ATE152720T1 - Zyklische (hetero)acetale nitrosubstituierter benzaldehyde mit wirkung gegen krebs - Google Patents

Zyklische (hetero)acetale nitrosubstituierter benzaldehyde mit wirkung gegen krebs

Info

Publication number
ATE152720T1
ATE152720T1 AT91310790T AT91310790T ATE152720T1 AT E152720 T1 ATE152720 T1 AT E152720T1 AT 91310790 T AT91310790 T AT 91310790T AT 91310790 T AT91310790 T AT 91310790T AT E152720 T1 ATE152720 T1 AT E152720T1
Authority
AT
Austria
Prior art keywords
cyclic
nitrosubstituted
benzaldehydes
acetals
hetero
Prior art date
Application number
AT91310790T
Other languages
English (en)
Inventor
Erik Olai Petterson
Rolf Olav Larsen
Bernt Borretzen
John Michael Dornish
Reidar Oftebro
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Application granted granted Critical
Publication of ATE152720T1 publication Critical patent/ATE152720T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT91310790T 1990-11-30 1991-11-22 Zyklische (hetero)acetale nitrosubstituierter benzaldehyde mit wirkung gegen krebs ATE152720T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026114A GB9026114D0 (en) 1990-11-30 1990-11-30 New compounds

Publications (1)

Publication Number Publication Date
ATE152720T1 true ATE152720T1 (de) 1997-05-15

Family

ID=10686289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91310790T ATE152720T1 (de) 1990-11-30 1991-11-22 Zyklische (hetero)acetale nitrosubstituierter benzaldehyde mit wirkung gegen krebs

Country Status (11)

Country Link
US (1) US5393741A (de)
EP (1) EP0493883B1 (de)
JP (1) JPH054985A (de)
AT (1) ATE152720T1 (de)
AU (1) AU635445B2 (de)
CA (1) CA2056693A1 (de)
DE (1) DE69126009T2 (de)
DK (1) DK0493883T3 (de)
ES (1) ES2103785T3 (de)
GB (1) GB9026114D0 (de)
GR (1) GR3023755T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9201275D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
GB9201274D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
CN1056082C (zh) * 1994-04-08 2000-09-06 北京市兴大科学系统公司 一种抗癌药
JP2990015B2 (ja) * 1994-06-20 1999-12-13 睦之 東風 抗ｈｉｖ剤
US6777217B1 (en) 1996-03-26 2004-08-17 President And Fellows Of Harvard College Histone deacetylases, and uses related thereto
US20030129724A1 (en) 2000-03-03 2003-07-10 Grozinger Christina M. Class II human histone deacetylases, and uses related thereto
WO2002089782A2 (en) * 2001-05-09 2002-11-14 President And Fellows Of Harvard College Dioxanes and uses thereof
US7244853B2 (en) * 2001-05-09 2007-07-17 President And Fellows Of Harvard College Dioxanes and uses thereof
US8999289B2 (en) 2005-03-22 2015-04-07 President And Fellows Of Harvard College Treatment of protein degradation disorders
WO2007095584A2 (en) 2006-02-14 2007-08-23 The President And Fellows Of Harvard College Histone Deacetylase Inhibitors
US8222423B2 (en) 2006-02-14 2012-07-17 Dana-Farber Cancer Institute, Inc. Bifunctional histone deacetylase inhibitors
US8304451B2 (en) * 2006-05-03 2012-11-06 President And Fellows Of Harvard College Histone deacetylase and tubulin deacetylase inhibitors
AU2009274549B2 (en) * 2008-07-23 2014-05-01 Dana-Farber Cancer Institute, Inc. Deacetylase inhibitors and uses thereof
WO2011019393A2 (en) 2009-08-11 2011-02-17 President And Fellows Of Harvard College Class- and isoform-specific hdac inhibitors and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1289966A (de) * 1968-12-24 1972-09-20
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
JPS5788170A (en) * 1980-11-18 1982-06-01 Hisamitsu Pharmaceut Co Inc Thiazolidone derivative
US4552888A (en) * 1982-01-15 1985-11-12 Eli Lilly And Company Ascorbic acid ethers in angiogene
FI830078L (fi) * 1982-01-15 1983-07-16 Lilly Co Eli Askorbinsyraetrar och liknande foereningar
EP0085760A3 (de) * 1982-02-04 1984-07-04 American Cyanamid Company 1,4-bis(substituiertes Amino)-5,8-Dihydroxy Anthraquinon und die entsprechenden Leucobasen
JPS60139619A (ja) * 1983-12-27 1985-07-24 Mutsuyuki Kochi Ｏ−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
US4723986A (en) * 1986-05-19 1988-02-09 Stauffer Chemical Company Herbicidal oxazolidines and methods of use
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
US5149820A (en) * 1987-03-11 1992-09-22 Norsk Hydro A.S. Deuterated compounds
GB8810173D0 (en) * 1988-04-29 1988-06-02 Norsk Hydro As Pharmaceutical compositions with anti-cancer activity & method for treatment of cancer
US5032610A (en) * 1988-11-21 1991-07-16 Norsk Hydro As Activity against carcinoma and method for the treatment of carcinoma
US5135948A (en) * 1988-11-21 1992-08-04 Norsk Hydro A.S. Pharmaceutical compositions with anti-cancer activity against carcinoma and method for the treatment of carcinoma

Also Published As

Publication number Publication date
US5393741A (en) 1995-02-28
DE69126009D1 (de) 1997-06-12
ES2103785T3 (es) 1997-10-01
EP0493883A1 (de) 1992-07-08
EP0493883B1 (de) 1997-05-07
GB9026114D0 (en) 1991-01-16
AU635445B2 (en) 1993-03-18
CA2056693A1 (en) 1992-05-31
AU8813891A (en) 1992-06-04
DE69126009T2 (de) 1997-09-18
GR3023755T3 (en) 1997-09-30
DK0493883T3 (da) 1997-10-13
JPH054985A (ja) 1993-01-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee