ATE161174T1 - Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung - Google Patents
Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendungInfo
- Publication number
- ATE161174T1 ATE161174T1 AT94911799T AT94911799T ATE161174T1 AT E161174 T1 ATE161174 T1 AT E161174T1 AT 94911799 T AT94911799 T AT 94911799T AT 94911799 T AT94911799 T AT 94911799T AT E161174 T1 ATE161174 T1 AT E161174T1
- Authority
- AT
- Austria
- Prior art keywords
- solid preparation
- production
- release solid
- high release
- active agent
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE9300407A BE1006990A5 (nl) | 1993-04-22 | 1993-04-22 | Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE161174T1 true ATE161174T1 (de) | 1998-01-15 |
Family
ID=3886999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94911799T ATE161174T1 (de) | 1993-04-22 | 1994-04-21 | Feste zubereitung mit hoher freisetzung, ihre herstellung und verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6368634B1 (de) |
| EP (1) | EP0695172B1 (de) |
| JP (1) | JP2960169B2 (de) |
| AT (1) | ATE161174T1 (de) |
| AU (1) | AU6421594A (de) |
| BE (1) | BE1006990A5 (de) |
| CA (1) | CA2161016A1 (de) |
| DE (1) | DE69407404T2 (de) |
| DK (1) | DK0695172T3 (de) |
| ES (1) | ES2113095T3 (de) |
| GR (1) | GR3026338T3 (de) |
| WO (1) | WO1994023700A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| DE4318577A1 (de) * | 1993-06-04 | 1994-12-08 | Merck Patent Gmbh | Schmiermittelfreie, arzneimittelhaltige Tabletten |
| US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| CA2159419C (en) * | 1994-10-17 | 2006-07-04 | Pieter De Haan | Solid pharmaceutical composition comprising an excipient capable of binding water |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| NZ270439A (en) * | 1995-02-02 | 1996-04-26 | Bernard Charles Sherman | Solid slow release pharmaceutical composition: carrier is polyethylene glycol and hydrophilic gel-forming polymer |
| TWI225402B (en) * | 1996-03-13 | 2004-12-21 | Biochemie Gmbh | Auxiliary-free agglomerates |
| MX9801835A (es) | 1996-07-08 | 1998-08-30 | Mendell Co Inc Edward | Matriz de liberacion sostenida para medicamentos insolubles de dosis altas. |
| WO1999017743A1 (en) * | 1997-10-07 | 1999-04-15 | Fuisz Technologies Ltd. | Dosage forms having improved release properties |
| US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| FR2775597B1 (fr) * | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
| CA2348452A1 (en) * | 1998-10-27 | 2000-05-04 | Biovail Technologies Ltd. | Microparticles containing peg and/or peg glyceryl esters |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| WO2001078725A2 (en) * | 2000-04-13 | 2001-10-25 | Synthon B.V. | Modified release formulations containing a hypnotic agent |
| SE0200154D0 (sv) * | 2002-01-21 | 2002-01-21 | Galenica Ab | New process |
| WO2003072085A1 (fr) * | 2002-02-27 | 2003-09-04 | Shionogi & Co., Ltd. | Preparations solides contenant un medicament a peine soluble dans l'eau d'une meilleure absorbabilite |
| GB0205253D0 (en) * | 2002-03-06 | 2002-04-17 | Univ Gent | Immediate release pharmaceutical granule compositions and a continuous process for making them |
| US20060003002A1 (en) * | 2003-11-03 | 2006-01-05 | Lipocine, Inc. | Pharmaceutical compositions with synchronized solubilizer release |
| US20070190141A1 (en) * | 2006-02-16 | 2007-08-16 | Aaron Dely | Extended release opiate composition |
| GB0612695D0 (en) * | 2006-06-27 | 2006-08-09 | Univ Gent | Process for preparing a solid dosage form |
| EP2051696A2 (de) * | 2006-08-18 | 2009-04-29 | Morton Grove Pharmaceuticals, Inc. | Stabile flüssige levetiracetam-zusammensetzungen und verfahren |
| CA2718416C (en) * | 2008-03-13 | 2018-01-02 | Mallinckrodt Inc. | Multi-function, foot-activated controller for imaging system |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| WO2016033549A2 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
| WO2020018974A1 (en) | 2018-07-20 | 2020-01-23 | Lipocine Inc. | Liver disease |
| EP3991750A4 (de) | 2019-06-26 | 2022-08-03 | Ricoh Company, Ltd. | Pharmazeutische zusammensetzung |
| US20220023216A1 (en) | 2019-06-26 | 2022-01-27 | Ricoh Company, Ltd. | Instantly soluble particle and method for producing the same |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3146167A (en) * | 1961-10-05 | 1964-08-25 | Smith Kline French Lab | Method of preparing sustained release pellets and products thereof |
| GB1148802A (en) * | 1965-06-18 | 1969-04-16 | Eastman Kodak Co | Microcrystalline cellulose granules containing useful oils |
| CH523017A (de) * | 1969-11-21 | 1972-05-31 | Agripat Sa | Schädlingsbekämpfungsmittel |
| US3655864A (en) * | 1970-09-21 | 1972-04-11 | Smith Kline French Lab | Glyceryl tristerate and higher fatty acid mixture for improving digestive absorption |
| GB1367608A (en) * | 1973-03-09 | 1974-09-18 | Biolog Concepts Inc | Oral pharmaceutical dosage form |
| USRE33963E (en) * | 1981-10-29 | 1992-06-16 | Bayer Aktiengesellschaft | Solid rapidly released medicament preparations containing dihydropyridines, and processes for their preparation |
| FR2581541B1 (fr) * | 1985-05-09 | 1988-05-20 | Rhone Poulenc Sante | Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation |
| LU86099A1 (fr) * | 1985-09-30 | 1987-04-02 | Pharlyse | Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant |
| SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
| DD249186A1 (de) * | 1986-05-26 | 1987-09-02 | Univ Halle Wittenberg | Herstellungsverfahren einer neuen glibenclamid-arzneiform mit hoher bioverfuegbarkeit |
| EP0272336B1 (de) * | 1986-12-18 | 1991-10-23 | Kurt H. Prof. Dr. Bauer | Gegenüber Lichteinfluss stabilisiertes Nifedipin-Konzentrat und Verfahren zu seiner Herstellung |
| AR240018A1 (es) * | 1987-10-07 | 1990-01-31 | Merrell Pharma Inc | Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol. |
| HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
| EP0418596A3 (en) | 1989-09-21 | 1991-10-23 | American Cyanamid Company | Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form |
| US5169645A (en) * | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
| SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
| US5288505A (en) * | 1991-06-26 | 1994-02-22 | Galephar P.R., Inc., Ltd. | Extended release form of diltiazem |
| JPH0597672A (ja) * | 1991-10-08 | 1993-04-20 | Terumo Corp | アミド誘導体含有固形製剤およびその製造方法 |
-
1993
- 1993-04-22 BE BE9300407A patent/BE1006990A5/nl not_active IP Right Cessation
-
1994
- 1994-04-21 EP EP94911799A patent/EP0695172B1/de not_active Expired - Lifetime
- 1994-04-21 WO PCT/BE1994/000029 patent/WO1994023700A1/en not_active Ceased
- 1994-04-21 ES ES94911799T patent/ES2113095T3/es not_active Expired - Lifetime
- 1994-04-21 AT AT94911799T patent/ATE161174T1/de not_active IP Right Cessation
- 1994-04-21 DE DE69407404T patent/DE69407404T2/de not_active Expired - Fee Related
- 1994-04-21 AU AU64215/94A patent/AU6421594A/en not_active Abandoned
- 1994-04-21 JP JP6522562A patent/JP2960169B2/ja not_active Expired - Fee Related
- 1994-04-21 DK DK94911799T patent/DK0695172T3/da active
- 1994-04-21 CA CA002161016A patent/CA2161016A1/en not_active Abandoned
- 1994-04-21 US US08/537,793 patent/US6368634B1/en not_active Expired - Fee Related
-
1998
- 1998-03-12 GR GR980400506T patent/GR3026338T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2960169B2 (ja) | 1999-10-06 |
| ES2113095T3 (es) | 1998-04-16 |
| GR3026338T3 (en) | 1998-06-30 |
| EP0695172A1 (de) | 1996-02-07 |
| US6368634B1 (en) | 2002-04-09 |
| EP0695172B1 (de) | 1997-12-17 |
| WO1994023700A1 (en) | 1994-10-27 |
| DE69407404T2 (de) | 1998-07-02 |
| AU6421594A (en) | 1994-11-08 |
| BE1006990A5 (nl) | 1995-02-07 |
| JPH09500093A (ja) | 1997-01-07 |
| DK0695172T3 (da) | 1998-08-24 |
| DE69407404D1 (de) | 1998-01-29 |
| CA2161016A1 (en) | 1994-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |