ATE155685T1 - Derivate des 6-amino-octahydro-indolizintriols - Google Patents

Derivate des 6-amino-octahydro-indolizintriols

Info

Publication number: ATE155685T1
Authority: AT; Austria
Prior art keywords: amino; octahydro; derivatives; triole; indolizine
Prior art date: 1990-06-04

Application number

AT91909495T

Other languages

English (en)

Inventor

Paul S Liu

Mohinder S Kang

Original Assignee

Merrell Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-04

Filing date

1991-05-08

Publication date

1997-08-15

1991-05-08 Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc

1997-08-15 Application granted granted Critical

1997-08-15 Publication of ATE155685T1 publication Critical patent/ATE155685T1/de

Links

DPBJLNMVJTYHJR-UHFFFAOYSA-N 1,2,3,5,6,7,8,8a-octahydroindolizin-6-amine Chemical class C1C(N)CCC2CCCN21 DPBJLNMVJTYHJR-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 abstract 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 abstract 1
102000002268 Hexosaminidases Human genes 0.000 abstract 1
108010000540 Hexosaminidases Proteins 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
-1 ester derivatives of 6-amino-octahydro-1,7,8-indolizinetriol Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cosmetics (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)

AT91909495T 1990-06-04 1991-05-08 Derivate des 6-amino-octahydro-indolizintriols ATE155685T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/532,522 US5079254A (en)	1990-06-04	1990-06-04	Derivatives of 6-aminooctahydroindolizinetriol

Publications (1)

Publication Number	Publication Date
ATE155685T1 true ATE155685T1 (de)	1997-08-15

Family

ID=24122149

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91909495T ATE155685T1 (de)	1990-06-04	1991-05-08	Derivate des 6-amino-octahydro-indolizintriols

Country Status (15)

Country	Link
US (1)	US5079254A (de)
EP (1)	EP0532530B1 (de)
JP (1)	JP3019265B2 (de)
KR (1)	KR100195421B1 (de)
AT (1)	ATE155685T1 (de)
AU (1)	AU641771B2 (de)
CA (1)	CA2082820C (de)
DE (1)	DE69126978T2 (de)
DK (1)	DK0532530T3 (de)
ES (1)	ES2106080T3 (de)
FI (1)	FI97226C (de)
GR (1)	GR3025044T3 (de)
HU (1)	HU212579B (de)
NO (1)	NO300686B1 (de)
WO (1)	WO1991018598A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995013538A1 (en) *	1993-11-12	1995-05-18	Operon Technologies, Inc.	Methods of producing and screening complex chemical libraries
AU1562895A (en) *	1994-01-12	1995-08-01	Massachusetts Institute Of Technology	Process for making xanthene or cubane based compounds, and protease inhibitors
US20070066543A1 (en) *	2003-05-22	2007-03-22	The Hospital For Sick Children	Treatment of tay sachs or sandhoff diseases by enhancing hexosaminidase activity
JP2007518814A (ja) *	2004-01-20	2007-07-12	ザ・スクリップス・リサーチ・インスティテュート	グリコシダーゼ阻害剤によるほ乳類での変性軟骨症の治療
KR100858512B1 (ko)	2007-03-29	2008-09-12	포항공과대학교 산학협력단	헥소스아미니데이즈 활성 저해 방법
US8541441B2 (en) *	2008-08-01	2013-09-24	Simon Fraser University	Selective glycosidase inhibitors and uses thereof
TWI572609B (zh)	2010-12-23	2017-03-01	默沙東藥廠	選擇性醣苷酶抑制劑及其用途
EP2691407B1 (de)	2011-03-31	2017-02-22	Alectos Therapeutics Inc.	Selektive glycosidasehemmer und ihre verwendung
US9701693B2 (en)	2011-06-27	2017-07-11	Alectos Therapeutics Inc.	Selective glycosidase inhibitors and uses thereof
EP2890675A4 (de)	2012-08-31	2016-01-13	Alectos Therapeutics Inc	Glycosidasehemmer und verwendungen davon
WO2014032185A1 (en)	2012-08-31	2014-03-06	Alectos Therapeutics Inc.	Glycosidase inhibitors and uses thereof
RU2672873C2 (ru)	2012-10-31	2018-11-20	Алектос Терапьютикс Инк.	Ингибиторы гликозидаз и их применения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5973519A (ja) *	1982-09-17	1984-04-25	Fujisawa Pharmaceut Co Ltd	スワインソニンの製造法およびそれを含む免疫調整剤
GB8429810D0 (en) *	1984-11-26	1985-01-03	Fujisawa Pharmaceutical Co	Indolizidine derivatives
JPS61277685A (ja) *	1985-05-31	1986-12-08	Fujisawa Pharmaceut Co Ltd	新規インドリジジン誘導体、その製造法およびそれを含有する組成物
DE3620645A1 (de) *	1985-12-20	1987-07-02	Bayer Ag	3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
CA1315276C (en) *	1987-07-02	1993-03-30	Paul S. Liu	Castanospermine esters and glycosides
JPH01129182A (ja) *	1987-11-16	1989-05-22	Tokyo Keiki Co Ltd	波動伝搬時間測定装置
JPH01277685A (ja) *	1988-04-28	1989-11-08	Hitachi Ltd	ピストンポンプ

1990
- 1990-06-04 US US07/532,522 patent/US5079254A/en not_active Expired - Lifetime
1991
- 1991-05-08 JP JP3509415A patent/JP3019265B2/ja not_active Expired - Lifetime
- 1991-05-08 WO PCT/US1991/003179 patent/WO1991018598A1/en not_active Ceased
- 1991-05-08 HU HU9203829A patent/HU212579B/hu not_active IP Right Cessation
- 1991-05-08 AT AT91909495T patent/ATE155685T1/de not_active IP Right Cessation
- 1991-05-08 AU AU78743/91A patent/AU641771B2/en not_active Ceased
- 1991-05-08 ES ES91909495T patent/ES2106080T3/es not_active Expired - Lifetime
- 1991-05-08 DK DK91909495.3T patent/DK0532530T3/da active
- 1991-05-08 DE DE69126978T patent/DE69126978T2/de not_active Expired - Lifetime
- 1991-05-08 KR KR1019920703085A patent/KR100195421B1/ko not_active Expired - Fee Related
- 1991-05-08 CA CA002082820A patent/CA2082820C/en not_active Expired - Lifetime
- 1991-05-08 EP EP91909495A patent/EP0532530B1/de not_active Expired - Lifetime
1992
- 1992-11-19 FI FI925260A patent/FI97226C/fi not_active IP Right Cessation
- 1992-12-03 NO NO924670A patent/NO300686B1/no not_active IP Right Cessation
1997
- 1997-10-15 GR GR970402690T patent/GR3025044T3/el unknown

Also Published As

Publication number	Publication date
CA2082820A1 (en)	1991-12-05
ES2106080T3 (es)	1997-11-01
FI925260A0 (fi)	1992-11-19
DE69126978D1 (de)	1997-08-28
FI925260L (fi)	1992-11-19
NO924670L (no)	1992-12-03
FI97226B (fi)	1996-07-31
US5079254A (en)	1992-01-07
NO300686B1 (no)	1997-07-07
HU9203829D0 (en)	1993-03-29
DK0532530T3 (da)	1997-08-25
KR100195421B1 (ko)	1999-06-15
HUT62585A (en)	1993-05-28
JP3019265B2 (ja)	2000-03-13
HU212579B (en)	1996-08-29
EP0532530A4 (en)	1993-05-26
EP0532530B1 (de)	1997-07-23
AU7874391A (en)	1991-12-31
NO924670D0 (no)	1992-12-03
AU641771B2 (en)	1993-09-30
EP0532530A1 (de)	1993-03-24
FI97226C (fi)	1996-11-11
KR930700502A (ko)	1993-03-15
DE69126978T2 (de)	1997-11-27
JPH05507474A (ja)	1993-10-28
WO1991018598A1 (en)	1991-12-12
GR3025044T3 (en)	1998-01-30
CA2082820C (en)	2002-01-22

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Legal Events

Date	Code	Title	Description
2005-02-15	REN	Ceased due to non-payment of the annual fee