ATE156842T1 - Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen - Google Patents

Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Info

Publication number: ATE156842T1
Authority: AT; Austria
Prior art keywords: pct; molecular weight; glycosaminoglycans; oligosaccharides; producing
Prior art date: 1992-12-23

Application number

AT94904168T

Other languages

English (en)

Inventor

Gianni Ferrari

Original Assignee

Mediolanum Farmaceutici Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-23

Filing date

1993-12-21

Publication date

1997-08-15

1993-12-21 Application filed by Mediolanum Farmaceutici Srl filed Critical Mediolanum Farmaceutici Srl

1997-08-15 Application granted granted Critical

1997-08-15 Publication of ATE156842T1 publication Critical patent/ATE156842T1/de

Links

229920002683 Glycosaminoglycan Polymers 0.000 title abstract 3
229920001542 oligosaccharide Polymers 0.000 title abstract 2
150000002482 oligosaccharides Chemical class 0.000 title abstract 2
230000004071 biological effect Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
239000004019 antithrombin Substances 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Polymers & Plastics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Materials Engineering (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)

AT94904168T 1992-12-23 1993-12-21 Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen ATE156842T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI922950A IT1256236B (it)	1992-12-23	1992-12-23	Oligosaccaridi aventi attivita' biologica e procedimento per la loro preparazione di glicosaminoglicani

Publications (1)

Publication Number	Publication Date
ATE156842T1 true ATE156842T1 (de)	1997-08-15

Family

ID=11364528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94904168T ATE156842T1 (de)	1992-12-23	1993-12-21	Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Country Status (9)

Country	Link
US (1)	US5705493A (de)
EP (1)	EP0675905B1 (de)
AT (1)	ATE156842T1 (de)
AU (1)	AU5833694A (de)
CA (1)	CA2151610A1 (de)
DE (1)	DE69313138T2 (de)
ES (1)	ES2108418T3 (de)
IT (1)	IT1256236B (de)
WO (1)	WO1994014850A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2004059506A (ja) *	2002-07-29	2004-02-26	Taisho Pharmaceut Co Ltd	セレクチン及びケモカインに作用する過硫酸化オリゴ糖
US20040171819A1 (en)	2002-10-10	2004-09-02	Aventis Pharma S.A.	Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US8021677B2 (en)	2006-05-12	2011-09-20	Gore Enterprise Holdings, Inc.	Immobilized biologically active entities having a high degree of biological activity
US20150011501A1 (en) *	2012-02-17	2015-01-08	Kimflexor, S.L.	Partially depolymerized glycosaminoglycan silver and gold salts
CN114057908A (zh) *	2020-08-08	2022-02-18	烟台东诚药业集团股份有限公司	一种低分子硫酸软骨素钠的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3454560A (en) *	1966-03-01	1969-07-08	Seikagaku Kogyo Co Ltd	Process for the production of chondroitin polysulfate
JPS4942486B1 (de) *	1970-09-21	1974-11-15
FR2482611B1 (fr) *	1980-05-14	1986-03-07	Pharmindustrie	Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
DE3118588C2 (de) *	1981-05-11	1983-07-07	Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München	Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2548672A1 (fr) *	1983-07-04	1985-01-11	Pharmuka Lab	Oligosaccharides sulfates et leur utilisation comme medicaments
IT1208509B (it) *	1985-03-13	1989-07-10	Mediolanum Farmaceutici Srl	Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
IT1213384B (it) *	1986-11-24	1989-12-20	Lab Derivati Organici Mediolan	Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1245761B (it) *	1991-01-30	1994-10-14	Alfa Wassermann Spa	Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.

1992
- 1992-12-23 IT ITMI922950A patent/IT1256236B/it active IP Right Grant
1993
- 1993-12-21 DE DE69313138T patent/DE69313138T2/de not_active Expired - Fee Related
- 1993-12-21 AT AT94904168T patent/ATE156842T1/de not_active IP Right Cessation
- 1993-12-21 CA CA002151610A patent/CA2151610A1/en not_active Abandoned
- 1993-12-21 ES ES94904168T patent/ES2108418T3/es not_active Expired - Lifetime
- 1993-12-21 WO PCT/EP1993/003646 patent/WO1994014850A1/en not_active Ceased
- 1993-12-21 EP EP94904168A patent/EP0675905B1/de not_active Expired - Lifetime
- 1993-12-21 AU AU58336/94A patent/AU5833694A/en not_active Abandoned
- 1993-12-21 US US08/481,282 patent/US5705493A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO1994014850A1 (en)	1994-07-07
DE69313138T2 (de)	1997-12-11
DE69313138D1 (de)	1997-09-18
CA2151610A1 (en)	1994-07-07
AU5833694A (en)	1994-07-19
US5705493A (en)	1998-01-06
EP0675905A1 (de)	1995-10-11
EP0675905B1 (de)	1997-08-13
ITMI922950A0 (it)	1992-12-23
ITMI922950A1 (it)	1994-06-23
ES2108418T3 (es)	1997-12-16
IT1256236B (it)	1995-11-29

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Legal Events

Date	Code	Title	Description
1998-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties