ATE153383T1 - Rekombinante dna-methode und vektoren, die dafür benutzt werden - Google Patents

Rekombinante dna-methode und vektoren, die dafür benutzt werden

Info

Publication number
ATE153383T1
ATE153383T1 AT90916069T AT90916069T ATE153383T1 AT E153383 T1 ATE153383 T1 AT E153383T1 AT 90916069 T AT90916069 T AT 90916069T AT 90916069 T AT90916069 T AT 90916069T AT E153383 T1 ATE153383 T1 AT E153383T1
Authority
AT
Austria
Prior art keywords
gene
glutamine
recombinant dna
vectors used
dna method
Prior art date
Application number
AT90916069T
Other languages
English (en)
Inventor
Christopher Robert Bebbington
Geoffrey Thomas Yarranton
Original Assignee
Celltech Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Therapeutics Ltd filed Critical Celltech Therapeutics Ltd
Application granted granted Critical
Publication of ATE153383T1 publication Critical patent/ATE153383T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT90916069T 1989-10-25 1990-10-25 Rekombinante dna-methode und vektoren, die dafür benutzt werden ATE153383T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898924021A GB8924021D0 (en) 1989-10-25 1989-10-25 Recombinant dna method and vectors for the use therein

Publications (1)

Publication Number Publication Date
ATE153383T1 true ATE153383T1 (de) 1997-06-15

Family

ID=10665141

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90916069T ATE153383T1 (de) 1989-10-25 1990-10-25 Rekombinante dna-methode und vektoren, die dafür benutzt werden

Country Status (11)

Country Link
EP (1) EP0491875B1 (de)
JP (1) JP3073009B2 (de)
AT (1) ATE153383T1 (de)
AU (1) AU6629990A (de)
CA (1) CA2071543C (de)
DE (1) DE69030768T2 (de)
DK (1) DK0491875T3 (de)
ES (1) ES2104616T3 (de)
GB (1) GB8924021D0 (de)
GR (1) GR3023510T3 (de)
WO (1) WO1991006657A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597886B2 (en) 1994-11-07 2009-10-06 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
WO1997046589A2 (en) 1996-06-07 1997-12-11 Neorx Corporation Humanized antibodies that bind to the same antigen as bound by antibody nr-lu-13, and their use in pretargeting methods
EP1803730A1 (de) 2000-04-12 2007-07-04 Human Genome Sciences, Inc. Albuminfusionsproteine
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
EP1294949A4 (de) 2000-06-15 2004-08-25 Human Genome Sciences Inc Menschlicher tumornekrosefaktor delta und epsilon
EP1385864B1 (de) 2001-04-13 2010-06-09 Human Genome Sciences, Inc. Anti-VEGF-2 Antikörper
ES2437992T3 (es) 2001-05-25 2014-01-15 Human Genome Sciences, Inc. Anticuerpos que se unen inmunoespecíficamente a los receptores de TRAIL
US20080194481A1 (en) 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
EP1997829A1 (de) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin Fusionsproteine
JP2005538932A (ja) 2002-02-07 2005-12-22 アベンティス、ベーリング、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング アルブミン融合クニッツドメインペプチド
HUE027902T2 (en) 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
EP1786463A4 (de) 2004-03-26 2009-05-20 Human Genome Sciences Inc Antikörper gegen nogo-rezeptor
EP2054437A2 (de) 2006-08-07 2009-05-06 Teva Biopharmaceuticals USA, Inc. Albumin-insulin-fusionsproteine
US9540426B2 (en) 2009-10-06 2017-01-10 Bristol-Myers Squibb Company Mammalian cell culture processes for protein production
EP2325322A1 (de) 2009-11-23 2011-05-25 4-Antibody AG Retrovirusvektorpartikel und Verfahren zu deren Erzeugung und Verwendung
WO2012095514A1 (en) 2011-01-14 2012-07-19 Vivalis Recombinant protein production system
CN103732628B (zh) 2011-03-03 2017-06-23 酵活有限公司 多价杂多聚体骨架设计和构建体
WO2013078118A1 (en) 2011-11-21 2013-05-30 Bristol-Myers Squibb Company Methods for determining the susceptibility of a virus to an attachment inhibitor
JP6279466B2 (ja) 2012-04-27 2018-02-14 Jcrファーマ株式会社 新規な発現ベクター
EP2674495A1 (de) 2012-06-14 2013-12-18 Sanofi CHO-Expressionssystem
CA2878640C (en) 2012-07-13 2023-10-24 Zymeworks Inc. Multivalent heteromultimer scaffold design and constructs
JP2015531244A (ja) 2012-10-15 2015-11-02 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company タンパク質を製造するための哺乳動物細胞培養方法
CA2910945A1 (en) 2013-05-08 2014-11-13 Zymeworks Inc. Bispecific her2 and her3 antigen binding constructs
CA2874083C (en) 2014-12-05 2024-01-02 Universite Laval Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases
US10590457B2 (en) 2015-02-11 2020-03-17 Bristol Myers-Squibb Company Compositions for cell culture and methods of using the same
CN108350416A (zh) 2015-11-09 2018-07-31 百时美施贵宝公司 操纵在cho细胞中产生的多肽的品质属性的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601597D0 (en) * 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
EP0319206A3 (de) * 1987-11-30 1990-04-18 Berlex Laboratories, Inc. Gen-Vermehrung
GB8809129D0 (en) * 1988-04-18 1988-05-18 Celltech Ltd Recombinant dna methods vectors and host cells

Also Published As

Publication number Publication date
EP0491875A1 (de) 1992-07-01
EP0491875B1 (de) 1997-05-21
GB8924021D0 (en) 1989-12-13
DK0491875T3 (da) 1997-06-16
WO1991006657A1 (en) 1991-05-16
JP3073009B2 (ja) 2000-08-07
CA2071543C (en) 2005-02-22
GR3023510T3 (en) 1997-08-29
CA2071543A1 (en) 1991-04-26
DE69030768D1 (de) 1997-06-26
DE69030768T2 (de) 1997-10-16
JPH05504050A (ja) 1993-07-01
AU6629990A (en) 1991-05-31
ES2104616T3 (es) 1997-10-16

Similar Documents

Publication Publication Date Title
ATE153383T1 (de) Rekombinante dna-methode und vektoren, die dafür benutzt werden
Kaiser et al. Methods in yeast genetics
Lucibello et al. Periodic cdc25C transcription is mediated by a novel cell cycle‐regulated repressor element (CDE).
DK639689D0 (da) Indfoering af dna i celler
NO964445L (no) DNA-sekvens, vektor, vertscelle og fremgangsmåte for transfeksjon av hematopoeseceller med eksogen DNA
DE69524105D1 (de) Verwendung von rna-polymerase zur verbesserung von nukeinsaeure-amplifikationsverfahren
JP2008086326A (ja) ゲノム性要素を使用する遺伝子の操作および発現
ATE198355T1 (de) Alpha-amidierende enzymzusammensetzungen und verfahren zu deren herstellung und verwendung
DE3889665D1 (de) Serumfreie wachstumsmedien für insektenzellen und expression von produkten damit.
ATE120237T1 (de) Rekombinante dns-verfahren, verktoren und wirtszellen.
GB8810400D0 (en) Analysing polynucleotide sequences
DK101385A (da) Molekylaer kloning og ekspression i industrielle mikroorganismearter
MY101599A (en) Expression of polypeptides in yeast
IL74544A0 (en) Sv40 expression vector containing hbxag as an expression marker
Hirsch et al. Comparison of abundant cytosol proteins in rat liver, Novikoff hepatoma, and Morris hepatoma by two-dimensional gel electrophoresis
DE69033961D1 (de) Zellinien, die einen biologisch aktiven faktor-ix exprimieren
IL65732A (en) Diaphragm,in particular for electrolysis cell,process for the preparation thereof,and an electrolytic cell comprising the same
DE3571646D1 (en) Process for the amplification of the expression of a determined gene in bacillus subtilis and strains obtained
Lau et al. Proteins of transcriptionally active and inactive chromatin from Friend erythroleukemia cells
CA2231745A1 (en) In-vitro transcription processes for screening natural products and other chemical substances
DE3684017D1 (de) Vielfach amplifizierbare vektoren fuer hohe expression exogener dns.
MX9600860A (es) Metodo para detectar polimorfismo de gen p4501a2 de citocromo humano.
IL83435A (en) Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector
Jones Sensitivity of transcription by purified Streptomyces antibioticus RNA polymerase to actinomycin
Ogryzko et al. Influence of DNA superhelicity on transcription of T 4 cloned genes.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time