ATE162632T1 - Messung von blutplättchenaktivitäten - Google Patents

Messung von blutplättchenaktivitäten

Info

Publication number
ATE162632T1
ATE162632T1 AT93912364T AT93912364T ATE162632T1 AT E162632 T1 ATE162632 T1 AT E162632T1 AT 93912364 T AT93912364 T AT 93912364T AT 93912364 T AT93912364 T AT 93912364T AT E162632 T1 ATE162632 T1 AT E162632T1
Authority
AT
Austria
Prior art keywords
platelets
methods
measurement
blood
procoagulant
Prior art date
Application number
AT93912364T
Other languages
English (en)
Inventor
Hendrik C Hemker
Robert J Wagenvoord
Original Assignee
Dade Produktions Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Produktions Ag filed Critical Dade Produktions Ag
Application granted granted Critical
Publication of ATE162632T1 publication Critical patent/ATE162632T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93912364T 1992-06-03 1993-06-03 Messung von blutplättchenaktivitäten ATE162632T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/892,865 US5266462A (en) 1992-06-03 1992-06-03 Measurement of platelet activities

Publications (1)

Publication Number Publication Date
ATE162632T1 true ATE162632T1 (de) 1998-02-15

Family

ID=25400634

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93912364T ATE162632T1 (de) 1992-06-03 1993-06-03 Messung von blutplättchenaktivitäten

Country Status (9)

Country Link
US (1) US5266462A (de)
EP (1) EP0605674B1 (de)
JP (1) JP3143694B2 (de)
AT (1) ATE162632T1 (de)
AU (1) AU658073B2 (de)
CA (1) CA2114719C (de)
DE (1) DE69316572T2 (de)
ES (1) ES2114053T3 (de)
WO (1) WO1993024840A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9306053D0 (en) * 1993-03-24 1993-05-12 Nycomed Pharma As Method and assay
ES2139957T3 (es) 1994-07-23 2000-02-16 Roche Diagnostics Gmbh Metodo para la determinacion del estado pretrombotico.
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
WO1997041432A1 (en) * 1996-04-30 1997-11-06 Medtronic, Inc. Method for determining platelet inhibitor response
US6221672B1 (en) 1996-04-30 2001-04-24 Medtronic, Inc. Method for determining platelet inhibitor response
US5951951A (en) 1997-04-30 1999-09-14 Medtronic, Inc. Platelet function evaluation technique for citrated whole blood
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
AU8388098A (en) * 1997-07-11 1999-02-08 Mount Sinai School Of Medicine Of The City University Of New York, The Assays for diagnosis of thrombophilic disease
US20040219681A1 (en) * 1997-09-18 2004-11-04 Ridgway Helen Jane Two-tube method and system for platelet function analysis using platelet count
US20040219682A1 (en) * 1997-09-18 2004-11-04 Ridgway Helen Jane Single-tube method and system for platelet function analysis
US6410337B1 (en) * 1997-09-18 2002-06-25 Helena Laboratories Corporation Method of platlet function analysis using platelet count
AU2900599A (en) * 1998-03-10 1999-09-27 Baxter International Inc. Thrombin preparation and products and fibrin sealant methods employing same
WO2001044493A2 (en) * 1999-12-15 2001-06-21 Pentapharm Ag Hematological assay and reagent
JP2005538383A (ja) * 2002-09-10 2005-12-15 プラコア・インコーポレーテッド 血小板機能を監視する方法および装置
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7790362B2 (en) 2003-07-08 2010-09-07 Accumetrics, Inc. Controlled platelet activation to monitor therapy of ADP antagonists
US7422905B2 (en) 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7439069B2 (en) 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7399637B2 (en) 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
CA2566411A1 (en) * 2004-05-11 2005-11-24 Heptest Laboratories, Inc. Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities
WO2005116623A2 (en) * 2004-05-17 2005-12-08 Medtronic, Inc. Point of care heparin determination system
EP1875232A2 (de) * 2005-04-25 2008-01-09 PlaCor, Inc. Verfahren und vorrichtungen zur überwachung der blutplättchenfunktion
US20100099130A1 (en) * 2006-10-25 2010-04-22 Placor Inc. Methods and devices for monitoring platelet function

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900679A (en) * 1983-01-26 1990-02-13 University Of Medicine And Dentistry Of New Jersey Method for determining the existence and/or the monitoring of a pathological condition in a mammal and a test kit therefor
US4728660A (en) * 1984-06-11 1988-03-01 University Of Miami Method of treating diseases arising from platelet hyperactivation
ES8702431A1 (es) * 1984-09-21 1986-12-16 Boehringer Ingelheim Int Procedimiento para preparar una proteina inhibidora de la coagulacion de la sangre
US5066788A (en) * 1984-09-21 1991-11-19 Boehringer Ingelheim International Gmbh Blood coagulation inhibiting proteins, processes for preparing them and their uses
US4871677A (en) * 1985-02-25 1989-10-03 Hemotec, Inc. Method of collecting and analyzing a sample of blood when monitoring heparin therapy
US5017556A (en) * 1986-11-04 1991-05-21 Genentech, Inc. Treatment of bleeding disorders using lipid-free tissue factor protein
US4880788A (en) * 1987-10-30 1989-11-14 Baylor College Of Medicine Method for preventing and treating thrombosis
US5120537A (en) * 1989-06-14 1992-06-09 Oklahoma Medical Research Foundation Factor xa based anticoagulant compositions

Also Published As

Publication number Publication date
DE69316572T2 (de) 1998-09-10
AU658073B2 (en) 1995-03-30
JP3143694B2 (ja) 2001-03-07
ES2114053T3 (es) 1998-05-16
DE69316572D1 (de) 1998-02-26
JPH06509479A (ja) 1994-10-27
AU4409093A (en) 1993-12-30
CA2114719C (en) 1997-08-26
EP0605674A1 (de) 1994-07-13
CA2114719A1 (en) 1993-12-09
US5266462A (en) 1993-11-30
WO1993024840A1 (en) 1993-12-09
EP0605674B1 (de) 1998-01-21

Similar Documents

Publication Publication Date Title
ATE162632T1 (de) Messung von blutplättchenaktivitäten
DE3771185D1 (de) Optischer detektor zur gleichzeitigen erfassung von herzschlag und toraxbewegung.
ATE100209T1 (de) Antikoerper verwendende diagnostische methoden.
DE3856076D1 (de) Nachweis von flüssigkeitsströmungen
FI903574A0 (fi) Laite verinäytteen hyytymisajan määrittämiseksi
FI875609A7 (fi) Testikantaja kehon nesteiden ainesosasten analyyttistä määritystä varten.
DK531887A (da) Mutagenese- og screeningsfremgangsmaade samt produkt
ATE76508T1 (de) Vorrichtung zur feststellung von okkultem blut.
NO164202C (no) Vaeskeloesning for paavisning av peroksidaselignende aktivitet, samt fremgangsmaate og diagnosesett for paavisning av slik aktivitet.
NL193719B (nl) Inrichting voor het bepalen van stenosis van bloedvaten.
DE3765138D1 (de) Mehrschichtiges element zur quantitativen analyse von immunoreagenzien.
DE3884456D1 (de) Vorrichtung zur detektion und richtungsbestimmung von licht.
DE68920769D1 (de) Gerät zur Messung der Geschwindigkeit von Organen und der Blutströmung durch Korrelationsverfahren.
DE69013294D1 (de) Doppler-Radar zur Entdeckung und Ortung von Hubschraubern.
DE58903503D1 (de) System zur erfassung der position von beweglichen maschinenteilen.
IT8183349A0 (it) Dei fenomeni di emocoagulazione, dispositivo di rivelazione ottica concentrazione, ed aggregazione delle piastrine o simili.
DK226889A (da) Alkoholpeptidderivat samt anvendelse deraf til mindskning af blodkoagulation
DE3481556D1 (de) System zur unterscheidung und zur lagebestimmung von objekten.
DE3852625D1 (de) Vektoren und Verbindungen zur Expression von Zymogen-Formen von menschlichem Protein C.
IT1203671B (it) Reagente per la determinazione del la funzione di coagulazione del sangue e procedimento per la sua preparazione
IT8921788A0 (it) Reattivo utile per la rilevazione e la determinazione quantitativa dei leucociti in fluidi biologici.
FI895215A7 (fi) Menetelmä antitrombiini III:n biologisen aktiivisuuden määrittämiseksi ja reagenssi sitä varten
DE69026039D1 (de) System zum Festlegen der Betriebsbedingungen von Zentrifugenrotoren
DE3671521D1 (de) Vorrichtung zur probenentnahme von blut und zur messung der geschwindigkeit der sedimentationsrate der erythrocyten.
DE68910100D1 (de) Mittel zur Bluttrennung.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties