ATE161824T1 - Anticonvulsives aminosäurederivat - Google Patents

Anticonvulsives aminosäurederivat

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Publication number
ATE161824T1
ATE161824T1 AT92913324T AT92913324T ATE161824T1 AT E161824 T1 ATE161824 T1 AT E161824T1 AT 92913324 T AT92913324 T AT 92913324T AT 92913324 T AT92913324 T AT 92913324T AT E161824 T1 ATE161824 T1 AT E161824T1
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Austria
Prior art keywords
anticonvulsive
amino acid
acid derivative
compounds
cns
Prior art date
Application number
AT92913324T
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English (en)
Inventor
Harold L Kohn
Darrell Watson
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Res Corp Technologies Inc
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Publication of ATE161824T1 publication Critical patent/ATE161824T1/de

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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AT92913324T 1991-06-04 1992-06-04 Anticonvulsives aminosäurederivat ATE161824T1 (de)

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US07/710,610 US5378729A (en) 1985-02-15 1991-06-04 Amino acid derivative anticonvulsant

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JP2002241355A (ja) 2002-08-28
EP0592490A1 (de) 1994-04-20
AU2162192A (en) 1993-01-08
JPH06510985A (ja) 1994-12-08
DE69223965T2 (de) 1998-04-30
EP0592490B1 (de) 1998-01-07
JP3330374B2 (ja) 2002-09-30
CA2110693A1 (en) 1992-12-10
CA2110693C (en) 2003-05-20
DE69223965D1 (de) 1998-02-12
AU657985B2 (en) 1995-03-30
WO1992021648A1 (en) 1992-12-10
EP0592490A4 (en) 1994-08-17
US5378729A (en) 1995-01-03

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