NO303875B1 - 2-substituerte adenosiner med A-2-reseptoraffinitet - Google Patents

2-substituerte adenosiner med A-2-reseptoraffinitet

Info

Publication number: NO303875B1
Authority: NO; Norway
Prior art keywords: adenosine; vitro; physiological effects; receptor affinity; receptor activity
Prior art date: 1992-09-30

Application number

NO951213A

Other languages

English (en)

Norwegian (no)

Other versions

NO951213D0 (no

NO951213L (no

Inventor

Norton Paul Peet

David Roger Borcherding

Nelsen Lowell Lentz

Philip Marvin Weintraub

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-30

Filing date

1995-03-29

Publication date

1998-09-14

1995-03-29 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1995-03-29 Publication of NO951213D0 publication Critical patent/NO951213D0/no

1995-03-29 Publication of NO951213L publication Critical patent/NO951213L/no

1998-09-14 Publication of NO303875B1 publication Critical patent/NO303875B1/no

Links

-1 2-substituted adenosines Chemical class 0.000 title 1
102000009346 Adenosine receptors Human genes 0.000 abstract 3
108050000203 Adenosine receptors Proteins 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
230000003247 decreasing effect Effects 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
238000000338 in vitro Methods 0.000 abstract 2
230000001766 physiological effect Effects 0.000 abstract 2
150000003838 adenosines Chemical class 0.000 abstract 1
230000027455 binding Effects 0.000 abstract 1
230000036772 blood pressure Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000003379 purinergic P1 receptor agonist Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

NO951213A 1992-09-30 1995-03-29 2-substituerte adenosiner med A-2-reseptoraffinitet NO303875B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US95418092A	1992-09-30	1992-09-30
PCT/US1993/008269 WO1994007905A1 (en)	1992-09-30	1993-09-02	2-substituted adenosines with a-2 receptor affinity

Publications (3)

Publication Number	Publication Date
NO951213D0 NO951213D0 (no)	1995-03-29
NO951213L NO951213L (no)	1995-03-29
NO303875B1 true NO303875B1 (no)	1998-09-14

Family

ID=25495051

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO951213A NO303875B1 (no)	1992-09-30	1995-03-29	2-substituerte adenosiner med A-2-reseptoraffinitet

Country Status (19)

Country	Link
EP (1)	EP0662975B1 (de)
JP (1)	JPH08502069A (de)
KR (1)	KR100316354B1 (de)
AT (1)	ATE150761T1 (de)
AU (1)	AU672226B2 (de)
CA (1)	CA2145682C (de)
DE (1)	DE69309293T2 (de)
DK (1)	DK0662975T3 (de)
ES (1)	ES2102679T3 (de)
FI (1)	FI109129B (de)
GR (1)	GR3023761T3 (de)
HU (1)	HU220760B1 (de)
IL (2)	IL107101A0 (de)
MX (1)	MX9306032A (de)
NO (1)	NO303875B1 (de)
NZ (1)	NZ256195A (de)
TW (1)	TW302367B (de)
WO (1)	WO1994007905A1 (de)
ZA (1)	ZA937108B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0015727D0 (en) *	2000-06-27	2000-08-16	Pfizer Ltd	Purine derivatives
US6921753B2 (en)	2000-06-27	2005-07-26	Pfizer Inc	Purine derivatives
GB0022695D0 (en)	2000-09-15	2000-11-01	Pfizer Ltd	Purine Derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5034381A (en) *	1988-01-07	1991-07-23	Ciba-Geigy Corporation	2-(substituted amino) adenosines as antihypertensives

