DK0391629T3 - Inhibering af mineralaflejring ved hjælp af phosphorylerede og beslægtede polyanioniske peptider - Google Patents
Inhibering af mineralaflejring ved hjælp af phosphorylerede og beslægtede polyanioniske peptiderInfo
- Publication number
- DK0391629T3 DK0391629T3 DK90303465.0T DK90303465T DK0391629T3 DK 0391629 T3 DK0391629 T3 DK 0391629T3 DK 90303465 T DK90303465 T DK 90303465T DK 0391629 T3 DK0391629 T3 DK 0391629T3
- Authority
- DK
- Denmark
- Prior art keywords
- phosphorylated
- inhibition
- mineral deposition
- peptides
- polyanionic peptides
- Prior art date
Links
- 230000008021 deposition Effects 0.000 title abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 title abstract 2
- 239000011707 mineral Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- 229940024606 amino acid Drugs 0.000 abstract 3
- BZQFBWGGLXLEPQ-UHFFFAOYSA-N O-phosphoryl-L-serine Natural products OC(=O)C(N)COP(O)(O)=O BZQFBWGGLXLEPQ-UHFFFAOYSA-N 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229950006137 dexfosfoserine Drugs 0.000 abstract 2
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 abstract 2
- BEWZOYANBGCCRH-VKHMYHEASA-N (2s)-5-amino-5-oxo-2-(phosphonoamino)pentanoic acid Chemical compound NC(=O)CC[C@@H](C(O)=O)NP(O)(O)=O BEWZOYANBGCCRH-VKHMYHEASA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract 1
- FXDNYOANAXWZHG-VKHMYHEASA-N O-phospho-L-homoserine Chemical compound OC(=O)[C@@H](N)CCOP(O)(O)=O FXDNYOANAXWZHG-VKHMYHEASA-N 0.000 abstract 1
- FXDNYOANAXWZHG-UHFFFAOYSA-N O-phospho-L-homoserine Natural products OC(=O)C(N)CCOP(O)(O)=O FXDNYOANAXWZHG-UHFFFAOYSA-N 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 229940009098 aspartate Drugs 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-L aspartate group Chemical group N[C@@H](CC(=O)[O-])C(=O)[O-] CKLJMWTZIZZHCS-REOHCLBHSA-L 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 229940049906 glutamate Drugs 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 229960002743 glutamine Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LGZSREIUDDFVJE-REOHCLBHSA-N phospho-asparagine Chemical compound NC(=O)C[C@@H](C(O)=O)NP(O)(O)=O LGZSREIUDDFVJE-REOHCLBHSA-N 0.000 abstract 1
- USRGIUJOYOXOQJ-GBXIJSLDSA-N phosphothreonine Chemical compound OP(=O)(O)O[C@H](C)[C@H](N)C(O)=O USRGIUJOYOXOQJ-GBXIJSLDSA-N 0.000 abstract 1
- DCWXELXMIBXGTH-UHFFFAOYSA-N phosphotyrosine Chemical compound OC(=O)C(N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-UHFFFAOYSA-N 0.000 abstract 1
- -1 poly-amino acid compound Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Birds (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/334,456 US5051401A (en) | 1989-04-07 | 1989-04-07 | Inhibition of mineral deposition by phosphorylated and related polyanionic peptides |
| US33967289A | 1989-04-18 | 1989-04-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0391629T3 true DK0391629T3 (da) | 1997-12-15 |
Family
ID=26989201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90303465.0T DK0391629T3 (da) | 1989-04-07 | 1990-03-30 | Inhibering af mineralaflejring ved hjælp af phosphorylerede og beslægtede polyanioniske peptider |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0391629B1 (da) |
| JP (1) | JP2716241B2 (da) |
| AT (1) | ATE153344T1 (da) |
| CA (1) | CA2014051A1 (da) |
| DE (1) | DE69030747T2 (da) |
| DK (1) | DK0391629T3 (da) |
| ES (1) | ES2103725T3 (da) |
| GR (1) | GR3024363T3 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0523776A3 (en) * | 1991-07-17 | 1993-05-26 | Unilever N.V. | Oral compositions containing a phosphopeptide |
| US5227154A (en) * | 1991-08-22 | 1993-07-13 | The University Of Melbourne | Phosphopeptides for the treatment of dental calculus |
| DE4217847A1 (de) * | 1992-05-29 | 1993-12-02 | Basf Ag | Verwendung von Kondensaten der Asparaginsäure als Belagsverhinderer bei der Eindampfung von Zuckersäften |
| US5286480A (en) * | 1992-06-29 | 1994-02-15 | The Procter & Gamble Company | Use of N-acetylated amino acid complexes in oral care compositions |
| US5500208A (en) * | 1994-06-07 | 1996-03-19 | The Procter & Gamble Company | Oral compositions comprising a novel tripeptide |
| US6004390A (en) | 1997-04-14 | 1999-12-21 | Dentsply Detrey Gmbh | Tooth surface treatment composition and methods |
| KR20030095501A (ko) * | 2002-06-12 | 2003-12-24 | 김운중 | 이산화티탄이 함유된 조화(造花) 및 그 제조방법 |
| US20090149673A1 (en) * | 2007-12-05 | 2009-06-11 | Semprus Biosciences Corp. | Synthetic non-fouling amino acids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE73668T1 (de) * | 1983-12-22 | 1992-04-15 | Univ Melbourne | Karieshemmung. |
| CA1315480C (en) * | 1986-06-12 | 1993-03-30 | Eric Charles Reynolds | Phosphopeptides |
-
1990
- 1990-03-30 AT AT90303465T patent/ATE153344T1/de not_active IP Right Cessation
- 1990-03-30 DK DK90303465.0T patent/DK0391629T3/da active
- 1990-03-30 EP EP90303465A patent/EP0391629B1/en not_active Expired - Lifetime
- 1990-03-30 ES ES90303465T patent/ES2103725T3/es not_active Expired - Lifetime
- 1990-03-30 DE DE69030747T patent/DE69030747T2/de not_active Expired - Fee Related
- 1990-04-06 JP JP2091944A patent/JP2716241B2/ja not_active Expired - Lifetime
- 1990-04-06 CA CA002014051A patent/CA2014051A1/en not_active Abandoned
-
1997
- 1997-08-06 GR GR970402010T patent/GR3024363T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE153344T1 (de) | 1997-06-15 |
| ES2103725T3 (es) | 1997-10-01 |
| DE69030747D1 (de) | 1997-06-26 |
| EP0391629A1 (en) | 1990-10-10 |
| EP0391629B1 (en) | 1997-05-21 |
| GR3024363T3 (en) | 1997-11-28 |
| DE69030747T2 (de) | 1998-01-22 |
| JPH0368598A (ja) | 1991-03-25 |
| JP2716241B2 (ja) | 1998-02-18 |
| CA2014051A1 (en) | 1990-10-07 |
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