ATE153344T1 - Hemmung von mineralabsetzung mit hilfe von phosphorylierten und ähnlichen polyanionischen peptiden - Google Patents

Hemmung von mineralabsetzung mit hilfe von phosphorylierten und ähnlichen polyanionischen peptiden

Info

Publication number: ATE153344T1
Authority: AT; Austria
Prior art keywords: phosphorylated; inhibition; similar; mineral deposition; peptides
Prior art date: 1989-04-07

Application number

AT90303465T

Other languages

English (en)

Inventor

Charles Steven Sikes

Original Assignee

Univ South Alabama

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-07

Filing date

1990-03-30

Publication date

1997-06-15

1989-04-07 Priority claimed from US07/334,456 external-priority patent/US5051401A/en

1990-03-30 Application filed by Univ South Alabama filed Critical Univ South Alabama

1997-06-15 Application granted granted Critical

1997-06-15 Publication of ATE153344T1 publication Critical patent/ATE153344T1/de

Links

230000008021 deposition Effects 0.000 title abstract 2
229910052500 inorganic mineral Inorganic materials 0.000 title abstract 2
239000011707 mineral Substances 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
230000005764 inhibitory process Effects 0.000 title 1
229940024606 amino acid Drugs 0.000 abstract 3
BZQFBWGGLXLEPQ-UHFFFAOYSA-N O-phosphoryl-L-serine Natural products OC(=O)C(N)COP(O)(O)=O BZQFBWGGLXLEPQ-UHFFFAOYSA-N 0.000 abstract 2
235000001014 amino acid Nutrition 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
229950006137 dexfosfoserine Drugs 0.000 abstract 2
BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 abstract 2
BEWZOYANBGCCRH-VKHMYHEASA-N (2s)-5-amino-5-oxo-2-(phosphonoamino)pentanoic acid Chemical compound NC(=O)CC[C@@H](C(O)=O)NP(O)(O)=O BEWZOYANBGCCRH-VKHMYHEASA-N 0.000 abstract 1
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract 1
FXDNYOANAXWZHG-VKHMYHEASA-N O-phospho-L-homoserine Chemical compound OC(=O)[C@@H](N)CCOP(O)(O)=O FXDNYOANAXWZHG-VKHMYHEASA-N 0.000 abstract 1
FXDNYOANAXWZHG-UHFFFAOYSA-N O-phospho-L-homoserine Natural products OC(=O)C(N)CCOP(O)(O)=O FXDNYOANAXWZHG-UHFFFAOYSA-N 0.000 abstract 1
125000000129 anionic group Chemical group 0.000 abstract 1
229960001230 asparagine Drugs 0.000 abstract 1
235000009582 asparagine Nutrition 0.000 abstract 1
229940009098 aspartate Drugs 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-L aspartate group Chemical group N[C@@H](CC(=O)[O-])C(=O)[O-] CKLJMWTZIZZHCS-REOHCLBHSA-L 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
229940049906 glutamate Drugs 0.000 abstract 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
229960002743 glutamine Drugs 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
LGZSREIUDDFVJE-REOHCLBHSA-N phospho-asparagine Chemical compound NC(=O)C[C@@H](C(O)=O)NP(O)(O)=O LGZSREIUDDFVJE-REOHCLBHSA-N 0.000 abstract 1
USRGIUJOYOXOQJ-GBXIJSLDSA-N phosphothreonine Chemical compound OP(=O)(O)O[C@H](C)[C@H](N)C(O)=O USRGIUJOYOXOQJ-GBXIJSLDSA-N 0.000 abstract 1
DCWXELXMIBXGTH-UHFFFAOYSA-N phosphotyrosine Chemical compound OC(=O)C(N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-UHFFFAOYSA-N 0.000 abstract 1
-1 poly-amino acid compound Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Oral & Maxillofacial Surgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Birds (AREA)
Peptides Or Proteins (AREA)
Polyamides (AREA)
Cosmetics (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90303465T 1989-04-07 1990-03-30 Hemmung von mineralabsetzung mit hilfe von phosphorylierten und ähnlichen polyanionischen peptiden ATE153344T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/334,456 US5051401A (en)	1989-04-07	1989-04-07	Inhibition of mineral deposition by phosphorylated and related polyanionic peptides
US33967289A	1989-04-18	1989-04-18

Publications (1)

Publication Number	Publication Date
ATE153344T1 true ATE153344T1 (de)	1997-06-15

Family

ID=26989201

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90303465T ATE153344T1 (de)	1989-04-07	1990-03-30	Hemmung von mineralabsetzung mit hilfe von phosphorylierten und ähnlichen polyanionischen peptiden

Country Status (8)

Country	Link
EP (1)	EP0391629B1 (de)
JP (1)	JP2716241B2 (de)
AT (1)	ATE153344T1 (de)
CA (1)	CA2014051A1 (de)
DE (1)	DE69030747T2 (de)
DK (1)	DK0391629T3 (de)
ES (1)	ES2103725T3 (de)
GR (1)	GR3024363T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0523776A3 (en) *	1991-07-17	1993-05-26	Unilever N.V.	Oral compositions containing a phosphopeptide
US5227154A (en) *	1991-08-22	1993-07-13	The University Of Melbourne	Phosphopeptides for the treatment of dental calculus
DE4217847A1 (de) *	1992-05-29	1993-12-02	Basf Ag	Verwendung von Kondensaten der Asparaginsäure als Belagsverhinderer bei der Eindampfung von Zuckersäften
US5286480A (en) *	1992-06-29	1994-02-15	The Procter & Gamble Company	Use of N-acetylated amino acid complexes in oral care compositions
US5500208A (en) *	1994-06-07	1996-03-19	The Procter & Gamble Company	Oral compositions comprising a novel tripeptide
US6004390A (en)	1997-04-14	1999-12-21	Dentsply Detrey Gmbh	Tooth surface treatment composition and methods
KR20030095501A (ko) *	2002-06-12	2003-12-24	김운중	이산화티탄이 함유된 조화(造花) 및 그 제조방법
WO2009075788A1 (en) *	2007-12-05	2009-06-18	Semprus Biociences Corporation	Synthetic non-fouling amino acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60156620A (ja) *	1983-12-22	1985-08-16	ザ　ユニヴアーシテイ　オブ　メルボルン	齲歯抑制剤
CA1315480C (en) *	1986-06-12	1993-03-30	Eric Charles Reynolds	Phosphopeptides

1990
- 1990-03-30 DK DK90303465.0T patent/DK0391629T3/da active
- 1990-03-30 AT AT90303465T patent/ATE153344T1/de not_active IP Right Cessation
- 1990-03-30 ES ES90303465T patent/ES2103725T3/es not_active Expired - Lifetime
- 1990-03-30 EP EP90303465A patent/EP0391629B1/de not_active Expired - Lifetime
- 1990-03-30 DE DE69030747T patent/DE69030747T2/de not_active Expired - Fee Related
- 1990-04-06 JP JP2091944A patent/JP2716241B2/ja not_active Expired - Lifetime
- 1990-04-06 CA CA002014051A patent/CA2014051A1/en not_active Abandoned
1997
- 1997-08-06 GR GR970402010T patent/GR3024363T3/el unknown

Also Published As

Publication number	Publication date
CA2014051A1 (en)	1990-10-07
EP0391629B1 (de)	1997-05-21
DK0391629T3 (da)	1997-12-15
EP0391629A1 (de)	1990-10-10
JP2716241B2 (ja)	1998-02-18
GR3024363T3 (en)	1997-11-28
JPH0368598A (ja)	1991-03-25
DE69030747T2 (de)	1998-01-22
ES2103725T3 (es)	1997-10-01
DE69030747D1 (de)	1997-06-26

Legal Events

Date	Code	Title	Description
1998-01-15	UEP	Publication of translation of european patent specification
2002-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3751652D1 (en)	1996-02-08	Phosphopeptide
CA2106400A1 (en)	1992-08-22	Polyamino acid dispersants
IL96434A0 (en)	1991-08-16	Cascade polymers,processes for the preparation thereof and pharmaceutical compositions containing the same
AU3049895A (en)	1996-04-04	Method of inhibiting sulfate scale in aqueous systems
CA2011294A1 (en)	1990-09-03	Carbonylation catalyst system
AU4015593A (en)	1994-01-13	Method for preparing polysuccinimides using a rotary tray dryer
AU5701990A (en)	1990-12-13	4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof, compositions and uses therefor and processes of preparation.
DE69030747D1 (de)	1997-06-26	Hemmung von Mineralabsetzung mit Hilfe von phosphorylierten und ähnlichen polyanionischen Peptiden
DE59407852D1 (de)	1999-04-01	Zusammensetzung zur aufbereitung von wasser und sanierung von böden
PH30410A (en)	1997-05-09	A process for inhibiting growth or proliferation of tumor
EP0209848A3 (de)	1988-07-27	Enzyminhibitoren
AU588192B2 (en)	1989-09-07	Amino phosphonic acid/phosphate mixtures for controlling corrosion of metal and inhibiting calcium phosphate precipitation
FR2693473B1 (fr)	1994-09-09	Procédé de préparation enzymatique d'hydrolysats de matières protéiques.
ATE76857T1 (de)	1992-06-15	Verfahren zum kontrollieren von kalziumoxalatablagerungen in einem ausgedehnten ph-bereich.
EP0316725A3 (de)	1991-01-23	Verfahren zur enzymatischen Peptidsynthese mit mindestens einer nicht-proteinogenen Aminsäure sowie die neuen, bei der Synthese anfallenden Peptide
CA2171953A1 (en)	1995-03-30	Modified truncated complement system regulators
AU639751B2 (en)	1993-08-05	Temporary minimal protection synthesis of lh-rh analogs
SG47712A1 (en)	1998-04-17	Process for the preparation of 2,4,5-tribromopyrrole-3-carbonitrile
EP0679659A4 (de)	1996-05-22	Inhibitor peptid spezifisch für cathepsin-l.
EP0294126A3 (de)	1990-08-01	Mischung auf der Basis halogenhaltiger Harze
CA2029073A1 (en)	1991-10-21	Scale control in aqueous systems
TH19899A (de)	1996-08-07
RU93014632A (ru)	1996-07-20	Комплексная добавка для гипсовой смеси
JPS5665852A (en)	1981-06-03	Production of carboxylic acid amide