ATE157867T1 - Geschmacksmaskierende zusammensetzungen von ranitidin - Google Patents
Geschmacksmaskierende zusammensetzungen von ranitidinInfo
- Publication number
- ATE157867T1 ATE157867T1 AT93923462T AT93923462T ATE157867T1 AT E157867 T1 ATE157867 T1 AT E157867T1 AT 93923462 T AT93923462 T AT 93923462T AT 93923462 T AT93923462 T AT 93923462T AT E157867 T1 ATE157867 T1 AT E157867T1
- Authority
- AT
- Austria
- Prior art keywords
- ranitidine
- pct
- date apr
- flavor
- lipid
- Prior art date
Links
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical group [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 title abstract 5
- 229960000620 ranitidine Drugs 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002687 nonaqueous vehicle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929221760A GB9221760D0 (en) | 1992-10-16 | 1992-10-16 | Medicaments |
| GB929221800A GB9221800D0 (en) | 1992-10-16 | 1992-10-16 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE157867T1 true ATE157867T1 (de) | 1997-09-15 |
Family
ID=26301808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93923462T ATE157867T1 (de) | 1992-10-16 | 1993-10-14 | Geschmacksmaskierende zusammensetzungen von ranitidin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5635200A (de) |
| EP (1) | EP0664701B1 (de) |
| JP (1) | JPH08510989A (de) |
| CN (1) | CN1052877C (de) |
| AT (1) | ATE157867T1 (de) |
| AU (1) | AU669952B2 (de) |
| CA (1) | CA2146999A1 (de) |
| DE (1) | DE69313865T2 (de) |
| ES (1) | ES2107685T3 (de) |
| IL (1) | IL107303A (de) |
| MX (1) | MX9306393A (de) |
| WO (1) | WO1994008576A1 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995000125A1 (en) * | 1993-06-18 | 1995-01-05 | Smithkline Beecham Corporation | Soft-shelled gelatin encapsulated particles |
| MY111346A (en) * | 1993-07-09 | 1999-11-30 | Smithkline Beecham Corp | Soft-shelled gelatin encapsulated particles |
| US5622980A (en) * | 1993-08-17 | 1997-04-22 | Applied Analytical Industries, Inc. | Oral compositions of H2-antagonists |
| DK171127B1 (da) * | 1994-04-22 | 1996-06-24 | Gea Farmaceutisk Fabrik As | Ranitidintablet med et hydroxypropylmethylcelluloseholdigt overtræk samt fremgangsmåde til at tilvejebringe dette overtræk |
| US5538737A (en) * | 1994-11-30 | 1996-07-23 | Applied Analytical Industries, Inc. | Oral compositions of H2 -antagonists |
| BR9608962A (pt) | 1995-06-09 | 1999-06-29 | R P Scheer Corp | Suspensão de um agente ativo apropriado e cápsula de gelatina |
| US5706830A (en) * | 1996-05-06 | 1998-01-13 | South Alabama Medical Science Foundation | Liquid ventilator system and use thereof |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| WO1998014179A1 (en) * | 1996-10-01 | 1998-04-09 | Cima Labs Inc. | Taste-masked microcapsule compositions and methods of manufacture |
| US6242019B1 (en) | 1997-08-14 | 2001-06-05 | Warner-Lambert Company | Taste modified hard confectionery compositions containing functional ingredients |
| NZ503086A (en) | 1997-08-29 | 2002-03-01 | Upjohn Co | An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes |
| GB9806477D0 (en) * | 1998-03-26 | 1998-05-27 | Glaxo Group Ltd | Improved crystals |
| GB9819272D0 (en) * | 1998-09-03 | 1998-10-28 | Andaris Ltd | Microparticles |
| JP2002179560A (ja) * | 1999-02-26 | 2002-06-26 | Shionogi & Co Ltd | 服用性を改良した咀嚼型ソフトカプセル剤およびその製法 |
| EP1163901B1 (de) | 1999-02-26 | 2008-09-10 | Shionogi & Co., Ltd. | Kaubare weichkapseln mit verbesserten verabreichungseigenschaften sowie verfahren zu deren herstellung |
| PT1165042E (pt) | 1999-04-06 | 2005-06-30 | Ethypharm Sa | Suspensao farmaceutica bebivel de ibuprofeno |
| US6541025B1 (en) * | 1999-12-30 | 2003-04-01 | Shear/Kershman Laboratories, Inc. | Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
| FR2821747B1 (fr) * | 2001-03-09 | 2004-07-02 | Ethypharm Lab Prod Ethiques | Suspension de telithromycine a gout masque |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| HRP20020124A2 (en) * | 2002-02-11 | 2003-10-31 | Pliva D D | Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping |
| SE0200475D0 (sv) * | 2002-02-15 | 2002-02-15 | Ltp Lipid Technologies Provide | Oral farmaceutisk beredning |
| AU2003209673B2 (en) * | 2002-03-08 | 2007-10-18 | M/S. Ind-Swift Limited | Tasteless directly compressible fast-dissolving complexes and pharmaceutical formulations thereof |
| US20040096498A1 (en) * | 2002-04-29 | 2004-05-20 | Alvin Kershman | Oral pharmaceutical delivery system with improved sustained release |
| WO2004016247A1 (en) * | 2002-08-14 | 2004-02-26 | E.I. Du Pont De Nemours And Company | Process for coating a pharmaceutical particle |
| FR2848855B1 (fr) * | 2002-12-23 | 2005-02-11 | Aventis Pharma Sa | Compositions pour administration orale de principes actifs necessitant un masquage du gout |
| US20040146553A1 (en) | 2002-12-23 | 2004-07-29 | Aventis Pharma S.A. | Compositions for oral administration of active principles requiring masking of taste |
| US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| US20060233873A1 (en) * | 2003-01-24 | 2006-10-19 | Julien Meissonnier | Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same |
| FR2850275B1 (fr) * | 2003-01-24 | 2005-04-08 | Scherer Technologies Inc R P | Capsules molles a macher contenant une substance active a gout masque |
| US20040185170A1 (en) * | 2003-03-21 | 2004-09-23 | Shubha Chungi | Method for coating drug-containing particles and formulations and dosage units formed therefrom |
| WO2004091582A1 (en) * | 2003-04-17 | 2004-10-28 | Ipca Laboratories Limited | Pharmaceutical preparations on the basis of moisture-protected granules and a process for producing them |
| US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
| ITMI20041820A1 (it) * | 2004-09-24 | 2004-12-24 | Ascor Chimici Srl | Composizione in micro-pellets a rilascio controllato di sostanze fisiologicamente attive, procedimento di preparazione e relativo impiego nel settore zootecnico. |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| WO2006047493A2 (en) | 2004-10-21 | 2006-05-04 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| US20060100271A1 (en) * | 2004-11-08 | 2006-05-11 | Keith Whitehead | Stabilized aqueous ranitidine compositions |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| SG10201407965XA (en) | 2009-12-02 | 2015-02-27 | Aptalis Pharma Ltd | Fexofenadine microcapsules and compositions containing them |
| JP5609105B2 (ja) * | 2009-12-24 | 2014-10-22 | ライオン株式会社 | ラニチジン含有被覆粒子及びその製造方法 |
| FR2959130A1 (fr) * | 2010-04-21 | 2011-10-28 | Sanofi Aventis | Procede de preparation de compositions pharmaceutiques destinees a l'administration par voie orale comprenant un ou plusieurs principes actifs et les compositions les comprenant. |
| US20160000714A1 (en) | 2013-03-06 | 2016-01-07 | Capsugel Belgium Nv | Curcumin solid lipid particles and methods for their preparation and use |
| EP3154529B1 (de) * | 2014-06-10 | 2020-07-08 | Capsugel Belgium NV | Orale, schnell-zerfallende tablette mit festen lipidpartikeln und verfahren zu deren herstellung und verwendung |
| WO2016087261A1 (en) | 2014-12-04 | 2016-06-09 | Capsugel Belgium N.V. | Lipid multiparticulate formulations |
| CN105030694A (zh) * | 2015-08-04 | 2015-11-11 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗胃溃疡的药物盐酸雷尼替丁组合物干混悬剂 |
| CN112020350A (zh) | 2018-04-27 | 2020-12-01 | 强生消费者公司 | 液体口服药物剂型 |
| US20240226038A9 (en) * | 2022-10-19 | 2024-07-11 | Genexa Inc. | Solid pharmaceutical tablet |
| WO2025253307A1 (en) * | 2024-06-04 | 2025-12-11 | Kenvue Brands Llc | Softgel capsule comprising a h2 receptor antagonist |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE74009T1 (de) * | 1986-08-11 | 1992-04-15 | American Cyanamid Co | Zusammensetzungen zur parenteralen verabreichung und deren verwendung. |
| SE8605515D0 (sv) * | 1986-12-22 | 1986-12-22 | Astra Laekemedel Ab | A liquid dosage form for oral administration of a pharmaceutically active substance |
| NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
| GB8730011D0 (en) * | 1987-12-23 | 1988-02-03 | Smithkline Dauelsberg | Pharmaceutical compositions |
| US5219563A (en) * | 1988-05-11 | 1993-06-15 | Glaxo Group Limited | Drug adsorbates |
| IL90245A (en) * | 1988-05-11 | 1994-04-12 | Glaxo Group Ltd | Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it |
| GB8904182D0 (en) * | 1989-02-23 | 1989-04-05 | Glaxo Canada | Pharmaceutical compositions |
| US5275823A (en) * | 1989-04-27 | 1994-01-04 | Smith Kline & French Laboratories Ltd. | Pharmaceutical compositions |
| US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
| EP0421581A1 (de) * | 1989-10-03 | 1991-04-10 | Warner-Lambert Company | Kaubare sprühgetrocknete spheroide Mikrokapseln, wachsüberzogene Mikrokapseln und Verfahren zu ihrer Herstellung |
| US5290569A (en) * | 1990-04-12 | 1994-03-01 | Shionogi & Co., Ltd. | Coated composition and its preparation process |
| US5075114A (en) * | 1990-05-23 | 1991-12-24 | Mcneil-Ppc, Inc. | Taste masking and sustained release coatings for pharmaceuticals |
| US5260072A (en) * | 1990-08-30 | 1993-11-09 | Mcneil-Ppc, Inc. | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
| WO1992004893A1 (en) * | 1990-09-13 | 1992-04-02 | Smithkline Beecham Corporation | Non-aqueous liquid oral suspensions |
| FI922107A0 (fi) * | 1991-05-10 | 1992-05-08 | Faulding F H & Co Ltd | Mikrokapselkomposition och foerfarande. |
| ES2202302T3 (es) * | 1991-05-28 | 2004-04-01 | Mcneil-Ppc, Inc. | Composicion masticable que libera un farmaco. |
| US5380535A (en) * | 1991-05-28 | 1995-01-10 | Geyer; Robert P. | Chewable drug-delivery compositions and methods for preparing the same |
| US5429825A (en) * | 1992-06-26 | 1995-07-04 | Mcneil-Ppc, Inc. | Rotomelt granulation |
-
1993
- 1993-10-14 AU AU53336/94A patent/AU669952B2/en not_active Ceased
- 1993-10-14 US US08/411,828 patent/US5635200A/en not_active Expired - Fee Related
- 1993-10-14 CA CA002146999A patent/CA2146999A1/en not_active Abandoned
- 1993-10-14 AT AT93923462T patent/ATE157867T1/de not_active IP Right Cessation
- 1993-10-14 ES ES93923462T patent/ES2107685T3/es not_active Expired - Lifetime
- 1993-10-14 DE DE69313865T patent/DE69313865T2/de not_active Expired - Fee Related
- 1993-10-14 MX MX9306393A patent/MX9306393A/es not_active IP Right Cessation
- 1993-10-14 EP EP93923462A patent/EP0664701B1/de not_active Expired - Lifetime
- 1993-10-14 JP JP6509630A patent/JPH08510989A/ja active Pending
- 1993-10-14 WO PCT/EP1993/002832 patent/WO1994008576A1/en not_active Ceased
- 1993-10-15 IL IL107303A patent/IL107303A/en not_active IP Right Cessation
- 1993-10-15 CN CN93115015A patent/CN1052877C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1052877C (zh) | 2000-05-31 |
| DE69313865T2 (de) | 1998-02-12 |
| DE69313865D1 (de) | 1997-10-16 |
| AU5333694A (en) | 1994-05-09 |
| IL107303A0 (en) | 1994-01-25 |
| JPH08510989A (ja) | 1996-11-19 |
| MX9306393A (es) | 1994-04-29 |
| EP0664701A1 (de) | 1995-08-02 |
| CN1092648A (zh) | 1994-09-28 |
| ES2107685T3 (es) | 1997-12-01 |
| US5635200A (en) | 1997-06-03 |
| WO1994008576A1 (en) | 1994-04-28 |
| IL107303A (en) | 1998-02-08 |
| EP0664701B1 (de) | 1997-09-10 |
| CA2146999A1 (en) | 1994-04-28 |
| AU669952B2 (en) | 1996-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |