ATE150305T1 - Therapeutische anwendung von histamin-h3- agonisten, neue wirkstoffe und verwendung zur herstellung von arzneimitteln - Google Patents

Therapeutische anwendung von histamin-h3- agonisten, neue wirkstoffe und verwendung zur herstellung von arzneimitteln

Info

Publication number: ATE150305T1
Authority: AT; Austria
Prior art keywords: histamine; agonists; active ingredients; new active; medicinal products
Prior art date: 1990-04-13

Application number

AT91400889T

Other languages

English (en)

Inventor

Jean Charles Schwartz

Monique Garbarg

Jean Michel Arrang

Charon Robin Ganellin

Jeanne Marie Lecomte

Original Assignee

Bioprojet Soc Civ

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-13

Filing date

1991-04-02

Publication date

1997-04-15

1991-04-02 Application filed by Bioprojet Soc Civ, Inst Nat Sante Rech Med filed Critical Bioprojet Soc Civ

1997-04-15 Application granted granted Critical

1997-04-15 Publication of ATE150305T1 publication Critical patent/ATE150305T1/de

Links

230000001225 therapeutic effect Effects 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 title 1
229940124806 histamine H3 agonist Drugs 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
239000003814 drug Substances 0.000 abstract 3
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical class NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229940121914 Histamine H3 receptor agonist Drugs 0.000 abstract 1
208000007107 Stomach Ulcer Diseases 0.000 abstract 1
230000001088 anti-asthma Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
239000000924 antiasthmatic agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
201000005917 gastric ulcer Diseases 0.000 abstract 1
239000003382 histamine H3 receptor agonist Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
239000000932 sedative agent Substances 0.000 abstract 1
230000001624 sedative effect Effects 0.000 abstract 1
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 1
229940125725 tranquilizer Drugs 0.000 abstract 1
239000003204 tranquilizing agent Substances 0.000 abstract 1
230000002936 tranquilizing effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Anesthesiology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT91400889T 1990-04-13 1991-04-02 Therapeutische anwendung von histamin-h3- agonisten, neue wirkstoffe und verwendung zur herstellung von arzneimitteln ATE150305T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9004861A FR2660862B1 (fr)	1990-04-13	1990-04-13	Application therapeutique de derives de l'histamine, nouveau derive de l'histamine et utilisation de ces derives pour la preparation de medicaments.

Publications (1)

Publication Number	Publication Date
ATE150305T1 true ATE150305T1 (de)	1997-04-15

Family

ID=9395796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91400889T ATE150305T1 (de)	1990-04-13	1991-04-02	Therapeutische anwendung von histamin-h3- agonisten, neue wirkstoffe und verwendung zur herstellung von arzneimitteln

Country Status (8)

Country	Link
EP (1)	EP0458661B1 (de)
JP (1)	JPH0532635A (de)
AT (1)	ATE150305T1 (de)
DE (1)	DE69125204T2 (de)
DK (1)	DK0458661T3 (de)
ES (1)	ES2099740T3 (de)
FR (1)	FR2660862B1 (de)
GR (1)	GR3023083T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5321039A (en) *	1990-04-13	1994-06-14	Societe Civile Bioprojet	Method of inducing a histamine agonist action on H2 receptors
US6407132B1 (en)	1997-07-25	2002-06-18	James Black Foundation Limited	Substituted imidazole derivatives and their use as histamine H3 receptor ligands
GB9715816D0 (en) *	1997-07-25	1997-10-01	Black James Foundation	Histamine H receptor ligands
JP2002534511A (ja)	1999-01-18	2002-10-15	ノボノルディスクアクティーゼルスカブ	置換型イミダゾール、それらの調製及び使用
US6908926B1 (en)	1999-04-16	2005-06-21	Novo Nordisk A/S	Substituted imidazoles, their preparation and use
US6437147B1 (en)	2000-03-17	2002-08-20	Novo Nordisk	Imidazole compounds
US6610721B2 (en)	2000-03-17	2003-08-26	Novo Nordisk A/S	Imidazo heterocyclic compounds
EP3378477A1 (de) *	2017-03-21	2018-09-26	BIOPROJET Pharma	Neue therapeutische verwendungen von h3-liganden

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3818097A (en) *	1969-10-29	1974-06-18	Smith Kline French Lab	Method of inhibiting histamine activity with isothioureas
BE758145A (fr) *	1969-10-29	1971-04-28	Smith Kline French Lab	Iso-thio-urees et derives
US3759944A (en) *	1970-10-14	1973-09-18	Smith Kline French Lab	Isothioureas and their derivatives
US3954982A (en) *	1972-04-20	1976-05-04	Smith Kline & French Laboratories Limited	Pharmaceutical compositions and method of inhibiting H-1 and H-2 histamine receptors
GB8916947D0 (en) *	1989-07-25	1989-09-13	Smith Kline French Lab	Medicaments

1990
- 1990-04-13 FR FR9004861A patent/FR2660862B1/fr not_active Expired - Fee Related
1991
- 1991-04-02 ES ES91400889T patent/ES2099740T3/es not_active Expired - Lifetime
- 1991-04-02 AT AT91400889T patent/ATE150305T1/de not_active IP Right Cessation
- 1991-04-02 DK DK91400889.1T patent/DK0458661T3/da active
- 1991-04-02 EP EP91400889A patent/EP0458661B1/de not_active Expired - Lifetime
- 1991-04-02 DE DE69125204T patent/DE69125204T2/de not_active Expired - Fee Related
- 1991-04-15 JP JP3109707A patent/JPH0532635A/ja active Pending
1997
- 1997-04-08 GR GR970400752T patent/GR3023083T3/el unknown

Also Published As

Publication number	Publication date
DE69125204D1 (de)	1997-04-24
FR2660862B1 (fr)	1994-09-23
JPH0532635A (ja)	1993-02-09
ES2099740T3 (es)	1997-06-01
EP0458661A1 (de)	1991-11-27
DE69125204T2 (de)	1997-06-26
FR2660862A1 (fr)	1991-10-18
EP0458661B1 (de)	1997-03-19
DK0458661T3 (da)	1997-07-28
GR3023083T3 (en)	1997-07-30

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Legal Events

Date	Code	Title	Description
1997-09-15	UEP	Publication of translation of european patent specification
2010-01-15	REN	Ceased due to non-payment of the annual fee