ATE150767T1 - Kleine zyklische inhibitoren der blutplättchenaggregation - Google Patents

Kleine zyklische inhibitoren der blutplättchenaggregation

Info

Publication number
ATE150767T1
ATE150767T1 AT90911371T AT90911371T ATE150767T1 AT E150767 T1 ATE150767 T1 AT E150767T1 AT 90911371 T AT90911371 T AT 90911371T AT 90911371 T AT90911371 T AT 90911371T AT E150767 T1 ATE150767 T1 AT E150767T1
Authority
AT
Austria
Prior art keywords
platele
aggregation inhibitors
small cyclic
cyclic
inhibitors
Prior art date
Application number
AT90911371T
Other languages
English (en)
Inventor
Peter L Barker
John P Burnier
Thomas Gadek
Eugene D Thorsett
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE150767T1 publication Critical patent/ATE150767T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/065—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for hydroxy functions, not being part of carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90911371T 1989-07-17 1990-07-05 Kleine zyklische inhibitoren der blutplättchenaggregation ATE150767T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/380,957 US5384309A (en) 1989-07-17 1989-07-17 Cyclized peptides and their use as platelet aggregation inhibitors

Publications (1)

Publication Number Publication Date
ATE150767T1 true ATE150767T1 (de) 1997-04-15

Family

ID=23503097

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90911371T ATE150767T1 (de) 1989-07-17 1990-07-05 Kleine zyklische inhibitoren der blutplättchenaggregation

Country Status (8)

Country Link
US (1) US5384309A (de)
EP (1) EP0482080B1 (de)
JP (1) JPH04506803A (de)
AT (1) ATE150767T1 (de)
AU (1) AU6049690A (de)
CA (1) CA2063557A1 (de)
DE (1) DE69030315T2 (de)
WO (1) WO1991001331A1 (de)

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TW201806968A (zh) 2011-10-18 2018-03-01 艾利倫治療公司 擬肽巨環化合物
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JP2018503595A (ja) * 2014-09-24 2018-02-08 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその製剤
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US10023613B2 (en) 2015-09-10 2018-07-17 Aileron Therapeutics, Inc. Peptidomimetic macrocycles as modulators of MCL-1
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JP7670618B2 (ja) 2019-03-14 2025-04-30 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 環状ペプチド抗生物質
WO2021113514A1 (en) * 2019-12-05 2021-06-10 Fresenius Kabi Usa, Llc Method for analyzing degarelix and associated products
CN111454329A (zh) * 2020-04-07 2020-07-28 哈尔滨师范大学 一种具有抗癌活性的异茚哚酮桥连环九肽及其制备方法

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Also Published As

Publication number Publication date
US5384309A (en) 1995-01-24
AU6049690A (en) 1991-02-22
DE69030315T2 (de) 1997-09-11
EP0482080B1 (de) 1997-03-26
CA2063557A1 (en) 1991-01-18
EP0482080A1 (de) 1992-04-29
JPH04506803A (ja) 1992-11-26
DE69030315D1 (de) 1997-04-30
WO1991001331A1 (en) 1991-02-07

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Legal Events

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time