ATE153383T1 - Rekombinante dna-methode und vektoren, die dafür benutzt werden - Google Patents
Rekombinante dna-methode und vektoren, die dafür benutzt werdenInfo
- Publication number
- ATE153383T1 ATE153383T1 AT90916069T AT90916069T ATE153383T1 AT E153383 T1 ATE153383 T1 AT E153383T1 AT 90916069 T AT90916069 T AT 90916069T AT 90916069 T AT90916069 T AT 90916069T AT E153383 T1 ATE153383 T1 AT E153383T1
- Authority
- AT
- Austria
- Prior art keywords
- gene
- glutamine
- recombinant dna
- vectors used
- dna method
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 101150074355 GS gene Proteins 0.000 abstract 6
- 210000004027 cell Anatomy 0.000 abstract 3
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 3
- 238000012258 culturing Methods 0.000 abstract 2
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898924021A GB8924021D0 (en) | 1989-10-25 | 1989-10-25 | Recombinant dna method and vectors for the use therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE153383T1 true ATE153383T1 (de) | 1997-06-15 |
Family
ID=10665141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90916069T ATE153383T1 (de) | 1989-10-25 | 1990-10-25 | Rekombinante dna-methode und vektoren, die dafür benutzt werden |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0491875B1 (de) |
| JP (1) | JP3073009B2 (de) |
| AT (1) | ATE153383T1 (de) |
| AU (1) | AU6629990A (de) |
| CA (1) | CA2071543C (de) |
| DE (1) | DE69030768T2 (de) |
| DK (1) | DK0491875T3 (de) |
| ES (1) | ES2104616T3 (de) |
| GB (1) | GB8924021D0 (de) |
| GR (1) | GR3023510T3 (de) |
| WO (1) | WO1991006657A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| CA2257357C (en) | 1996-06-07 | 2010-04-13 | Neorx Corporation | Humanized antibodies with modified glycosylation |
| EP2213743A1 (de) | 2000-04-12 | 2010-08-04 | Human Genome Sciences, Inc. | Albuminfusionsproteine |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| EP2431054A3 (de) | 2000-06-15 | 2013-03-06 | Human Genome Sciences, Inc. | Menschlicher Tumornekrosefaktor Delta und Ypsilon |
| JP2004536579A (ja) | 2001-04-13 | 2004-12-09 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | 血管内皮増殖因子２ |
| US7064189B2 (en) | 2001-05-25 | 2006-06-20 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
| US20080194481A1 (en) | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
| AU2002364586A1 (en) | 2001-12-21 | 2003-07-30 | Delta Biotechnology Limited | Albumin fusion proteins |
| WO2003066824A2 (en) | 2002-02-07 | 2003-08-14 | Aventis Behring Gmbh | Albumin-fused kunitz domain peptides |
| HUE027902T2 (en) | 2004-02-09 | 2016-11-28 | Human Genome Sciences Inc Corp Service Company | Albumin fusion proteins |
| US7973139B2 (en) | 2004-03-26 | 2011-07-05 | Human Genome Sciences, Inc. | Antibodies against nogo receptor |
| US9505823B2 (en) | 2006-08-07 | 2016-11-29 | TEV A Biopharmaceuticals USA, Inc. | Albumin-insulin fusion proteins |
| US9540426B2 (en) | 2009-10-06 | 2017-01-10 | Bristol-Myers Squibb Company | Mammalian cell culture processes for protein production |
| EP2325322A1 (de) | 2009-11-23 | 2011-05-25 | 4-Antibody AG | Retrovirusvektorpartikel und Verfahren zu deren Erzeugung und Verwendung |
| WO2012095514A1 (en) | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
| AU2012222833B2 (en) | 2011-03-03 | 2017-03-16 | Zymeworks Inc. | Multivalent heteromultimer scaffold design and constructs |
| US20140356863A1 (en) | 2011-11-21 | 2014-12-04 | Bristol-Myers Squibb Company | Methods for determining the susceptibility of a virus to an attachment inhibitor |
| US9657310B2 (en) | 2012-04-27 | 2017-05-23 | Jcr Pharmaceuticals Co., Ltd. | Expression vector |
| EP2674495A1 (de) * | 2012-06-14 | 2013-12-18 | Sanofi | CHO-Expressionssystem |
| WO2014012082A2 (en) | 2012-07-13 | 2014-01-16 | Zymeworks Inc. | Multivalent heteromultimer scaffold design an constructs |
| JP2015531244A (ja) | 2012-10-15 | 2015-11-02 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | タンパク質を製造するための哺乳動物細胞培養方法 |
| WO2014182970A1 (en) | 2013-05-08 | 2014-11-13 | Zymeworks Inc. | Bispecific her2 and her3 antigen binding constructs |
| CA2874083C (en) | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| WO2016130734A1 (en) | 2015-02-11 | 2016-08-18 | Bristol-Myers Squibb Company | Use of phenolic antioxidants in cell culture for the production of proteins |
| WO2017083224A1 (en) | 2015-11-09 | 2017-05-18 | Bristol-Myers Squibb Company | Methods to manipulate quality attributes of polypeptides produced in cho cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601597D0 (en) * | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| EP0319206A3 (de) * | 1987-11-30 | 1990-04-18 | Berlex Laboratories, Inc. | Gen-Vermehrung |
| GB8809129D0 (en) * | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
-
1989
- 1989-10-25 GB GB898924021A patent/GB8924021D0/en active Pending
-
1990
- 1990-10-25 AU AU66299/90A patent/AU6629990A/en not_active Abandoned
- 1990-10-25 JP JP02514839A patent/JP3073009B2/ja not_active Expired - Lifetime
- 1990-10-25 DE DE69030768T patent/DE69030768T2/de not_active Expired - Lifetime
- 1990-10-25 ES ES90916069T patent/ES2104616T3/es not_active Expired - Lifetime
- 1990-10-25 CA CA002071543A patent/CA2071543C/en not_active Expired - Lifetime
- 1990-10-25 AT AT90916069T patent/ATE153383T1/de not_active IP Right Cessation
- 1990-10-25 WO PCT/GB1990/001640 patent/WO1991006657A1/en not_active Ceased
- 1990-10-25 DK DK90916069.9T patent/DK0491875T3/da active
- 1990-10-25 EP EP90916069A patent/EP0491875B1/de not_active Expired - Lifetime
-
1997
- 1997-05-22 GR GR970400941T patent/GR3023510T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB8924021D0 (en) | 1989-12-13 |
| CA2071543C (en) | 2005-02-22 |
| GR3023510T3 (en) | 1997-08-29 |
| ES2104616T3 (es) | 1997-10-16 |
| WO1991006657A1 (en) | 1991-05-16 |
| AU6629990A (en) | 1991-05-31 |
| EP0491875B1 (de) | 1997-05-21 |
| CA2071543A1 (en) | 1991-04-26 |
| EP0491875A1 (de) | 1992-07-01 |
| JPH05504050A (ja) | 1993-07-01 |
| JP3073009B2 (ja) | 2000-08-07 |
| DE69030768D1 (de) | 1997-06-26 |
| DK0491875T3 (da) | 1997-06-16 |
| DE69030768T2 (de) | 1997-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| EELA | Cancelled due to lapse of time |