ATE156188T1 - Kainatebindende, menschliche cns-rezeptoren der eaa5-familie - Google Patents

Kainatebindende, menschliche cns-rezeptoren der eaa5-familie

Info

Publication number: ATE156188T1
Authority: AT; Austria
Prior art keywords: kainate; family; receptors; eaa5; eaa
Prior art date: 1992-09-17

Application number

AT93307325T

Other languages

English (en)

Inventor

Rajender Kamboj

Candace E Elliott

Stephen L Nutt

Original Assignee

Allelix Biopharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-17

Filing date

1993-09-16

Publication date

1997-08-15

1993-09-16 Application filed by Allelix Biopharma filed Critical Allelix Biopharma

1997-08-15 Application granted granted Critical

1997-08-15 Publication of ATE156188T1 publication Critical patent/ATE156188T1/de

Links

102000005962 receptors Human genes 0.000 title abstract 7
108020003175 receptors Proteins 0.000 title abstract 7
102100022767 Glutamate receptor ionotropic, kainate 3 Human genes 0.000 title 1
101000903337 Homo sapiens Glutamate receptor ionotropic, kainate 3 Proteins 0.000 title 1
239000003257 excitatory amino acid Substances 0.000 abstract 2
230000002461 excitatory amino acid Effects 0.000 abstract 2
239000012528 membrane Substances 0.000 abstract 2
VLSMHEGGTFMBBZ-OOZYFLPDSA-M Kainate Chemical compound CC(=C)[C@H]1C[NH2+][C@H](C([O-])=O)[C@H]1CC([O-])=O VLSMHEGGTFMBBZ-OOZYFLPDSA-M 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229930195712 glutamate Natural products 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1
230000005062 synaptic transmission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT93307325T 1992-09-17 1993-09-16 Kainatebindende, menschliche cns-rezeptoren der eaa5-familie ATE156188T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US94521092A	1992-09-17	1992-09-17

Publications (1)

Publication Number	Publication Date
ATE156188T1 true ATE156188T1 (de)	1997-08-15

Family

ID=25482790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93307325T ATE156188T1 (de)	1992-09-17	1993-09-16	Kainatebindende, menschliche cns-rezeptoren der eaa5-familie

Country Status (8)

Country	Link
US (2)	US6333161B1 (de)
EP (1)	EP0588642B1 (de)
JP (1)	JPH06205680A (de)
AT (1)	ATE156188T1 (de)
CA (1)	CA2105804C (de)
DE (1)	DE69312608T2 (de)
DK (1)	DK0588642T3 (de)
ES (1)	ES2105122T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2316616A (en) *	1996-09-02	1998-03-04	Lilly Industries Ltd	Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders
ES2172359B1 (es) *	1999-02-04	2003-11-01	Univ Pais Vasco	Peptido capaz de inducir anticuerpos contra la subunidad ka1 de los receptores de kainato de mamiferos, anticuerpo policlonal contra dicha subunidad ka1 y un procedimiento para su obtencion.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE265528T1 (de) *	1989-10-27	2004-05-15	Salk Inst For Biological Studi	Rezeptorverbindungen von glutamin und herstellung
NZ240921A (en)	1990-12-12	1994-06-27	Zymogenetics Inc	G protein coupled glutamate receptor (neurotransmitters), recombinant production
ATE191747T1 (de) *	1991-08-26	2000-04-15	Allelix Biopharma	Menschlicher ka-1 rezeptor, rezeptor aus der eaa1-familie (excitatory amino acid) mit hoher affinität für kainat
ES2148166T3 (es) *	1991-08-27	2000-10-16	Nps Allelix Corp	Receptor de ka-2 humano, un receptor de alta afinidad de cainato de la familia eaa2 (aminoacidos excitaddores).

1993
- 1993-09-09 CA CA002105804A patent/CA2105804C/en not_active Expired - Fee Related
- 1993-09-16 ES ES93307325T patent/ES2105122T3/es not_active Expired - Lifetime
- 1993-09-16 EP EP93307325A patent/EP0588642B1/de not_active Expired - Lifetime
- 1993-09-16 AT AT93307325T patent/ATE156188T1/de active
- 1993-09-16 DK DK93307325.6T patent/DK0588642T3/da active
- 1993-09-16 DE DE69312608T patent/DE69312608T2/de not_active Expired - Fee Related
- 1993-09-17 JP JP5255037A patent/JPH06205680A/ja active Pending
1994
- 1994-01-06 US US08/178,019 patent/US6333161B1/en not_active Expired - Fee Related
1995
- 1995-01-24 US US08/377,503 patent/US6322999B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0588642A1 (de)	1994-03-23
US6333161B1 (en)	2001-12-25
DE69312608T2 (de)	1997-12-04
DE69312608D1 (de)	1997-09-04
US6322999B1 (en)	2001-11-27
JPH06205680A (ja)	1994-07-26
EP0588642B1 (de)	1997-07-30
ES2105122T3 (es)	1997-10-16
CA2105804C (en)	2003-04-29
DK0588642T3 (da)	1997-09-22
CA2105804A1 (en)	1994-03-18

Publication	Publication Date	Title
ZA90944B (en)	1991-10-30	Compounds which are antagonists of excitatory amino acid receptors
ATE522610T1 (de)	2011-09-15	Menschliche, metabotrope glutamatrezeptor- subtypen (hmr6) und verwandte dns-verbindungen
MY131442A (en)	2007-08-30	Excitatory amino acid receptor antagonists
EE9900492A (et)	2000-06-15	II tüüpi TGF-ß retseptori/immunoglobuliini konstantse piirkonna hübriidvalgud
ES2078257T3 (es)	1995-12-16	Antagonistas de aminoacidos excitantes.
DK0617123T3 (da)	1999-12-13	Kainatbindende, humane CNS-receptorer af EAA3-familien
ES2055036T3 (es)	1994-08-16	Antagonistas tetrazolicos de receptores de aminoacidos excitadores.
DK0529994T3 (da)	2001-04-30	Human KA-1-receptor, en kaniat højaffinitetsreceptor af EAA1-familien (excitatoriske aminosyrer)
DE69312608D1 (de)	1997-09-04	Kainatebindende, menschliche CNS-Rezeptoren der EAA5-Familie
GR3033880T3 (en)	2000-11-30	Human KA-2 receptor, a kainate high affinity receptor of the EAA2 (Excitatory Amino Acid) family.
DK0578409T3 (da)	2003-01-27	Kainatbindende humane CNS-receptorer af EAA4-typen
DE69328060D1 (de)	2000-04-20	Angiotensin-II Typ-1 Rezeptor und dessen Herstellung
HU896448D0 (en)	1990-02-28	Process for the preparation of anticoagulant peptides
IL104139A0 (en)	1993-05-13	Recombinant dna compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus
DK210288D0 (da)	1988-04-18	Overproduktion af exocelllulaere proteiner