84921/82A patent/AU548298B2/en not_active Ceased
- 1982-06-16 JP JP57102334A patent/JPS57212120A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS57212120A (en) | 1982-12-27 |
| JPH0376324B2 (de) | 1991-12-05 |
| AU8492182A (en) | 1983-12-22 |
| EP0067707A3 (en) | 1983-03-23 |
| DE3265603D1 (en) | 1985-09-26 |
| EP0067707A2 (de) | 1982-12-22 |
| AU548298B2 (en) | 1985-12-05 |
| CA1191145A (en) | 1985-07-30 |
| EP0067707B1 (de) | 1985-08-21 |
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