1992
- 1992-09-24 IL IL107101A patent/IL107101A0/xx unknown
1993
- 1993-09-02 NZ NZ256195A patent/NZ256195A/en unknown
- 1993-09-02 JP JP6509058A patent/JPH08502069A/ja active Pending
- 1993-09-02 AT AT93921304T patent/ATE150761T1/de not_active IP Right Cessation
- 1993-09-02 ES ES93921304T patent/ES2102679T3/es not_active Expired - Lifetime
- 1993-09-02 DK DK93921304.7T patent/DK0662975T3/da active
- 1993-09-02 AU AU48446/93A patent/AU672226B2/en not_active Ceased
- 1993-09-02 DE DE69309293T patent/DE69309293T2/de not_active Expired - Fee Related
- 1993-09-02 HU HU9500918A patent/HU220760B1/hu not_active IP Right Cessation
- 1993-09-02 KR KR1019950701220A patent/KR100316354B1/ko not_active Expired - Fee Related
- 1993-09-02 CA CA002145682A patent/CA2145682C/en not_active Expired - Fee Related
- 1993-09-02 EP EP93921304A patent/EP0662975B1/de not_active Expired - Lifetime
- 1993-09-02 WO PCT/US1993/008269 patent/WO1994007905A1/en not_active Ceased
- 1993-09-24 IL IL10710193A patent/IL107101A/xx not_active IP Right Cessation
- 1993-09-24 ZA ZA937108A patent/ZA937108B/xx unknown
- 1993-09-25 TW TW082107911A patent/TW302367B/zh active
- 1993-09-29 MX MX9306032A patent/MX9306032A/es not_active IP Right Cessation
1995
- 1995-03-29 NO NO951213A patent/NO303875B1/no unknown
- 1995-03-29 FI FI951500A patent/FI109129B/fi active
1997
- 1997-06-11 GR GR970401405T patent/GR3023761T3/el unknown

Also Published As

Publication number	Publication date
NO951213D0 (no)	1995-03-29
FI951500A0 (fi)	1995-03-29
EP0662975B1 (de)	1997-03-26
DE69309293T2 (de)	1997-07-10
WO1994007905A1 (en)	1994-04-14
CA2145682A1 (en)	1994-04-14
HU220760B1 (hu)	2002-05-28
AU4844693A (en)	1994-04-26
JPH08502069A (ja)	1996-03-05
NO951213L (no)	1995-03-29
TW302367B (de)	1997-04-11
ATE150761T1 (de)	1997-04-15
KR100316354B1 (ko)	2002-09-26
DE69309293D1 (de)	1997-04-30
FI109129B (fi)	2002-05-31
MX9306032A (es)	1994-03-31
GR3023761T3 (en)	1997-09-30
IL107101A (en)	2000-07-16
HU9500918D0 (en)	1995-05-29
NZ256195A (en)	1996-05-28
FI951500L (fi)	1995-03-29
DK0662975T3 (de)	1997-04-28
ES2102679T3 (es)	1997-08-01
HUT72611A (en)	1996-05-28
KR950703572A (ko)	1995-09-20
AU672226B2 (en)	1996-09-26
CA2145682C (en)	1998-11-10
ZA937108B (en)	1994-05-17
IL107101A0 (en)	1993-12-28
EP0662975A1 (de)	1995-07-19

Publication	Publication Date	Title
WO2005000161A3 (en)	2005-10-20	Methods and devices for occluding body lumens and/or for delivering therapeutic agents
CA2013380A1 (en)	1990-09-29	Selective adenosine receptor agents
TR200001892T2 (tr)	2000-11-21	Monomer cinsi ensülin analogları ve bunların kullanımı.
KR950700333A (ko)	1995-01-16	개량된 알파 인터페론 조성물 및 인간 말초혈 백혈구로부터의 제조 방법(improved alpha interferon composition and method for its production from human peripheral blood leukocytes)
DE69626705D1 (de)	2003-04-17	A1 adenosin rezeptor agonisten und antagonisten
DE3850869D1 (de)	1994-09-01	Blutdruck-Messgerät.
FI951500A0 (fi)	1995-03-29	2-substituoituja adenosiineja, joilla on A-2-reseptoriaffiniteetti
CA2038747A1 (en)	1991-09-27	Selective adenosine receptor agents
DK0686155T3 (da)	1999-02-01	Xanthinderivater som adenosin A1-receptor-antagonister
Rustum et al.	1987	Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C
CA2013381A1 (en)	1990-09-29	Selective adenosine receptor compounds
CA2159989A1 (en)	1994-11-24	8-Substituted Xanthines as Selective Adenosine Receptor Agents
ATE153027T1 (de)	1997-05-15	Zuckerderivate von makroliden
SE8702193D0 (sv)	1987-05-25	Insatspase engangs for blod, infusion och spolvetskor
ES1001778U (es)	1988-05-16	Abrazadera perfeccionada
DK38288D0 (da)	1988-01-27	Sparsomycin (sc-rs) sammensaetninger med antitumoraktivitet, fremgangsmaade til fremstilling deraf og farmaceutiske sammensaetninger indeholdende sparsomycin (sc-rs) sammensaetninger