ATE157172T1 - Verwendung von monoclonalen rezeptoren gegen oncoproteinen zur überwachung von krebstherapie - Google Patents

Verwendung von monoclonalen rezeptoren gegen oncoproteinen zur überwachung von krebstherapie

Info

Publication number
ATE157172T1
ATE157172T1 AT88310540T AT88310540T ATE157172T1 AT E157172 T1 ATE157172 T1 AT E157172T1 AT 88310540 T AT88310540 T AT 88310540T AT 88310540 T AT88310540 T AT 88310540T AT E157172 T1 ATE157172 T1 AT E157172T1
Authority
AT
Austria
Prior art keywords
sample
pattern
cancer therapy
monitoring cancer
receptors against
Prior art date
Application number
AT88310540T
Other languages
English (en)
Inventor
Henry Lee Niman
Original Assignee
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ligand Pharm Inc filed Critical Ligand Pharm Inc
Application granted granted Critical
Publication of ATE157172T1 publication Critical patent/ATE157172T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT88310540T 1987-11-09 1988-11-09 Verwendung von monoclonalen rezeptoren gegen oncoproteinen zur überwachung von krebstherapie ATE157172T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11882387A 1987-11-09 1987-11-09

Publications (1)

Publication Number Publication Date
ATE157172T1 true ATE157172T1 (de) 1997-09-15

Family

ID=22380954

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88310540T ATE157172T1 (de) 1987-11-09 1988-11-09 Verwendung von monoclonalen rezeptoren gegen oncoproteinen zur überwachung von krebstherapie

Country Status (10)

Country Link
US (1) US20030215894A1 (de)
EP (1) EP0318179B1 (de)
JP (1) JPH03500928A (de)
AT (1) ATE157172T1 (de)
AU (2) AU2497388A (de)
CA (1) CA1339069C (de)
DE (1) DE3856004T2 (de)
ES (1) ES2108679T3 (de)
GR (1) GR3025378T3 (de)
WO (1) WO1989004489A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733738A (en) * 1983-08-17 1998-03-31 Ligand Pharmaceuticals Polypeptide-induced monoclonal receptors to protein ligands
CA1219232A (en) * 1983-08-17 1987-03-17 Richard A. Lerner Polypeptide-induced monoclonal receptors to protein ligands
AU596670B2 (en) * 1986-05-06 1990-05-10 Amgen, Inc. Assays and antibodies for n-myc proteins
JPH04500122A (ja) * 1988-08-12 1992-01-09 プロジェンクス・インコーポレイテッド 蛋白リガンドに対するポリペプチド誘発モノクローナル受容体
GB9103974D0 (en) * 1991-02-26 1991-04-10 Norsk Hydro As Therapeutically useful peptides or peptide fragments
US7115728B1 (en) 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
US6489451B1 (en) 1997-04-10 2002-12-03 Hefei-Siu-Fung Ustc Pharmaceutical Co., Ltd. Antithrombosis enzyme from the snake venom of agkistrodon acutus
AU8588798A (en) 1997-07-25 1999-02-16 Institut Pasteur Human peroxisome proliferator activated receptor gamma (ppargamma) gene re gulatory sequences and uses therefor
WO1999040434A1 (en) * 1998-02-04 1999-08-12 Invitrogen Corporation Microarrays and uses therefor
AU741712B2 (en) * 1998-02-18 2001-12-06 Theryte Limited Treating cancer
US8383799B2 (en) 2006-01-20 2013-02-26 Cell Signaling Technology, Inc. Translocation and mutant ROS kinase in human non-small cell lung carcinoma
EP2671954B1 (de) 2006-01-20 2018-05-16 Cell Signaling Technology, Inc. Translokation und Mutations-ROS-Kinase bei menschlichem nicht-kleinzelligem Lungenkrebs
EP3837035A4 (de) 2018-08-16 2022-05-18 EMD Millipore Corporation Geschlossener bioprozessor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535058A (en) * 1982-10-01 1985-08-13 Massachusetts Institute Of Technology Characterization of oncogenes and assays based thereon
US4798787A (en) * 1984-09-19 1989-01-17 Cetus Corporation Peptide antibodies and their use in detecting oncogene products
EP0206065A3 (de) * 1985-06-27 1989-04-19 James R. Feramisco Verfahren zum Nachweis von oncogenischen und proto-oncogenischen Proteinen in extrazelligen biologischen Flüssigkeiten

Also Published As

Publication number Publication date
US20030215894A1 (en) 2003-11-20
JPH03500928A (ja) 1991-02-28
AU2967792A (en) 1993-02-11
WO1989004489A1 (en) 1989-05-18
ES2108679T3 (es) 1998-01-01
EP0318179A3 (de) 1990-08-01
DE3856004T2 (de) 1997-12-18
AU665591B2 (en) 1996-01-11
DE3856004D1 (de) 1997-09-25
AU2497388A (en) 1989-05-11
CA1339069C (en) 1997-07-29
EP0318179A2 (de) 1989-05-31
GR3025378T3 (en) 1998-02-27
EP0318179B1 (de) 1997-08-20

Similar Documents

Publication Publication Date Title
ATE157172T1 (de) Verwendung von monoclonalen rezeptoren gegen oncoproteinen zur überwachung von krebstherapie
DE69733560D1 (de) TESTVERFAHREN UND REAGENZIEN ZUR QUANTIFIZIERUNG VON hBNP
ATE449342T1 (de) Nachweis von krebs
ATE246378T1 (de) Verfahren zum feststellen der preparationsgüte von objektträgern und proben
ATE159982T1 (de) Antikörper mit modifiziertem kohlenhydratgehalt und verfahren zur herstellung und verwendung
NO904001D0 (no) Fremgangsmaate og anordning for amperometrisk diagnoseanalyse.
ATE114820T1 (de) Verfahren zur bestimmung von durch onkogene verursachten krebs.
CY1112631T1 (el) ΜΕΘΟΔΟΙ ΤΑΥΤΟΠΟΙΗΣΗΣ ΟΓΚΩΝ ΠΟΥ ΑΠΟΚΡΙΝΟΝΤΑΙ ΣΕ ΑΓΩΓΗ ΜΕ ΑΝΤΙΣΩΜΑΤΑ ΑΝΤΙ-ΕrbB2
ES8303072A1 (es) Metodo para diagnosticar la presencia de una enfermedad especifica, una etapa especifica de una enfermedad, o mas aler- gia, en un paciente, a base de la deteccion de la reacciones antigeno-anticuerpo en un substrato.
ATE126354T1 (de) Vorrichtung und verfahren zur bestimmung eines analyten in einer flüssigen probe mittels folgereaktionen.
ATE76689T1 (de) Verfahren fuer die beschaffung interner referenzen zur verwendung in analyt-rezeptor-tests.
CY1108450T1 (el) Μεθοδος για την ανιχνευση ν-τελικου προβνρ
DE68902738D1 (de) Verfahren zur bestimmung mittels strahlungsabsorption von substanzen in absorbierenden und streuenden matrixmaterialien.
DE69807878D1 (de) Erkennung und Modulierung von IAPS und NAIP zur Diagnose und Behandlung von proliferativen Erkrankungen
DE58908905D1 (de) Verfahren zur Bestimmung einer spezifisch bindefähigen Substanz.
ATE107776T1 (de) Verfahren zur bestimmung einer spezifisch bindefähigen substanz.
ATE68600T1 (de) Satz und verfahren zur diagnose der iganephropathie.
DE3485265D1 (de) Verfahren zur bestimmung eines polyvalenten antigens und reagenz hierfuer.
ES2122292T3 (es) Diagnosis precoz de sepsis utilizando interacciones antigeno-anticuerpo amplificadas por quimioluminiscencia de sangre completa.
DE69221104D1 (de) Immunoassay für NCA-BT in Blutproben von Brustkrebspatientinnen
DE69229948D1 (de) hGPIIb-FRAGMENTE UND IHRE VERWENDUNG IN IN-VITRO-VERFAHREN ZUR BESTIMMUNG VON IN VIVO STATTFINDENDEN THROMBOTISCHEN EREIGNISSEN
SU608098A1 (ru) Способ определени влагостойкости непровод щих электрический ток материалов
ATE118617T1 (de) Enzym-quantifizierungstest auf einem docht.
IT1261944B (it) Determinazione rapida dei nuovi biomarkers, cross-link del riassorbimento osseo e del collagene, piridinoline e cheratan-solfato,nei fluidi biologici.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee