ATE159717T1 - Neue kristalline form einer dem vitamin d analogen verbindung - Google Patents

Neue kristalline form einer dem vitamin d analogen verbindung

Info

Publication number: ATE159717T1
Authority: AT; Austria
Prior art keywords: crystalline form; vitamin; new crystalline; analogue compound; calcipotriol
Prior art date: 1993-01-15

Application number

AT94904583T

Other languages

English (en)

Inventor

Erik Torngaard Hansen

Andersen Niels Smidt Rastrup

Lene Hoffmeyer Ringborg

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-15

Filing date

1994-01-07

Publication date

1997-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10728784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE159717(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-01-07 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1997-11-15 Application granted granted Critical

1997-11-15 Publication of ATE159717T1 publication Critical patent/ATE159717T1/de

Links

150000001875 compounds Chemical class 0.000 title 1
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
LWQQLNNNIPYSNX-UROSTWAQSA-N calcipotriol Chemical compound C1([C@H](O)/C=C/[C@@H](C)[C@@H]2[C@]3(CCCC(/[C@@H]3CC2)=C\C=C\2C([C@@H](O)C[C@H](O)C/2)=C)C)CC1 LWQQLNNNIPYSNX-UROSTWAQSA-N 0.000 abstract 1
229960002882 calcipotriol Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/02—Apparatus characterised by being constructed of material selected for its chemically-resistant properties
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
- C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
- C07C5/321—Catalytic processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
- C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
- C07C5/327—Formation of non-aromatic carbon-to-carbon double bonds only
- C07C5/333—Catalytic processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
- C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
- C07C5/327—Formation of non-aromatic carbon-to-carbon double bonds only
- C07C5/333—Catalytic processes
- C07C5/3335—Catalytic processes with metals
- C07C5/3337—Catalytic processes with metals of the platinum group
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/02—Apparatus characterised by their chemically-resistant properties
- B01J2219/0204—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/02—Apparatus characterised by their chemically-resistant properties
- B01J2219/0204—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
- B01J2219/0236—Metal based
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/02—Apparatus characterised by their chemically-resistant properties
- B01J2219/025—Apparatus characterised by their chemically-resistant properties characterised by the construction materials of the reactor vessel proper
- B01J2219/0277—Metal based
- B01J2219/0286—Steel
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
- C07C2523/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
- C07C2523/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
- C07C2523/42—Platinum

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT94904583T 1993-01-15 1994-01-07 Neue kristalline form einer dem vitamin d analogen verbindung ATE159717T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB939300763A GB9300763D0 (en)	1993-01-15	1993-01-15	Chemical compound

Publications (1)

Publication Number	Publication Date
ATE159717T1 true ATE159717T1 (de)	1997-11-15

Family

ID=10728784

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94904583T ATE159717T1 (de)	1993-01-15	1994-01-07	Neue kristalline form einer dem vitamin d analogen verbindung

Country Status (17)

Country	Link
US (2)	USRE39706E1 (de)
EP (1)	EP0679154B1 (de)
JP (1)	JP3729847B2 (de)
KR (1)	KR100309751B1 (de)
CN (1)	CN1040746C (de)
AT (1)	ATE159717T1 (de)
AU (1)	AU663249B2 (de)
CA (1)	CA2151730C (de)
DE (1)	DE69406529T2 (de)
DK (1)	DK0679154T3 (de)
ES (1)	ES2111287T3 (de)
FI (1)	FI108638B (de)
GB (1)	GB9300763D0 (de)
GR (1)	GR3025668T3 (de)
NZ (1)	NZ259679A (de)
RU (1)	RU2128646C1 (de)
WO (1)	WO1994015912A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU710931B2 (en) *	1996-02-28	1999-09-30	Sumitomo Pharmaceuticals Company, Limited	Crystalline vitamin D derivative
US8263580B2 (en)	1998-09-11	2012-09-11	Stiefel Research Australia Pty Ltd	Vitamin formulation
ES2388425T5 (es) *	1999-04-23	2020-02-12	Leo Pharma As	Composición farmacéutica no acuosa para uso dérmico para tratar la psoriasis que comprende una vitamina D, un corticoesteroide y un componente disolvente
US20090098065A1 (en) *	2000-01-11	2009-04-16	Avikam Harel	Composition and methods for the treatment of skin disorders
EP1458678A1 (de) *	2002-11-18	2004-09-22	Teva Pharmaceutical Industries Limited	Kristallisationsverfahren zur reinigung von calcipotriene
MY139521A (en) *	2004-03-18	2009-10-30	Leo Pharma As	Stereoselective synthesis of vitamin d analogues
ATE390411T1 (de) *	2004-03-18	2008-04-15	Leo Pharma As	Stereoselektive synthese von vitamin-d-analoga
FR2871696B1 (fr) *	2004-06-17	2006-11-10	Galderma Sa	Composition topique pour le traitement du psoriasis
TWI318203B (en) *	2004-09-01	2009-12-11	Leo Pharma As	Epimerization of allylic alcohols
EP1917072B1 (de)	2005-06-01	2013-02-27	Stiefel Research Australia Pty Ltd	Vitaminformulierung
ATE489380T1 (de) *	2006-02-10	2010-12-15	Amgen Inc	Hydratformen von amg706
ES2406735T3 (es) *	2006-03-17	2013-06-07	Leo Pharma A/S	Isomerización de compuestos intermedios farmacéuticos
KR20110113664A (ko) *	2006-08-29	2011-10-17	테바 파마슈티컬 인더스트리즈 리미티드	비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
US20100056644A1 (en) *	2006-11-29	2010-03-04	Nilendu Sen	Pharmaceutical compositions containing anhydrous calcipotriene
ES2272198B1 (es) *	2006-12-28	2008-06-01	Laboratorios Viñas S.A.	Procedimiento para la obtencion de hidrato de calcipotriol.
EP1970048A1 (de) *	2007-03-15	2008-09-17	Drug Delivery Solutions Limited	Polyaphron topische Zusammensetzung mit Vitamin D
US10265265B2 (en) *	2007-03-15	2019-04-23	Drug Delivery Solutions Limited	Topical composition
EP2008651A1 (de)	2007-06-26	2008-12-31	Drug Delivery Solutions Limited	Biologisch erodierbares Patch
KR20110010753A (ko) *	2008-05-08	2011-02-07	유나이티드 세러퓨틱스 코오포레이션	트레프로스티닐 일수화물
US20120184514A1 (en) *	2009-07-01	2012-07-19	Vitamin Derivatives Inc.	Vitamin d compounds and methods for preparing same
US9254296B2 (en)	2009-12-22	2016-02-09	Leo Pharma A/S	Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture
US20120322776A1 (en)	2009-12-22	2012-12-20	Leo Pharma A/S	Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
BR112012015449B1 (pt) *	2009-12-22	2021-09-28	Leo Pharma A/S	Suspensão de monoidrato de calcipotriol, e, processo para preparar nanocristais de monoidrato de calcipotriol
AU2009357263B2 (en) *	2009-12-22	2015-04-09	Leo Pharma A/S	Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture
CN102770121B (zh)	2009-12-22	2014-10-15	利奥制药有限公司	包含溶剂混合物和维生素d衍生物或类似物的药物组合物
KR101619077B1 (ko)	2010-06-11	2016-05-10	레오 파마 에이/에스	비타민 ｄ 유사체 및 코르티코스테로이드를 포함하는 약제학적 분무 조성물
BR112013023458B1 (pt)	2011-03-14	2020-04-07	Drug Delivery Solutions Ltd	composição oftálmica, e, método para fabricar a composição oftálmica
KR20140031227A (ko)	2011-03-24	2014-03-12	레오 파마 에이/에스	지질 나노입자들 및 코르티코스테로이드 또는 비타민 ｄ 유도체를 포함하는 조성물
JP5652723B2 (ja) *	2012-08-17	2015-01-14	フォーモサ・ラボラトリーズ・インコーポレーテッド	マキサカルシトールの新しい結晶形態
CN103724162A (zh) *	2014-01-07	2014-04-16	成都医路康医学技术服务有限公司	一种银屑病治疗药物卡泊三醇溶剂化物的制备方法
MA41818A (fr)	2015-03-27	2018-01-30	Leo Pharma As	Timbre à micro-aiguilles pour administration d'un principe actif à la peau
EP3542788A1 (de)	2018-03-19	2019-09-25	MC2 Therapeutics Limited	Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2457282A1 (fr) *	1979-05-23	1980-12-19	Roussel Uclaf	Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
JPS59104358A (ja)	1982-12-03	1984-06-16	Teijin Ltd	１α，２４−ジヒドロキシコレカルシフエロ−ルの一水塩及びその製造法
DE3666587D1 (en) *	1985-08-02	1989-11-30	Leo Pharm Prod Ltd	Novel vitamin d analogues
GB9004544D0 (en) *	1990-03-01	1990-04-25	Leo Pharm Prod Ltd	Novel treatment ii

