ATE160676T1 - Pulverförmiges mannitol mit verringerter versprödung und seine herstellung - Google Patents

Pulverförmiges mannitol mit verringerter versprödung und seine herstellung

Info

Publication number
ATE160676T1
ATE160676T1 AT94402134T AT94402134T ATE160676T1 AT E160676 T1 ATE160676 T1 AT E160676T1 AT 94402134 T AT94402134 T AT 94402134T AT 94402134 T AT94402134 T AT 94402134T AT E160676 T1 ATE160676 T1 AT E160676T1
Authority
AT
Austria
Prior art keywords
powdered mannitol
production
microns
particle size
reduced brittleness
Prior art date
Application number
AT94402134T
Other languages
English (en)
Inventor
Michel Serpelloni
Jean-Philippe Boonaert
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9451298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE160676(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roquette Freres filed Critical Roquette Freres
Application granted granted Critical
Publication of ATE160676T1 publication Critical patent/ATE160676T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/34—Sugar alcohols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Peptides Or Proteins (AREA)
AT94402134T 1993-09-28 1994-09-26 Pulverförmiges mannitol mit verringerter versprödung und seine herstellung ATE160676T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9311513A FR2710637B1 (fr) 1993-09-28 1993-09-28 Mannitol pulvérulent de friabilité modérée et son procédé de préparation.

Publications (1)

Publication Number Publication Date
ATE160676T1 true ATE160676T1 (de) 1997-12-15

Family

ID=9451298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94402134T ATE160676T1 (de) 1993-09-28 1994-09-26 Pulverförmiges mannitol mit verringerter versprödung und seine herstellung

Country Status (16)

Country Link
US (1) US5573777A (de)
EP (1) EP0645096B1 (de)
JP (1) JP3492428B2 (de)
KR (1) KR100353433B1 (de)
CN (1) CN1046622C (de)
AT (1) ATE160676T1 (de)
AU (1) AU675732B2 (de)
CA (1) CA2133012C (de)
DE (1) DE69407123T2 (de)
DK (1) DK0645096T3 (de)
ES (1) ES2109635T3 (de)
FI (1) FI112356B (de)
FR (1) FR2710637B1 (de)
GR (1) GR3025720T3 (de)
HU (1) HU217453B (de)
NO (1) NO302356B1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997038960A1 (en) 1996-04-16 1997-10-23 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
DE19615418A1 (de) * 1996-04-22 1997-10-23 Merck Patent Gmbh Polyol-Zusammensetzung
DE19617487A1 (de) † 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
GB9716432D0 (en) * 1997-08-05 1997-10-08 Cerestar Holding Bv Tableting of erythritol
DE19819012A1 (de) * 1998-04-29 1999-11-25 Dynamit Nobel Ag Feuersichere, nicht explosionsfähige, Nitroglycerin und wasserfreie Lactose enthaltende Feststoffmischungen
US6296868B1 (en) * 1998-11-19 2001-10-02 Advanced Technology Pharmaceuticals Corporation Chewable tablets containing mannitol and aspartame
FR2787110B1 (fr) † 1998-12-11 2001-02-16 Roquette Freres Sorbitol pulverulent et son procede de preparation
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
CA2342121C (fr) * 2000-03-29 2010-05-25 Roquette Freres Mannitol pulverulent et son procede de preparation
FR2807034B1 (fr) * 2000-03-29 2002-06-14 Roquette Freres Mannitol pulverulent et son procede de fabrication
PT1343518E (pt) 2000-11-07 2009-08-03 Novartis Vaccines & Diagnostic Composições de interferão estabilizadas
WO2002069933A1 (fr) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Comprimés à délitement rapide dans la bouche
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
AU2003234555A1 (en) 2002-05-14 2003-12-02 Fmc Corporation Microcrystalline cewllulose compositions
ES2199061B1 (es) * 2002-06-10 2005-02-16 Laboratorios Vita, S.A. Comprimidos bucodispersables y procedimiento para su obtencion.
RU2209086C1 (ru) * 2002-08-09 2003-07-27 Нестерук Владимир Викторович Способ получения диуретического средства
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7282217B1 (en) * 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US20090317470A1 (en) * 2005-09-19 2009-12-24 Rupal Patel Oramucosal Pharmaceutical Dosage Form
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
JP2009520704A (ja) * 2005-12-21 2009-05-28 エーディーディー アドバンスト ドラッグ デリバリー テクノロジーズ リミテッド 水溶性担体を持つコアを含むペレット
DE602007011792D1 (de) * 2006-10-27 2011-02-17 Fmc Corp Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen
GB2450498A (en) 2007-06-26 2008-12-31 Schlumberger Holdings Battery powered rotary steerable drilling system
CA2734847C (en) 2008-08-18 2016-08-30 Mitsubishi Shoji Foodtech Co., Ltd. Novel excipient for mannitol tableting
WO2010077878A1 (en) * 2008-12-15 2010-07-08 Fleming And Company, Pharmaceuticals Rapidly dissolving vitamin formulation and methods of using the same
FR2949296B1 (fr) 2009-09-01 2011-11-18 Roquette Freres Procede de remplacement total ou partiel du talc dans les chewing-gums
FR2949462B1 (fr) * 2009-09-01 2011-12-16 Roquette Freres Poudre de cristaux de mannitol define, son procede de fabrication
JP2013539772A (ja) 2010-10-12 2013-10-28 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 非澱粉を基にしたソフトチュアブル
WO2013052118A1 (en) 2011-10-05 2013-04-11 Fmc Corporation Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
BR112014007366B1 (pt) 2011-10-05 2020-09-15 Dupont Nutrition Usa, Inc Processo para fabricar uma composição estabilizadora compreendendo extrusão em duas etapas, composição estabilizadora de celulose microcristalina e produto alimentício comestível e suspensão industrial compreendendo a mesma
WO2013085810A2 (en) 2011-12-09 2013-06-13 Fmc Corporation Co-attrited stabilizer composition
SMT202200255T1 (it) 2012-09-28 2022-07-21 Takeda Pharmaceuticals Co Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea
BE1021954B1 (nl) 2014-06-05 2016-01-28 Syral Belgium Nv Samenstelling van sorbitol met lage friabiliteit
TWI744224B (zh) * 2015-02-26 2021-11-01 日商武田藥品工業股份有限公司 固形製劑
FR3038836B1 (fr) * 2015-07-17 2017-07-14 Roquette Freres Granules de mannitol pour compression directe
SI3518932T1 (sl) 2016-09-30 2025-03-31 Takeda Pharmaceutical Company Limited Zdravljenje raka prostate
BR112022023937A2 (pt) 2020-05-29 2022-12-27 Myovant Sciences Gmbh Formas de dosagem oral sólidas de combinação de antagonistas do hormônio liberador de gonadotropina
MX2023011331A (es) * 2021-03-26 2023-10-03 Impact Therapeutics Shanghai Inc Capsula oral de inhibidor de parp y metodo de preparacion de la misma.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) * 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
US3341415A (en) * 1964-02-12 1967-09-12 Warner Lambert Pharmaceutical Pharmaceutical tablet excipients of solid particles of a binary solid solution of mannitol with a sugar
JPS5536646A (en) * 1978-09-06 1980-03-14 Arai Pump Mfg Co Ltd Double mechanical seal
US4293570A (en) * 1979-04-02 1981-10-06 Chimicasa Gmbh Process for the preparation of sweetener containing product
FR2571046B1 (fr) * 1984-10-03 1987-10-16 Roquette Freres Procede de preparation de mannitol granulaire directement compressible
FR2571045B1 (fr) * 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
JPS6185331A (ja) * 1984-10-04 1986-04-30 Fuji Kagaku Kogyo Kk 直打用賦形薬の製造法
JPS6185330A (ja) * 1984-10-04 1986-04-30 Fuji Kagaku Kogyo Kk 直打用賦形薬の製造法
DE69013689T2 (de) * 1990-11-29 1995-03-02 Wei Ming Pharmaceutical Mfg Co Hilfsträger für direkte Verpressung.
JPH06185330A (ja) * 1992-12-16 1994-07-05 Nissan Motor Co Ltd エンジンのオイルポンプ支持構造

Also Published As

Publication number Publication date
AU675732B2 (en) 1997-02-13
FR2710637A1 (fr) 1995-04-07
JP3492428B2 (ja) 2004-02-03
NO943586D0 (no) 1994-09-27
HU217453B (hu) 2000-01-28
ES2109635T3 (es) 1998-01-16
FI944464A0 (fi) 1994-09-27
CN1107516A (zh) 1995-08-30
AU7423994A (en) 1995-04-13
DE69407123T2 (de) 1998-04-23
NO302356B1 (no) 1998-02-23
CA2133012A1 (en) 1995-03-29
DE69407123D1 (de) 1998-01-15
US5573777A (en) 1996-11-12
EP0645096B1 (de) 1997-12-03
DK0645096T3 (da) 1998-05-04
JPH07184590A (ja) 1995-07-25
FI112356B (fi) 2003-11-28
CA2133012C (en) 2006-01-31
EP0645096A1 (de) 1995-03-29
KR950008457A (ko) 1995-04-17
GR3025720T3 (en) 1998-03-31
FR2710637B1 (fr) 1995-12-08
NO943586L (no) 1995-03-29
HUT70804A (en) 1995-11-28
KR100353433B1 (ko) 2002-12-11
HU9402773D0 (en) 1994-12-28
CN1046622C (zh) 1999-11-24
FI944464L (fi) 1995-03-29

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