ATE159296T1 - Promotor-regulator und das für indikator-protein kodierende gen enthaltendes chimäres gen - Google Patents
Promotor-regulator und das für indikator-protein kodierende gen enthaltendes chimäres genInfo
- Publication number
- ATE159296T1 ATE159296T1 AT92109881T AT92109881T ATE159296T1 AT E159296 T1 ATE159296 T1 AT E159296T1 AT 92109881 T AT92109881 T AT 92109881T AT 92109881 T AT92109881 T AT 92109881T AT E159296 T1 ATE159296 T1 AT E159296T1
- Authority
- AT
- Austria
- Prior art keywords
- gene
- promotor
- regulator
- indicator protein
- chimeric gene
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108010053187 Diphtheria Toxin Proteins 0.000 abstract 1
- 102000016607 Diphtheria Toxin Human genes 0.000 abstract 1
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919113097A GB9113097D0 (en) | 1991-06-18 | 1991-06-18 | Chimeric gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE159296T1 true ATE159296T1 (de) | 1997-11-15 |
Family
ID=10696850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92109881T ATE159296T1 (de) | 1991-06-18 | 1992-06-12 | Promotor-regulator und das für indikator-protein kodierende gen enthaltendes chimäres gen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0519336B1 (de) |
| JP (1) | JP3372267B2 (de) |
| AT (1) | ATE159296T1 (de) |
| DE (1) | DE69222690T2 (de) |
| ES (1) | ES2108061T3 (de) |
| GB (1) | GB9113097D0 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464758A (en) * | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| GB9405350D0 (en) * | 1994-03-18 | 1994-05-04 | Sandoz Ltd | Organic compounds |
| US5851796A (en) * | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
| AU2814897A (en) * | 1996-04-25 | 1997-11-12 | T Cell Sciences, Inc. | Method of isolating regulators of t cell activation |
| US6566089B1 (en) * | 1996-09-04 | 2003-05-20 | Tularik Inc. | Cell-based drug screens for regulators of gene expression |
| EP1157126A4 (de) * | 1999-02-24 | 2005-03-02 | Gen Hospital Corp | Verfahren zum klonen von zwischenprodukten für signaltransduktion |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03502882A (ja) * | 1987-12-15 | 1991-07-04 | ザ トラスティーズ オブ プリンストン ユニヴァーシティ | 変異原物質および発癌物質に関するトランスジェニック試験システム |
| GB8905394D0 (en) * | 1989-03-09 | 1989-04-19 | Delta Biotechnology Ltd | Detection of certain molecules |
| AU660405B2 (en) * | 1989-07-18 | 1995-06-29 | Osi Pharmaceuticals, Inc. | Method of transcriptionally modulating gene expression and of discovering chemicals capable of functioning as gene expression modulators |
| WO1992014839A1 (en) * | 1991-02-14 | 1992-09-03 | Imperial Cancer Research Technology Limited | Test method |
-
1991
- 1991-06-18 GB GB919113097A patent/GB9113097D0/en active Pending
-
1992
- 1992-06-12 DE DE69222690T patent/DE69222690T2/de not_active Expired - Lifetime
- 1992-06-12 ES ES92109881T patent/ES2108061T3/es not_active Expired - Lifetime
- 1992-06-12 EP EP92109881A patent/EP0519336B1/de not_active Expired - Lifetime
- 1992-06-12 AT AT92109881T patent/ATE159296T1/de active
- 1992-06-17 JP JP15788492A patent/JP3372267B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05252955A (ja) | 1993-10-05 |
| DE69222690D1 (de) | 1997-11-20 |
| EP0519336A3 (en) | 1993-04-28 |
| DE69222690T2 (de) | 1998-02-26 |
| JP3372267B2 (ja) | 2003-01-27 |
| GB9113097D0 (en) | 1991-08-07 |
| ES2108061T3 (es) | 1997-12-16 |
| EP0519336B1 (de) | 1997-10-15 |
| EP0519336A2 (de) | 1992-12-23 |
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