1993
- 1993-01-15 US US10/986,575 patent/USRE39706E1/en not_active Expired - Lifetime
- 1993-01-15 GB GB939300763A patent/GB9300763D0/en active Pending
- 1993-01-15 US US08/491,892 patent/US5763426A/en not_active Ceased
1994
- 1994-01-07 AU AU58573/94A patent/AU663249B2/en not_active Expired
- 1994-01-07 JP JP51560694A patent/JP3729847B2/ja not_active Expired - Lifetime
- 1994-01-07 DK DK94904583.5T patent/DK0679154T3/da active
- 1994-01-07 RU RU95116650A patent/RU2128646C1/ru active
- 1994-01-07 ES ES94904583T patent/ES2111287T3/es not_active Expired - Lifetime
- 1994-01-07 EP EP94904583A patent/EP0679154B1/de not_active Expired - Lifetime
- 1994-01-07 NZ NZ259679A patent/NZ259679A/en not_active IP Right Cessation
- 1994-01-07 DE DE69406529T patent/DE69406529T2/de not_active Expired - Lifetime
- 1994-01-07 CN CN94190817A patent/CN1040746C/zh not_active Expired - Lifetime
- 1994-01-07 WO PCT/DK1994/000011 patent/WO1994015912A1/en not_active Ceased
- 1994-01-07 CA CA002151730A patent/CA2151730C/en not_active Expired - Lifetime
- 1994-01-07 AT AT94904583T patent/ATE159717T1/de active
- 1994-01-07 KR KR1019950702271A patent/KR100309751B1/ko not_active Expired - Lifetime
1995
- 1995-06-07 FI FI952797A patent/FI108638B/fi not_active IP Right Cessation
1997
- 1997-12-16 GR GR970403317T patent/GR3025668T3/el unknown

Also Published As

Publication number	Publication date
USRE39706E1 (en)	2007-06-26
AU5857394A (en)	1994-08-15
DE69406529T2 (de)	1998-05-28
RU95116650A (ru)	1997-06-10
JPH08505612A (ja)	1996-06-18
ES2111287T3 (es)	1998-03-01
FI108638B (fi)	2002-02-28
FI952797L (fi)	1995-06-07
GR3025668T3 (en)	1998-03-31
RU2128646C1 (ru)	1999-04-10
NZ259679A (en)	1996-11-26
EP0679154B1 (de)	1997-10-29
CA2151730C (en)	2005-01-04
GB9300763D0 (en)	1993-03-03
CN1040746C (zh)	1998-11-18
EP0679154A1 (de)	1995-11-02
CA2151730A1 (en)	1994-07-21
JP3729847B2 (ja)	2005-12-21
WO1994015912A1 (en)	1994-07-21
KR100309751B1 (ko)	2002-11-08
DE69406529D1 (de)	1997-12-04
DK0679154T3 (da)	1998-03-30
CN1115979A (zh)	1996-01-31
US5763426A (en)	1998-06-09
KR950704249A (ko)	1995-11-17
FI952797A0 (fi)	1995-06-07
AU663249B2 (en)	1995-09-28

Legal Events

Date	Code	Title	Description
1998-08-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE69406529D1 (de)	1997-12-04	Neue kristalline form einer dem vitamin d analogen verbindung
MX9304581A (es)	1994-07-29	Desoxitaxoles y composiciones farmaceuticas que los contienen
TW269682B (de)	1996-02-01
NL1002835A1 (nl)	1996-10-14	Synergistisch stabilisatormengsel.
AU3440393A (en)	1993-08-03	Colorless detergent compositions with enhanced stability
FI941388L (fi)	1994-03-25	Paineistetut aerosolikoostumukset
ES2098921T3 (es)	1997-05-01	Composiciones de cetoconazol de uso topico.
MX9301129A (es)	1994-07-29	Nuevas ciclosporinas y composiciones farmaceuticas que las contienen.
TW225534B (de)	1994-06-21
PL309282A1 (en)	1995-10-02	Application of 2-amino-6-n-propyl-amino- 4,5,6,7-tetrahydrobenzothiasole (pramipexol) as an antidepressant
DK0655065T3 (de)	1997-02-24
AU2358292A (en)	1993-04-08	Amine-boron adducts as reduced odor catalyst compositions for the production of polyurethanes
IL106748A0 (en)	1993-12-08	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
ZA9410023B (en)	1995-09-29	Herbicides
MX9303970A (es)	1994-04-29	COMPUESTOS ESTEROIDALES DE ANILLO A DE 17Ó Y 17ß-ALQUILCETONA-3-CARBOXIAROMATICO.
GR1002385B (el)	1996-07-03	Καθαρη μορφη στρεπτογραμινων, παρασκευη αυτης και φαρμακευτικες συνθεσεις που την περιεχουν.
MX9302878A (es)	1994-07-29	Procedimiento para la preparacion de un diaminodiol substituido.
ITTO940823A0 (it)	1994-10-17	Composizione per regolare la crescita di insetti.
DE69614552D1 (de)	2001-09-20	MODIFIZIERTE ALPHA-D-GLCP-(1,2)-ALPHA-D-Glcp-(1,3)-ALPHA-D-Glcp-ANALOGE
IT1243440B (it)	1994-06-10	Composizioni di polifenilenossido o di miscele di polifenilenossido stabilizzate con composti contenenti un triplo legame acetilenico.
IL101743A0 (en)	1992-12-30	2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors
ES2105290T3 (es)	1997-10-16	Composicion herbicida.
FI924088L (fi)	1992-09-11	Anvaendning av prostaglandin f3a som oegontryck saenkande medel
MY108690A (en)	1996-10-31	Mildewproofing agent for timber
UA43324C2 (uk)	2001-12-17	Протитромботичний засіб