ATE154345T1 - Indol-sulfonamide als antitumormittel - Google Patents

Indol-sulfonamide als antitumormittel

Info

Publication number: ATE154345T1
Authority: AT; Austria
Prior art keywords: tumor agents; indolinesulfonamide; indolesulfonamide; chem; derivatives
Prior art date: 1993-03-10

Application number

AT94301671T

Other languages

English (en)

Inventor

Gerald Burr Grindey

Cora Sue Grossman

James Jeffry Howbert

James Edward Ray

John Eldon Toth

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-10

Filing date

1994-03-09

Publication date

1997-06-15

1994-03-09 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1997-06-15 Application granted granted Critical

1997-06-15 Publication of ATE154345T1 publication Critical patent/ATE154345T1/de

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94301671T 1993-03-10 1994-03-09 Indol-sulfonamide als antitumormittel ATE154345T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2909593A	1993-03-10	1993-03-10

Publications (1)

Publication Number	Publication Date
ATE154345T1 true ATE154345T1 (de)	1997-06-15

Family

ID=21847185

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94301671T ATE154345T1 (de)	1993-03-10	1994-03-09	Indol-sulfonamide als antitumormittel

Country Status (20)

Country	Link
EP (1)	EP0614887B1 (de)
JP (1)	JPH08507532A (de)
KR (1)	KR960700710A (de)
AT (1)	ATE154345T1 (de)
AU (1)	AU687042B2 (de)
BR (1)	BR9405997A (de)
CA (1)	CA2157801A1 (de)
CZ (1)	CZ232695A3 (de)
DE (1)	DE69403695T2 (de)
DK (1)	DK0614887T3 (de)
ES (1)	ES2102774T3 (de)
FI (1)	FI954213L (de)
GR (1)	GR3023827T3 (de)
HU (1)	HU218660B (de)
NO (1)	NO953557L (de)
NZ (1)	NZ263080A (de)
PL (1)	PL310558A1 (de)
RU (1)	RU2127259C1 (de)
WO (1)	WO1994020101A1 (de)
ZA (1)	ZA941500B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU709107B2 (en) *	1996-08-22	1999-08-19	Dong Wha Pharmaceutical Industrial Co., Ltd.	Arylsulfonylimidazolone derivatives as an antitumor agent
JP2000247949A (ja) *	1999-02-26	2000-09-12	Eisai Co Ltd	スルホンアミド含有インドール化合物
DE19919793A1 (de)	1999-04-30	2000-11-02	Bayer Ag	Neue Sulfonamide
DE60316984T2 (de) *	2002-11-22	2008-07-17	Eli Lilly And Co., Indianapolis	Benzoylsulfonamide als antitumor-mittel
TWI315304B (en) *	2006-08-31	2009-10-01	Univ Taipei Medical	Indoline-sulfonamides compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1240866B (de) *	1961-06-29	1967-05-24	Heyden Chem Fab	Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
IL80032A (en) *	1985-09-23	1992-07-15	Lilly Co Eli	Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
US5116874A (en) *	1985-09-23	1992-05-26	Eli Lilly And Company	Anti-tumor method and compounds
CA1331464C (en) *	1987-05-12	1994-08-16	Eli Lilly And Company	Anti-tumor method and compounds
NZ238911A (en) *	1990-07-17	1993-10-26	Lilly Co Eli	Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor
US5169860A (en) *	1992-03-13	1992-12-08	Eli Lilly And Company	Antitumor compositions and methods of treatment

1994
- 1994-03-03 ZA ZA941500A patent/ZA941500B/xx unknown
- 1994-03-09 DK DK94301671.7T patent/DK0614887T3/da active
- 1994-03-09 ES ES94301671T patent/ES2102774T3/es not_active Expired - Lifetime
- 1994-03-09 EP EP94301671A patent/EP0614887B1/de not_active Expired - Lifetime
- 1994-03-09 AT AT94301671T patent/ATE154345T1/de not_active IP Right Cessation
- 1994-03-09 DE DE69403695T patent/DE69403695T2/de not_active Expired - Fee Related
- 1994-03-10 NZ NZ263080A patent/NZ263080A/en unknown
- 1994-03-10 FI FI954213A patent/FI954213L/fi unknown
- 1994-03-10 KR KR1019950703798A patent/KR960700710A/ko not_active Ceased
- 1994-03-10 WO PCT/US1994/002606 patent/WO1994020101A1/en not_active Ceased
- 1994-03-10 CA CA002157801A patent/CA2157801A1/en not_active Abandoned
- 1994-03-10 JP JP6520310A patent/JPH08507532A/ja active Pending
- 1994-03-10 RU RU95122639A patent/RU2127259C1/ru active
- 1994-03-10 BR BR9405997A patent/BR9405997A/pt not_active Application Discontinuation
- 1994-03-10 AU AU63638/94A patent/AU687042B2/en not_active Ceased
- 1994-03-10 HU HU9502627A patent/HU218660B/hu not_active IP Right Cessation
- 1994-03-10 CZ CZ952326A patent/CZ232695A3/cs unknown
- 1994-03-10 PL PL94310558A patent/PL310558A1/xx unknown
1995
- 1995-09-08 NO NO953557A patent/NO953557L/no unknown
1997
- 1997-06-19 GR GR970401465T patent/GR3023827T3/el unknown

Also Published As

Publication number	Publication date
EP0614887A1 (de)	1994-09-14
BR9405997A (pt)	1995-12-19
AU6363894A (en)	1994-09-26
EP0614887B1 (de)	1997-06-11
FI954213A0 (fi)	1995-09-08
GR3023827T3 (en)	1997-09-30
HU218660B (hu)	2000-10-28
CZ232695A3 (en)	1996-01-17
WO1994020101A1 (en)	1994-09-15
HUT72897A (en)	1996-06-28
HU9502627D0 (en)	1995-11-28
AU687042B2 (en)	1998-02-19
ZA941500B (en)	1995-09-04
RU2127259C1 (ru)	1999-03-10
FI954213A7 (fi)	1995-10-11
NZ263080A (en)	1996-12-20
CA2157801A1 (en)	1994-09-15
KR960700710A (ko)	1996-02-24
NO953557L (no)	1995-11-02
PL310558A1 (en)	1995-12-27
DE69403695D1 (de)	1997-07-17
DK0614887T3 (da)	1997-10-20
JPH08507532A (ja)	1996-08-13
FI954213L (fi)	1995-10-11
DE69403695T2 (de)	1997-10-30
NO953557D0 (no)	1995-09-08
ES2102774T3 (es)	1997-08-01

Legal Events

Date	Code	Title	Description
1997-12-15	UEP	Publication of translation of european patent specification
2002-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ITMI921203A1 (it)	1993-11-19	Derivati di s-triazina come agenti fotostabilizzanti
DK0870768T3 (da)	2002-07-01	Azaindol-ethylaminderivater som nikotinacetylcholinreceptor-bindingsmidler
TW290546B (de)	1996-11-11
GR3036455T3 (en)	2001-11-30	Atherosclerosis treatment
DE69429708D1 (de)	2002-03-14	Galanthamin Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Medikamente
DK0918776T3 (da)	2004-07-12	Totalsyntese af antitumor acylfulvener
ATE172463T1 (de)	1998-11-15	Pyrrolocarbazol
ATE154345T1 (de)	1997-06-15	Indol-sulfonamide als antitumormittel
DK0405436T3 (da)	1995-12-11	Dihetero-nitrogen-holdige cycloheteroethanoanthracenderivater som antipsykotiske midler
GR3023757T3 (en)	1997-09-30	Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents.
HUT70761A (en)	1995-10-30	Alkyl derivatives of trazodone having action for central nervous system, pharmaceutical compositions for preparing thereof
ATE59041T1 (de)	1990-12-15	Hexahydropyrrolo(2,1-a)isochinolinderivate.
FI912499A0 (fi)	1991-05-23	Pyrido/3,4-b/pyrrolo/1,2-e//1,4,5/ oxadiazepiner och daermed naerbeslaektade analoger, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
DK0421668T3 (da)	1995-03-20	1,4-dihydro-4-oxo-3-quinolinderivater som selektivt toksiske, antibakterielle midler til pattedyr
EP0443474A3 (en)	1992-04-22	1-phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents