ATE163264T1 - Verwendung von n,n'-bis 3-(ethylamino)propyl-1,7- heptandiamin und einem zytotoxischen mittel - Google Patents

Verwendung von n,n'-bis 3-(ethylamino)propyl-1,7- heptandiamin und einem zytotoxischen mittel

Info

Publication number
ATE163264T1
ATE163264T1 AT91121354T AT91121354T ATE163264T1 AT E163264 T1 ATE163264 T1 AT E163264T1 AT 91121354 T AT91121354 T AT 91121354T AT 91121354 T AT91121354 T AT 91121354T AT E163264 T1 ATE163264 T1 AT E163264T1
Authority
AT
Austria
Prior art keywords
antineoplastic
heptanediamine
ethylamino
propyl
bis
Prior art date
Application number
AT91121354T
Other languages
English (en)
Inventor
Nellikunja J Prakash
Terry L Bowlin
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE163264T1 publication Critical patent/ATE163264T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91121354T 1990-12-13 1991-12-12 Verwendung von n,n'-bis 3-(ethylamino)propyl-1,7- heptandiamin und einem zytotoxischen mittel ATE163264T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62681490A 1990-12-13 1990-12-13

Publications (1)

Publication Number Publication Date
ATE163264T1 true ATE163264T1 (de) 1998-03-15

Family

ID=24511975

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91121354T ATE163264T1 (de) 1990-12-13 1991-12-12 Verwendung von n,n'-bis 3-(ethylamino)propyl-1,7- heptandiamin und einem zytotoxischen mittel

Country Status (11)

Country Link
EP (1) EP0490380B1 (de)
JP (1) JPH04275233A (de)
KR (1) KR100195423B1 (de)
AT (1) ATE163264T1 (de)
AU (1) AU648846B2 (de)
DE (1) DE69128926T2 (de)
DK (1) DK0490380T3 (de)
ES (1) ES2113870T3 (de)
GR (1) GR3026432T3 (de)
IE (1) IE914331A1 (de)
ZA (1) ZA919695B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69728220T2 (de) * 1996-01-31 2005-01-27 Japan Science And Technology Corp., Kawaguchi Antitumormittel mit silizium und stickstoff enthaltenden verbindungen als hauptbestandteil
US6274561B1 (en) 1997-01-29 2001-08-14 Japan Science & Technology Corp. Antitumor agents comprising as the principal compounds containing silicon and nitrogen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA88600B (en) * 1987-02-03 1988-07-28 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
ATE120447T1 (de) * 1989-01-10 1995-04-15 Merrell Dow Pharma Polyamin-derivate als antineoplastische mittel.
AU628174B2 (en) * 1989-05-23 1992-09-10 Merrell Dow Pharmaceuticals Inc. A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Also Published As

Publication number Publication date
KR920011481A (ko) 1992-07-24
DK0490380T3 (da) 1998-09-23
ES2113870T3 (es) 1998-05-16
IE914331A1 (en) 1992-06-17
KR100195423B1 (ko) 1999-06-15
DE69128926T2 (de) 1998-06-04
JPH04275233A (ja) 1992-09-30
DE69128926D1 (de) 1998-03-26
EP0490380A2 (de) 1992-06-17
AU648846B2 (en) 1994-05-05
AU8890791A (en) 1992-06-18
GR3026432T3 (en) 1998-06-30
EP0490380B1 (de) 1998-02-18
EP0490380A3 (en) 1993-03-10
ZA919695B (en) 1992-09-30

Similar Documents

Publication Publication Date Title
HU0301601D0 (en) Bis(n-substituted)-staurosporine derivatives, their use and pharmaceutical composition containing thereof
ZA93234B (en) Flavour-masked pharmaceutical compositions
ZA90963B (en) Diphenylheteroalkyl derivatives,the preparation thereof and drugs and cosmetics prepared therefrom
DE69528710D1 (de) 2-substituierte 1,2,5-thiadiazolidin-3-on-1,1-dioxiden, zusammensetzung und deren verwendung
ATE85757T1 (de) Piroxicam in waessrigen loesungen enthaltende arzneizubereitungen und verfahren zu deren herstellung.
PT88275A (pt) Processo para a preparacao de composicoes farmaceuticas contendo 5-amino ou amino substituido-1,2,3-triazois uteis como agentes antiproliferativos
DK0501705T3 (da) Anvendelse af tomoxetin til behandling af sygdomme i de nedre urinveje
ATE161531T1 (de) Acridine-1,8-dionderivate als therapeutisches mittel
ATE99945T1 (de) Verwendung von 5'-deoxy-5'-methylthioadenosin s- adenosylmethionin und dessen salzen zur herstellung von seborrhea vermindernden arzneimitteln.
DK393188A (da) Farmaceutisk praeparat til intranasal administrering
ATE114974T1 (de) Abgabe von cytotoxischen mitteln.
DE3887068D1 (de) 2,2-Dimethylchromenderivate, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
ATE163264T1 (de) Verwendung von n,n'-bis 3-(ethylamino)propyl-1,7- heptandiamin und einem zytotoxischen mittel
ES2044100T4 (es) Ciertas combinaciones de antagonistas del "paf" y antihistaminicos y metodos.
DE69003466D1 (de) Substituierte Thienopyrimidin-Derivate, deren Herstellung, pharmazeutische Zusammensetzungen und medizinische Verwendung.
GR3022706T3 (en) Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases
ATE65408T1 (de) Arzneimittel enthaltend in kombination interferon und 1-desoxy-piperidinosen, verfahren zu deren herstellung und deren verwendung.
SE8802323D0 (sv) 8alfa-acylaminoergoline, its preparation and pharmaceutical compositions containing it
ITMI911845A1 (it) Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico.
ATA234589A (de) Neue 2-methoxycarbonyl substituierte n,n'-di(trimethoxybenzoyl)piperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
FR2710062B1 (fr) Dérivés d'acide 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur préparation et les médicaments les contenant.
DE69409633D1 (de) Transdermal behandlung von krebs mit wasserunlöslichem s-camtothecin mit geschlossenem lactoring
ATE10095T1 (de) 10-substituierte 5-cyanmethylen-10,11-dihydrodibenzo-(a,d)-cycloheptene, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel.
IE900936L (en) Improvements in chemical compounds
FR2715658B1 (fr) Dérivés de N-(3-aminopropyl)-N-phényl-5,6,7,8-tétrahydronaphtalène-2-carboxamide, leur préparation et leur application en thérapeutique.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee