ATE157259T1 - Verbesserte adjuvantien und impfstoffe - Google Patents

Verbesserte adjuvantien und impfstoffe

Info

Publication number
ATE157259T1
ATE157259T1 AT91913213T AT91913213T ATE157259T1 AT E157259 T1 ATE157259 T1 AT E157259T1 AT 91913213 T AT91913213 T AT 91913213T AT 91913213 T AT91913213 T AT 91913213T AT E157259 T1 ATE157259 T1 AT E157259T1
Authority
AT
Austria
Prior art keywords
antigen
isotype
present
vaccines
admixed
Prior art date
Application number
AT91913213T
Other languages
English (en)
Inventor
Robert L Hunter
Kuni K Takayama
Original Assignee
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Emory filed Critical Univ Emory
Application granted granted Critical
Publication of ATE157259T1 publication Critical patent/ATE157259T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT91913213T 1990-06-27 1991-06-27 Verbesserte adjuvantien und impfstoffe ATE157259T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54483190A 1990-06-27 1990-06-27
US71680791A 1991-06-21 1991-06-21

Publications (1)

Publication Number Publication Date
ATE157259T1 true ATE157259T1 (de) 1997-09-15

Family

ID=27067746

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913213T ATE157259T1 (de) 1990-06-27 1991-06-27 Verbesserte adjuvantien und impfstoffe

Country Status (17)

Country Link
EP (1) EP0536302B1 (de)
JP (1) JPH0832639B2 (de)
KR (1) KR100218138B1 (de)
CN (1) CN1060027A (de)
AT (1) ATE157259T1 (de)
AU (1) AU655593B2 (de)
BR (1) BR9106601A (de)
CA (1) CA2086097C (de)
DE (1) DE69127445T2 (de)
DK (1) DK0536302T3 (de)
ES (1) ES2104712T3 (de)
GR (1) GR3025341T3 (de)
IE (1) IE912257A1 (de)
IL (1) IL98655A0 (de)
NZ (1) NZ238731A (de)
PT (1) PT98119B (de)
WO (1) WO1992000101A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3723231B2 (ja) * 1991-12-23 2005-12-07 ディミナコ アクチェンゲゼルシャフト アジュバント
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
US5407585A (en) * 1993-08-16 1995-04-18 Exxon Chemical Patents Inc. Method of demulsifying water-in-oil emulsions
GB9326253D0 (en) * 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
EP1181937A3 (de) * 1994-08-09 2004-02-04 Cytrx Corporation Nukleinsäure enthaltender Impfstoff, Impfstoff-adjuvans
US6353055B1 (en) 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
US6221959B1 (en) 1994-11-18 2001-04-24 Supratek Pharma, Inc. Polynucleotide compositions
AU6358898A (en) * 1996-09-09 1998-04-17 Alexander V Kabanov Fluorinated copolymeric pharmaceutical adjuncts
US6248334B1 (en) * 1997-01-08 2001-06-19 Henry M. Jackson Foundation For The Advancement Of Military Medicine Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process
US6368604B1 (en) 1997-09-26 2002-04-09 University Of Maryland Biotechnology Institute Non-pyrogenic derivatives of lipid A
US7297330B2 (en) * 2000-02-04 2007-11-20 Thomas Jefferson University Low dose haptenized tumor cell and tumor cell extract immunotherapy
US7256180B2 (en) 2000-04-28 2007-08-14 Supratek Pharma Inc. Compositions and methods for inducing activation of dendritic cells
CN102580081B (zh) * 2012-02-22 2014-07-02 中国医学科学院医学生物学研究所 Nad、氢氧化铝复合佐剂及含该复合佐剂的疫苗
CN113527417B (zh) * 2021-07-05 2022-09-27 中国医学科学院放射医学研究所 一种含氟基团的自组装多肽纳米佐剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3380726D1 (en) * 1982-06-24 1989-11-23 Japan Chem Res Long-acting composition
US4770874A (en) * 1983-08-22 1988-09-13 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4772466A (en) * 1983-08-22 1988-09-20 Syntex (U.S.A.) Inc. Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants

Also Published As

Publication number Publication date
AU655593B2 (en) 1995-01-05
CA2086097C (en) 2001-06-12
PT98119A (pt) 1992-04-30
BR9106601A (pt) 1993-04-20
PT98119B (pt) 1998-12-31
ES2104712T3 (es) 1997-10-16
AU8286191A (en) 1992-01-23
DE69127445D1 (de) 1997-10-02
WO1992000101A1 (en) 1992-01-09
CA2086097A1 (en) 1991-12-28
CN1060027A (zh) 1992-04-08
NZ238731A (en) 1996-02-27
JPH05507498A (ja) 1993-10-28
EP0536302B1 (de) 1997-08-27
JPH0832639B2 (ja) 1996-03-29
KR100218138B1 (en) 1999-09-01
EP0536302A1 (de) 1993-04-14
DK0536302T3 (da) 1997-09-29
EP0536302A4 (en) 1993-08-04
IL98655A0 (en) 1992-07-15
GR3025341T3 (en) 1998-02-27
IE912257A1 (en) 1992-01-01
DE69127445T2 (de) 1998-03-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee