ATE150176T1 - Chromatographisches material - Google Patents

Chromatographisches material

Info

Publication number
ATE150176T1
ATE150176T1 AT88305217T AT88305217T ATE150176T1 AT E150176 T1 ATE150176 T1 AT E150176T1 AT 88305217 T AT88305217 T AT 88305217T AT 88305217 T AT88305217 T AT 88305217T AT E150176 T1 ATE150176 T1 AT E150176T1
Authority
AT
Austria
Prior art keywords
chromatographic material
stable
general formula
solid support
group
Prior art date
Application number
AT88305217T
Other languages
English (en)
Inventor
Richard Frederick Hammen
Original Assignee
Chromatochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromatochem Inc filed Critical Chromatochem Inc
Application granted granted Critical
Publication of ATE150176T1 publication Critical patent/ATE150176T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
AT88305217T 1987-06-08 1988-06-08 Chromatographisches material ATE150176T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5898887A 1987-06-08 1987-06-08
US18776588A 1988-04-29 1988-04-29

Publications (1)

Publication Number Publication Date
ATE150176T1 true ATE150176T1 (de) 1997-03-15

Family

ID=26738237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88305217T ATE150176T1 (de) 1987-06-08 1988-06-08 Chromatographisches material

Country Status (5)

Country Link
EP (1) EP0295073B1 (de)
JP (1) JPH0769316B2 (de)
AT (1) ATE150176T1 (de)
CA (1) CA1320718C (de)
DE (1) DE3855816T2 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
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CA1335721C (en) * 1987-12-24 1995-05-30 Patrick E. Guire Biomolecule attached to a solid surface by means of a spacer and methods of attaching biomolecules to surfaces
GB8902770D0 (en) * 1989-02-08 1989-03-30 Bioprocessing Ltd Improvements in or relating to supports for immunoaffinity separations
CA1332598C (en) * 1989-06-20 1994-10-18 Laura J. Crane Polyethyleneimine matrixes for affinity chromatography
ATE102074T1 (de) * 1989-09-29 1994-03-15 Rohm & Haas Ligand enthaltendes medium fuer chromatographische trennung, verfahren zur dessen herstellung und dessen verwendung zur isolierung von synthetischen oder natuerlichen molekuelen von einer fluidmischung.
WO1992010508A1 (fr) * 1990-12-06 1992-06-25 Sumitomo Electric Industries, Ltd. Procede de separation de proteines et appareil utilise a cet effet
DE4039677A1 (de) * 1990-12-12 1992-06-17 Boehringer Mannheim Gmbh Universalbindefilm
US5763191A (en) * 1990-12-12 1998-06-09 Boehringer Mannheim Gmbh Universal binding film
US5354461A (en) * 1991-02-20 1994-10-11 Eisai Co., Ltd. Packings combining protein to a support via a spacer
CA2061519C (en) * 1991-02-20 2004-05-18 Naoki Asakawa Packings combining protein to a support via a spacer
DE4217917A1 (de) * 1992-05-30 1993-12-02 Job Prof Dr Med Harenberg Immobilisation von chemisch kovalent gebundenem Heparin an Polymere mit Arylresten im Polymer
JP2871435B2 (ja) * 1993-04-22 1999-03-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 親水性ポリマー被覆パーフルオロカーボンポリマーベースのマトリックスの製造方法
US5910462A (en) * 1993-07-28 1999-06-08 Gani; Mary Susan Jean Zirconia particles
JPH09501719A (ja) * 1993-08-19 1997-02-18 ミネソタ マイニング アンド マニュファクチャリング カンパニー ヘパリン官能アフィニティー支持体
DE4333674A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Nukleotidhaltiges Sorbens für die Affinitätschromatographie
CN1057608C (zh) * 1995-12-04 2000-10-18 广州市博普生物技术有限公司 一种亲和层析材料及制备方法和应用
CN1057607C (zh) * 1995-12-04 2000-10-18 广州市博普生物技术有限公司 一种双功能层析材料及制备方法和应用
US5789578A (en) * 1996-01-11 1998-08-04 Massey University Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality
JPH1045601A (ja) * 1996-08-08 1998-02-17 Mitsuru Akashi 抗ウイルス素材
WO1998041534A2 (en) * 1997-03-19 1998-09-24 Biosepra Inc. Multifunctional ceramic particles as supports for solid phase and combinatorial synthesis
FR2785200B1 (fr) * 1998-10-30 2001-03-30 Centre Nat Rech Scient Utilisation d'un gel adsorbant pour eliminer et purifier les biomolecules
US6306665B1 (en) * 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
EP1255603A1 (de) * 2000-02-09 2002-11-13 RESQ Lab B.V. Packungsmaterial für die trennung von biomolekülen
US6802966B2 (en) * 2001-08-14 2004-10-12 W. R. Grace & Co. Conn. Solid compositions for selective adsorption from complex mixtures
SE526038C2 (sv) * 2002-07-08 2005-06-21 Gambro Lundia Ab Polymeraffinitetsmatris, förfarande för framställning därav och anvädning därav
GB0319604D0 (en) * 2003-08-20 2003-09-24 Wivenhoe Technology Ltd Immobilization matrix for peptides and proteins
WO2005119255A2 (en) * 2004-05-12 2005-12-15 Applera Corporation Constrained cis-diol-borate bioconjugation system
US20060121501A1 (en) * 2004-10-22 2006-06-08 Stanislaw Burzynski Method for immobilizing molecular probes to a semiconductor oxide surface
US20080220968A1 (en) 2005-07-05 2008-09-11 Ge Healthcare Bio-Sciences Ab [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
US7491669B2 (en) * 2006-02-07 2009-02-17 Crystal Clear Technologies, Inc. Adsorbent with multiple layers
EP2090361A1 (de) * 2008-02-14 2009-08-19 RESQ Lab B.V. Verbessertes Chromatographieharz sowie Verfahren und Vorrichtungen dafür
CN102549424B (zh) 2009-08-27 2016-01-13 全技术公司 合成真菌毒素吸附剂以及制备和使用所述合成真菌毒素吸附剂的方法
DE102015011884A1 (de) * 2015-09-10 2017-03-16 Sartorius Stedim Biotech Gmbh Adsorptionsmedium, Verfahren zu dessen Herstellung, sowie Verwendung desselben zur Aufreinigung von Biomolekülen
JP6737579B2 (ja) * 2015-10-30 2020-08-12 Jsr株式会社 アフィニティークロマトグラフィー用担体、クロマトグラフィーカラム、精製方法、及び該方法で精製された標的物質
EP4065619A1 (de) 2019-11-25 2022-10-05 3M Innovative Properties Company Biotin-enthaltende monomere und daraus hergestellte gegenstände
WO2023089538A1 (en) * 2021-11-19 2023-05-25 Waters Technologies Corporation A double surface modified porous material with minimized nonspecific interaction
TR2022014979A2 (tr) * 2022-09-30 2022-10-21 Bursa Uludag Ueniversitesi Kati faz ekstraksi̇yon kolonu

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029583A (en) * 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
US4478946A (en) * 1981-07-02 1984-10-23 South African Inventions Development Corporation Carrier bound immunosorbent
GB8516570D0 (en) * 1985-07-01 1985-08-07 Common Services Agency For The Coupling reaction
DE3782394T2 (de) * 1986-03-28 1993-05-19 Toray Industries Immobilisiertes, physiologisch aktives material.

Also Published As

Publication number Publication date
EP0295073A2 (de) 1988-12-14
EP0295073B1 (de) 1997-03-12
EP0295073A3 (de) 1990-12-19
JPH0769316B2 (ja) 1995-07-26
DE3855816T2 (de) 1997-11-27
DE3855816D1 (de) 1997-04-17
CA1320718C (en) 1993-07-27
JPS6472054A (en) 1989-03-16

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