ES2108418T3 - Oligosacaridos con actividad biologica y preparacion de los mismos a partir de glicosaminoglicanos. - Google Patents

Oligosacaridos con actividad biologica y preparacion de los mismos a partir de glicosaminoglicanos.

Info

Publication number
ES2108418T3
ES2108418T3 ES94904168T ES94904168T ES2108418T3 ES 2108418 T3 ES2108418 T3 ES 2108418T3 ES 94904168 T ES94904168 T ES 94904168T ES 94904168 T ES94904168 T ES 94904168T ES 2108418 T3 ES2108418 T3 ES 2108418T3
Authority
ES
Spain
Prior art keywords
preparation
biological activity
same
oligosaccharids
glycosaminoglycans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94904168T
Other languages
English (en)
Inventor
Gianni Ferrari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediolanum Farmaceutici SpA
Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici SpA filed Critical Mediolanum Farmaceutici SpA
Application granted granted Critical
Publication of ES2108418T3 publication Critical patent/ES2108418T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA SIGUIENTE DESCRIPCION DESCUBRE ALGUNOS OLIGOSACARIDOS QUE TIENEN ACTIVIDAD BIOLOGICA Y EL PROCEDIMIENTO PARA LA PREPARACION DE LOS MISMOS A PARTIR DE GLICOSAMINOGLICANOS, QUE PUEDEN ESTAR TAMBIEN SUPER-SULFATADOS, EN PARTICULAR A PARTIR DE CONDROITINAS, DERMATANOS Y MEZCLAS DE GLICOSAMINOGLICANOS QUE TIENEN VARIAS COMPOSICIONES, MEDIANTE REACCIONES DE ELIMINACION (BETA) EN SOLVENTES ORGANICOS O, EN CASO DE GLICOSAMINOGLICANOS SUPER-SULFATADOS, TAMBIEN EN SOLVENTES ACUOSOS, A TRAVES DE UN PROCESO QUE INCLUYE O NO EL AISLAMIENTO DE UN PRODUCTO INTERMEDIO ESTERIFICADO.
ES94904168T 1992-12-23 1993-12-21 Oligosacaridos con actividad biologica y preparacion de los mismos a partir de glicosaminoglicanos. Expired - Lifetime ES2108418T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922950A IT1256236B (it) 1992-12-23 1992-12-23 Oligosaccaridi aventi attivita' biologica e procedimento per la loro preparazione di glicosaminoglicani

Publications (1)

Publication Number Publication Date
ES2108418T3 true ES2108418T3 (es) 1997-12-16

Family

ID=11364528

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94904168T Expired - Lifetime ES2108418T3 (es) 1992-12-23 1993-12-21 Oligosacaridos con actividad biologica y preparacion de los mismos a partir de glicosaminoglicanos.

Country Status (9)

Country Link
US (1) US5705493A (es)
EP (1) EP0675905B1 (es)
AT (1) ATE156842T1 (es)
AU (1) AU5833694A (es)
CA (1) CA2151610A1 (es)
DE (1) DE69313138T2 (es)
ES (1) ES2108418T3 (es)
IT (1) IT1256236B (es)
WO (1) WO1994014850A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004059506A (ja) * 2002-07-29 2004-02-26 Taisho Pharmaceut Co Ltd セレクチン及びケモカインに作用する過硫酸化オリゴ糖
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US8021677B2 (en) 2006-05-12 2011-09-20 Gore Enterprise Holdings, Inc. Immobilized biologically active entities having a high degree of biological activity
CA2861052A1 (en) * 2012-02-17 2013-08-22 Kimflexor, S.L. Partially depolymerized glycosaminoglycan silver and gold salts
CN114057908A (zh) * 2020-08-08 2022-02-18 烟台东诚药业集团股份有限公司 一种低分子硫酸软骨素钠的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454560A (en) * 1966-03-01 1969-07-08 Seikagaku Kogyo Co Ltd Process for the production of chondroitin polysulfate
JPS4942486B1 (es) * 1970-09-21 1974-11-15
FR2482611B1 (fr) * 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2548672A1 (fr) * 1983-07-04 1985-01-11 Pharmuka Lab Oligosaccharides sulfates et leur utilisation comme medicaments
IT1208509B (it) * 1985-03-13 1989-07-10 Mediolanum Farmaceutici Srl Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1245761B (it) * 1991-01-30 1994-10-14 Alfa Wassermann Spa Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.

Also Published As

Publication number Publication date
ITMI922950A0 (it) 1992-12-23
DE69313138D1 (de) 1997-09-18
DE69313138T2 (de) 1997-12-11
ATE156842T1 (de) 1997-08-15
IT1256236B (it) 1995-11-29
AU5833694A (en) 1994-07-19
EP0675905A1 (en) 1995-10-11
ITMI922950A1 (it) 1994-06-23
US5705493A (en) 1998-01-06
EP0675905B1 (en) 1997-08-13
WO1994014850A1 (en) 1994-07-07
CA2151610A1 (en) 1994-07-07

Similar Documents

Publication Publication Date Title
BR8804098A (pt) Compostos,composicoes e processo para reducao da fitotoxidez de plantas de cultura
AR010385A1 (es) Compuesto derivado de propiofenona, proceso para su preparacion, composicion farmaceutica que lo contiene y uso de dicho compuesto.
PT94645A (pt) Processo para a preparacao de derivados de aminopirimidina com actividade fungicida e de composicoes fungicidas que os contem
ES2077869T3 (es) Policitraconimidas y poliitaconimidas que contienen poli(sulfuro).
PT99671A (pt) Processo para a preparacao de heparosanos-n,o-sulfatados e de composicoes farmaceuticas que os contem
BR8000192A (pt) Processo para o melhoramento da solubilidade de substancias ativas de atividade biologica,compostos com solubilidade melhorada e processo para sua preparacao
ES2124373T3 (es) Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico.
ES2113448T3 (es) Catalizador de polimerizacion de olefinas, procedimiento para su preparacion y su utilizacion.
BR9302737A (pt) Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquica
BR8701885A (pt) Processo para preparar um concentrado claro,estavel ao armazenamento,produto assim preparado,processo para preparar um desinfetante e desinfetante produzido pelo mesmo
ES2140565T3 (es) Nuevos derivados de pirazina-carboxamida, su preparacion y su utilizacion en medicamentos.
AR004545A1 (es) Derivados de purin-6-ona, procedimientos para su preparacion, el uso de los mismos en la preparacion de medicamentos, medicamentos que los contieneny un procedimiento para preparar dichos medicamentos
BR8905777A (pt) Processo para preparacao de eteres de ciclohexenonoxima,aplicaveis como herbicidas
PT92025A (pt) Processo para a preparacao de spiro-isoquinolina-pirrolidina-tetronas e seus analogos, uteis como inibidores da reductase da aldose
PT91701A (pt) Processo para a preparacao de esteres nitrato organicos e de composicoes farmaceuticas que os contem, tendo actividade relaxante
FI902248A7 (fi) N-heteroaryyli-4-kinoliiniamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
PT93227A (pt) Processo para a preparacao de tetra-hidro-imidazo-{1,4}-benzodiazepin-2-tionas e de composicoes antivirais que as contem
BR8701139A (pt) Processo para preparacao de um produto polimerico a partir de um fenol,um terpeno e um componente aromatico substituido com vinila,e o dito produto polimerico
MX9304731A (es) Polisacaridos de glucogeno.
ES2108418T3 (es) Oligosacaridos con actividad biologica y preparacion de los mismos a partir de glicosaminoglicanos.
PT87141A (pt) Processo para a preparacao de composicoes de ascomicetos,esquizomicetos e leveduras transformados biofisicamente e de racoes e nutrientes vegetais contendo estas composicoes
BR9302389A (pt) Composto,formulacao farmaceutica e processo para preparar o composto
AU7584891A (en) Treatment of osmotic disturbance with organic osmolytes
BR9000986A (pt) Mistura esterilizante e processo para esterilizar um artigo
ES2113450T3 (es) Poliesterpolioles insaturados y su uso en lacas de poliuretano de dos componentes.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 675905

Country of ref document: ES