ATE150761T1 - 2-substituierte adenosine mit a-2 rezeptor affinität - Google Patents

2-substituierte adenosine mit a-2 rezeptor affinität

Info

Publication number: ATE150761T1
Authority: AT; Austria
Prior art keywords: adenosine; vitro; physiological effects; receptor affinity; receptor activity
Prior art date: 1992-09-30

Application number

AT93921304T

Other languages

English (en)

Inventor

Norton P Peet

David R Borcherding

Nelsen L Lentz

Philip M Weintraub

Original Assignee

Merrell Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-30

Filing date

1993-09-02

Publication date

1997-04-15

1993-09-02 Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc

1997-04-15 Application granted granted Critical

1997-04-15 Publication of ATE150761T1 publication Critical patent/ATE150761T1/de

Links

-1 2-SUBSTITUTED ADENOSINE Chemical class 0.000 title 1
102000009346 Adenosine receptors Human genes 0.000 abstract 3
108050000203 Adenosine receptors Proteins 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
230000003247 decreasing effect Effects 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
238000000338 in vitro Methods 0.000 abstract 2
230000001766 physiological effect Effects 0.000 abstract 2
150000003838 adenosines Chemical class 0.000 abstract 1
230000027455 binding Effects 0.000 abstract 1
230000036772 blood pressure Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000003379 purinergic P1 receptor agonist Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT93921304T 1992-09-30 1993-09-02 2-substituierte adenosine mit a-2 rezeptor affinität ATE150761T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US95418092A	1992-09-30	1992-09-30

Publications (1)

Publication Number	Publication Date
ATE150761T1 true ATE150761T1 (de)	1997-04-15

Family

ID=25495051

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93921304T ATE150761T1 (de)	1992-09-30	1993-09-02	2-substituierte adenosine mit a-2 rezeptor affinität

Country Status (19)

Country	Link
EP (1)	EP0662975B1 (de)
JP (1)	JPH08502069A (de)
KR (1)	KR100316354B1 (de)
AT (1)	ATE150761T1 (de)
AU (1)	AU672226B2 (de)
CA (1)	CA2145682C (de)
DE (1)	DE69309293T2 (de)
DK (1)	DK0662975T3 (de)
ES (1)	ES2102679T3 (de)
FI (1)	FI109129B (de)
GR (1)	GR3023761T3 (de)
HU (1)	HU220760B1 (de)
IL (2)	IL107101A0 (de)
MX (1)	MX9306032A (de)
NO (1)	NO303875B1 (de)
NZ (1)	NZ256195A (de)
TW (1)	TW302367B (de)
WO (1)	WO1994007905A1 (de)
ZA (1)	ZA937108B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6921753B2 (en)	2000-06-27	2005-07-26	Pfizer Inc	Purine derivatives
GB0015727D0 (en) *	2000-06-27	2000-08-16	Pfizer Ltd	Purine derivatives
GB0022695D0 (en)	2000-09-15	2000-11-01	Pfizer Ltd	Purine Derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5034381A (en) *	1988-01-07	1991-07-23	Ciba-Geigy Corporation	2-(substituted amino) adenosines as antihypertensives

1992
- 1992-09-24 IL IL107101A patent/IL107101A0/xx unknown
1993
- 1993-09-02 NZ NZ256195A patent/NZ256195A/en unknown
- 1993-09-02 EP EP93921304A patent/EP0662975B1/de not_active Expired - Lifetime
- 1993-09-02 DE DE69309293T patent/DE69309293T2/de not_active Expired - Fee Related
- 1993-09-02 AT AT93921304T patent/ATE150761T1/de not_active IP Right Cessation
- 1993-09-02 JP JP6509058A patent/JPH08502069A/ja active Pending
- 1993-09-02 DK DK93921304.7T patent/DK0662975T3/da active
- 1993-09-02 CA CA002145682A patent/CA2145682C/en not_active Expired - Fee Related
- 1993-09-02 HU HU9500918A patent/HU220760B1/hu not_active IP Right Cessation
- 1993-09-02 WO PCT/US1993/008269 patent/WO1994007905A1/en not_active Ceased
- 1993-09-02 KR KR1019950701220A patent/KR100316354B1/ko not_active Expired - Fee Related
- 1993-09-02 ES ES93921304T patent/ES2102679T3/es not_active Expired - Lifetime
- 1993-09-02 AU AU48446/93A patent/AU672226B2/en not_active Ceased
- 1993-09-24 ZA ZA937108A patent/ZA937108B/xx unknown
- 1993-09-24 IL IL10710193A patent/IL107101A/xx not_active IP Right Cessation
- 1993-09-25 TW TW082107911A patent/TW302367B/zh active
- 1993-09-29 MX MX9306032A patent/MX9306032A/es not_active IP Right Cessation
1995
- 1995-03-29 NO NO951213A patent/NO303875B1/no unknown
- 1995-03-29 FI FI951500A patent/FI109129B/fi active
1997
- 1997-06-11 GR GR970401405T patent/GR3023761T3/el unknown

Also Published As

Publication number	Publication date
DE69309293T2 (de)	1997-07-10
IL107101A (en)	2000-07-16
EP0662975A1 (de)	1995-07-19
DK0662975T3 (de)	1997-04-28
NO951213L (no)	1995-03-29
HU220760B1 (hu)	2002-05-28
KR100316354B1 (ko)	2002-09-26
FI951500L (fi)	1995-03-29
NZ256195A (en)	1996-05-28
JPH08502069A (ja)	1996-03-05
FI951500A0 (fi)	1995-03-29
EP0662975B1 (de)	1997-03-26
TW302367B (de)	1997-04-11
CA2145682C (en)	1998-11-10
IL107101A0 (en)	1993-12-28
FI109129B (fi)	2002-05-31
KR950703572A (ko)	1995-09-20
HU9500918D0 (en)	1995-05-29
GR3023761T3 (en)	1997-09-30
NO303875B1 (no)	1998-09-14
HUT72611A (en)	1996-05-28
CA2145682A1 (en)	1994-04-14
MX9306032A (es)	1994-03-31
NO951213D0 (no)	1995-03-29
WO1994007905A1 (en)	1994-04-14
AU4844693A (en)	1994-04-26
AU672226B2 (en)	1996-09-26
DE69309293D1 (de)	1997-04-30
ES2102679T3 (es)	1997-08-01
ZA937108B (en)	1994-05-17

Legal Events

Date	Code	Title	Description
1997-09-15	UEP	Publication of translation of european patent specification
2004-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3861517D1 (de)	1991-02-14	Blutdruckueberwacher.
WO2005000161A3 (en)	2005-10-20	Methods and devices for occluding body lumens and/or for delivering therapeutic agents
CA2013380A1 (en)	1990-09-29	Selective adenosine receptor agents
DK165982C (da)	1993-07-26	Imidazolylguanidinderivater og laegemidler, der indeholder disse forbindelser
DE69309293D1 (de)	1997-04-30	2-substituierte adenosine mit a-2 rezeptor affinität
ES2107431T3 (es)	1997-12-01	Agentes con accion selectiva sobre los receptores de la adenosina.
NO883047L (no)	1989-01-11	Substituerte benzimidazoler, fremgangsmaate til deres fremstilling, farmasoeytiske tilberedninger inneholdende dem ogderes anvendelse.
CA2013381A1 (en)	1990-09-29	Selective adenosine receptor compounds
EP0320207A3 (de)	1990-05-09	Methoden und Zusammensetzungen zur Aktivierung der menschlichen Insulinrezeptorkinase
DE69018554D1 (de)	1995-05-18	Pulsanzeigegerät.
FR2638523B1 (fr)	1991-02-01	Microcapteur de pression, notamment pour etudes medicales
CA2159989A1 (en)	1994-11-24	8-Substituted Xanthines as Selective Adenosine Receptor Agents
SE8702193D0 (sv)	1987-05-25	Insatspase engangs for blod, infusion och spolvetskor
IT8620110A0 (it)	1986-04-16	Sistema per la regolazione dell'atina dei cestelli estraibili dei mobili, mediante angolari filettati.
ITMI950956A0 (it)	1995-05-12	Uso degli enantiomeri (s) di derivati 1,4-diidropiridinici per il trattamento dell'insufficienza cardiaca
NO880051D0 (no)	1988-01-07	Tipp-beholder for kjoeretoey, fortrinnsvis skinnegaaende kjoeretoey.