ATE164881T1 - Mikroorganismen und verfahren zur herstellung von 3-alpha, 7-alpha-dihydroxy-12-keto-cholansäure - Google Patents

Mikroorganismen und verfahren zur herstellung von 3-alpha, 7-alpha-dihydroxy-12-keto-cholansäure

Info

Publication number
ATE164881T1
ATE164881T1 AT92309730T AT92309730T ATE164881T1 AT E164881 T1 ATE164881 T1 AT E164881T1 AT 92309730 T AT92309730 T AT 92309730T AT 92309730 T AT92309730 T AT 92309730T AT E164881 T1 ATE164881 T1 AT E164881T1
Authority
AT
Austria
Prior art keywords
alpha
keto
dihydroxy
microorganisms
cholanic acid
Prior art date
Application number
AT92309730T
Other languages
English (en)
Inventor
Hiromi Kimura
Akio Okamura
Hiroshi Kawaide
Original Assignee
Tokyo Tanabe Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Tanabe Co filed Critical Tokyo Tanabe Co
Application granted granted Critical
Publication of ATE164881T1 publication Critical patent/ATE164881T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92309730T 1991-10-24 1992-10-23 Mikroorganismen und verfahren zur herstellung von 3-alpha, 7-alpha-dihydroxy-12-keto-cholansäure ATE164881T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03277799A JP3082973B2 (ja) 1991-10-24 1991-10-24 ３α，７α−ジヒドロキシ−１２−ケト−５β−コラン酸の製造方法

Publications (1)

Publication Number Publication Date
ATE164881T1 true ATE164881T1 (de) 1998-04-15

Family

ID=17588444

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92309730T ATE164881T1 (de) 1991-10-24 1992-10-23 Mikroorganismen und verfahren zur herstellung von 3-alpha, 7-alpha-dihydroxy-12-keto-cholansäure

Country Status (9)

Country Link
US (1) US5451510A (de)
EP (1) EP0539216B1 (de)
JP (1) JP3082973B2 (de)
KR (1) KR0169498B1 (de)
AT (1) ATE164881T1 (de)
AU (1) AU662359B2 (de)
CA (1) CA2081057A1 (de)
DE (1) DE69225039T2 (de)
ES (1) ES2113928T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2070720A1 (en) * 1991-06-12 1992-12-13 Hiromi Kimura Microorganisms having a conversion ability to bile acids and method for preparing bile acids

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2236574A (en) * 1937-06-03 1941-04-01 Schering Corp Biochemical manufacture of ketosteroids
US2341110A (en) * 1939-05-12 1944-02-08 Schering Corp Process for the manufacture of ketosteroids
US2905592A (en) * 1955-07-27 1959-09-22 Pfizer & Co C Oxidation of steroids by mycobacteria
US2992973A (en) * 1958-08-12 1961-07-18 Takeda Pharmaceutical Dehydrogenation of steroids by azotobacter microorganisms
US3037913A (en) * 1960-05-06 1962-06-05 American Cyanamid Co Microbiological dehydrogenation of delta steroids of the pregnene series using bacterium mycoides
US3037914A (en) * 1960-05-06 1962-06-05 American Cyanamid Co Bacterial production of triamcinolone by bacterial formulations
DE1904544C3 (de) * 1969-01-27 1978-05-18 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur mikrobiologischen Umwandlung von 3 ß-Hydroxy-5,6- epoxysteroiden in 6-Hydroxy-3-KetoA<·4 -Steroide
US3801460A (en) * 1970-12-18 1974-04-02 Merck & Co Inc Simultaneous steroid oxygenation and 1-dehydrogenation with bacillus cereus
JPS578796A (en) * 1980-06-17 1982-01-18 Kuraray Co Ltd Preparation of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanic acid and/or its salt
JPS578781A (en) * 1980-12-29 1982-01-18 Kuraray Co Ltd Microorganism producing 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanic acid
DE3241829A1 (de) * 1982-11-09 1984-05-10 Schering AG, 1000 Berlin und 4709 Bergkamen Biokatalysator
JPS61282099A (ja) * 1985-06-07 1986-12-12 Showa Denko Kk １２−ケト−３α，７α−ジヒドロキシコラン酸の製造方法
CA2070720A1 (en) * 1991-06-12 1992-12-13 Hiromi Kimura Microorganisms having a conversion ability to bile acids and method for preparing bile acids

Also Published As

Publication number Publication date
CA2081057A1 (en) 1993-04-25
AU2714492A (en) 1993-04-29
EP0539216A3 (en) 1994-08-17
JPH05111391A (ja) 1993-05-07
EP0539216A2 (de) 1993-04-28
DE69225039D1 (de) 1998-05-14
DE69225039T2 (de) 1998-07-30
EP0539216B1 (de) 1998-04-08
US5451510A (en) 1995-09-19
KR0169498B1 (ko) 1999-01-15
ES2113928T3 (es) 1998-05-16
JP3082973B2 (ja) 2000-09-04
AU662359B2 (en) 1995-08-31
KR930008137A (ko) 1993-05-21

Similar Documents

Publication Publication Date Title
AU7508794A (en) Novel lipase, microorganism producing the lipase, process for producing the lipase, and use of the lipase
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
EP0386757A3 (en) Biodegradable poly (phosphate esters)
IL86895A (en) De-mannosyl teicoplanin derivativesuseful as antibioticsand animal growthsupplements, and theirpreparation
ATE108826T1 (de) Heparinase produzierender mikroorganismus des stammes bacillus, neue heparinase und verfahren zu ihrer herstellung.
ATE63338T1 (de) