ATE156833T1 - Verfahren zur herstellung von azt und derivaten davon - Google Patents

Verfahren zur herstellung von azt und derivaten davon

Info

Publication number
ATE156833T1
ATE156833T1 AT94402485T AT94402485T ATE156833T1 AT E156833 T1 ATE156833 T1 AT E156833T1 AT 94402485 T AT94402485 T AT 94402485T AT 94402485 T AT94402485 T AT 94402485T AT E156833 T1 ATE156833 T1 AT E156833T1
Authority
AT
Austria
Prior art keywords
azt
derivatives
producing
makes use
azido
Prior art date
Application number
AT94402485T
Other languages
English (en)
Inventor
Bang-Chi Chen
Sandra L Quinlan
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE156833T1 publication Critical patent/ATE156833T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Casings For Electric Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94402485T 1993-11-15 1994-11-03 Verfahren zur herstellung von azt und derivaten davon ATE156833T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/152,803 US5466787A (en) 1993-11-15 1993-11-15 Process for preparing AZT

Publications (1)

Publication Number Publication Date
ATE156833T1 true ATE156833T1 (de) 1997-08-15

Family

ID=22544519

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94402485T ATE156833T1 (de) 1993-11-15 1994-11-03 Verfahren zur herstellung von azt und derivaten davon

Country Status (16)

Country Link
US (1) US5466787A (de)
EP (1) EP0653437B1 (de)
JP (1) JPH07188279A (de)
KR (1) KR100319127B1 (de)
CN (1) CN1047781C (de)
AT (1) ATE156833T1 (de)
AU (1) AU672533B2 (de)
CA (1) CA2135854A1 (de)
DE (1) DE69404953T2 (de)
DK (1) DK0653437T3 (de)
ES (1) ES2107771T3 (de)
FI (1) FI945321A7 (de)
GR (1) GR3025375T3 (de)
HU (1) HU219478B (de)
IL (1) IL111568A (de)
TW (1) TW432071B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006179A1 (en) * 1995-08-04 1997-02-20 Kobayashi Perfumery Co., Ltd. Process for producing azido nucleoside derivatives
CN1054132C (zh) * 1998-01-05 2000-07-05 华东理工大学 一种从混合物中分离胸苷的方法
CN1055293C (zh) * 1998-10-06 2000-08-09 中国人民解放军第二军医大学 一种β-胸苷的制备方法
JP3674695B2 (ja) 1999-06-07 2005-07-20 東芝ライテック株式会社 放電ランプ、放電ランプ装置
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
CN101376667B (zh) * 2007-08-27 2011-01-12 上海迪赛诺医药发展有限公司 一种合成齐多夫定的中间体及其制备方法和该中间体在合成齐多夫定中的应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB966222A (en) * 1960-04-11 1964-08-06 Nat Res Dev Derivatives of cephalosporin c
GB1080904A (en) * 1963-11-19 1967-08-31 Ciba Ltd Process for the manufacture of desacetyl-u-amino-cephalosporanic acid
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés
GB1531212A (en) * 1974-11-08 1978-11-08 Glaxo Lab Ltd Enzymatic hydrolysis of 3-acyloxymethylceph-3-em-4-carboxylic acids or salts thereof
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US4874751A (en) * 1985-03-16 1989-10-17 Burroughs Wellcome Co. Antibacterial treatment
US5093114A (en) * 1985-03-16 1992-03-03 Burroughs Wellcome Co. Treatment of human viral infections
US4847244A (en) * 1985-09-17 1989-07-11 Burroughs Wellcome Co. Treatment of human viral infections
US4818750A (en) * 1985-09-17 1989-04-04 Burroughs Wellcome Co. Treatment of human viral infections
DE3604873A1 (de) * 1986-02-15 1987-08-20 Basf Ag Verfahren zur herstellung von 2,6-bis (hydroxymethyl)-pyridin-2,6-bis-(n-methylcarbamat)
US5145840A (en) * 1986-06-23 1992-09-08 Burroughs Wellcome Co. Treatment of idiopathic thrombocytopaenic purpura
DE3705794A1 (de) * 1987-02-24 1988-09-01 Bayer Ag Verfahren zur herstellung von 1-(3-azido-2,3-didesoxy-ss-d- erythropentofuranosyl)pyrimidinen sowie neue zwischenprodukte
GB8706176D0 (en) * 1987-03-16 1987-04-23 Wellcome Found Therapeutic nucleosides
FI881413A7 (fi) * 1987-03-25 1988-09-26 The Wellcome Foundation Ltd Menetelmä 3'-atsido-3'-deoksitymidiinin valmistamiseksi.
YU110888A (en) * 1987-06-10 1989-08-31 Wellcome Found Process for obtaining timine derivatives
FR2640267B2 (fr) * 1988-01-19 1992-02-14 Univ Paris Curie Procede de synthese de l'azido-3(prime)-desoxy-3(prime)-thymidine et analogues
US4921950A (en) * 1988-06-09 1990-05-01 Burroughs Wellcome Co. Preparation of 3'azido-3-'-deoxythymidine
US4916218A (en) * 1988-06-09 1990-04-10 Almond Merrick R 1-(β-D-xylofuranosyl)thymine derivatives
US4987224A (en) * 1988-08-02 1991-01-22 University Of Georgia Research Foundation, Inc. Method of preparation of 2',3'-dideoxynucleosides
JP3128080B2 (ja) * 1991-10-02 2001-01-29 日本製紙株式会社 核酸化合物の新規な製造方法
FI90552C (fi) * 1991-10-09 1994-02-25 Leiras Oy Menetelmä nukleosidijohdannaisten valmistamiseksi

Also Published As

Publication number Publication date
HUT69167A (en) 1995-08-28
IL111568A0 (en) 1995-01-24
JPH07188279A (ja) 1995-07-25
DE69404953D1 (de) 1997-09-18
EP0653437B1 (de) 1997-08-13
KR950014133A (ko) 1995-06-15
EP0653437A1 (de) 1995-05-17
IL111568A (en) 2001-06-14
CN1047781C (zh) 1999-12-29
US5466787A (en) 1995-11-14
TW432071B (en) 2001-05-01
DK0653437T3 (da) 1998-03-16
ES2107771T3 (es) 1997-12-01
HU9403255D0 (en) 1995-01-30
GR3025375T3 (en) 1998-02-27
CA2135854A1 (en) 1995-05-16
AU672533B2 (en) 1996-10-03
CN1107847A (zh) 1995-09-06
FI945321L (fi) 1995-05-16
DE69404953T2 (de) 1998-03-26
FI945321A0 (fi) 1994-11-11
AU7880594A (en) 1995-06-01
FI945321A7 (fi) 1995-05-16
KR100319127B1 (ko) 2002-06-20
HU219478B (hu) 2001-04-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee