ATE160223T1 - Kombinatorische bibliotheken und verfahren zu ihrer verwendung - Google Patents
Kombinatorische bibliotheken und verfahren zu ihrer verwendungInfo
- Publication number
- ATE160223T1 ATE160223T1 AT94925706T AT94925706T ATE160223T1 AT E160223 T1 ATE160223 T1 AT E160223T1 AT 94925706 T AT94925706 T AT 94925706T AT 94925706 T AT94925706 T AT 94925706T AT E160223 T1 ATE160223 T1 AT E160223T1
- Authority
- AT
- Austria
- Prior art keywords
- different
- subunit
- polysubunits
- methods
- subunits
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000010276 construction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00592—Split-and-pool, mix-and-divide processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16896693A | 1993-12-15 | 1993-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE160223T1 true ATE160223T1 (de) | 1997-11-15 |
Family
ID=22613731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925706T ATE160223T1 (de) | 1993-12-15 | 1994-07-26 | Kombinatorische bibliotheken und verfahren zu ihrer verwendung |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0734530B1 (de) |
| JP (1) | JPH09506611A (de) |
| AT (1) | ATE160223T1 (de) |
| AU (1) | AU7552394A (de) |
| DE (1) | DE69406806D1 (de) |
| SG (1) | SG48166A1 (de) |
| WO (1) | WO1995016918A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69430727T2 (de) | 1993-07-26 | 2003-03-06 | Innovasive Devices, Inc. | Greifereinrichtung für nahtmaterial |
| US7034110B2 (en) | 1994-01-05 | 2006-04-25 | Arqule, Inc. | Method of identifying chemical compounds having selected properties for a particular application |
| US5712171A (en) | 1995-01-20 | 1998-01-27 | Arqule, Inc. | Method of generating a plurality of chemical compounds in a spatially arranged array |
| EP0906334A1 (de) | 1996-04-24 | 1999-04-07 | Peptide Therapeutics Limited | Sich selbst entschlüsselnde kombinatorische substanz-bibliotheken |
| IL140001A0 (en) | 1998-06-24 | 2002-02-10 | Aventis Pharm Prod Inc | Flourophenyl resin compounds |
| US7060431B2 (en) | 1998-06-24 | 2006-06-13 | Illumina, Inc. | Method of making and decoding of array sensors with microspheres |
| US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
| JP4813660B2 (ja) | 1998-11-27 | 2011-11-09 | ダーウィン ディスカバリー リミテッド | 骨鉱化作用を増加するための組成物および方法 |
| US6864235B1 (en) | 1999-04-01 | 2005-03-08 | Eva A. Turley | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US6911429B2 (en) | 1999-04-01 | 2005-06-28 | Transition Therapeutics Inc. | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| ATE542916T1 (de) | 1999-08-18 | 2012-02-15 | Illumina Inc | Methoden zur erzeugung von oligonukleotidlösungen |
| AU3806701A (en) | 2000-02-07 | 2001-08-14 | Illumina Inc | Nucleic acid detection methods using universal priming |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| AU2001238068A1 (en) | 2000-02-07 | 2001-08-14 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| ATE412774T1 (de) | 2000-02-16 | 2008-11-15 | Illumina Inc | Parallele genotypisierung mehrerer patientenproben |
| ATE405586T1 (de) | 2001-05-08 | 2008-09-15 | Darwin Molecular Corp | Verfahren zur regulierung der immunfunktion in primaten unter verwendung des foxp3-proteins |
| EP2258724A1 (de) | 2002-11-21 | 2010-12-08 | Celltech R & D, Inc. | Modulierung von Immunantworten mittels multimeriserter Anti-CD83 Antikörper |
| WO2008067196A2 (en) | 2006-11-16 | 2008-06-05 | The Regents Of The University Of California | Methods for identifying inhibitors of solute transporters |
| WO2009079373A2 (en) | 2007-12-14 | 2009-06-25 | The Regents Of The University Of California | Inhibitors of calcium-activated chloride channels |
| TWI492951B (zh) | 2007-12-31 | 2015-07-21 | Baxter Int | 表現人類凝血因子的基因轉殖非人類動物及其用途 |
| AU2012328457A1 (en) | 2011-10-28 | 2014-04-24 | Presage Biosciences, Inc. | Methods for drug delivery |
| CA3217862A1 (en) | 2021-05-05 | 2022-11-10 | Radius Pharmaceuticals, Inc. | Animal model having homologous recombination of mouse pth1 receptor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5650489A (en) * | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| EP0558671B1 (de) * | 1990-11-21 | 1999-01-27 | Iterex Pharmaceuticals Ltd. Partnership | Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen |
| US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
-
1994
- 1994-07-26 AT AT94925706T patent/ATE160223T1/de not_active IP Right Cessation
- 1994-07-26 EP EP94925706A patent/EP0734530B1/de not_active Expired - Lifetime
- 1994-07-26 JP JP7516736A patent/JPH09506611A/ja not_active Ceased
- 1994-07-26 SG SG1996007530A patent/SG48166A1/en unknown
- 1994-07-26 WO PCT/US1994/008542 patent/WO1995016918A1/en not_active Ceased
- 1994-07-26 DE DE69406806T patent/DE69406806D1/de not_active Expired - Lifetime
- 1994-07-26 AU AU75523/94A patent/AU7552394A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09506611A (ja) | 1997-06-30 |
| WO1995016918A1 (en) | 1995-06-22 |
| EP0734530B1 (de) | 1997-11-12 |
| DE69406806D1 (de) | 1997-12-18 |
| SG48166A1 (en) | 1998-04-17 |
| EP0734530A1 (de) | 1996-10-02 |
| AU7552394A (en) | 1995-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |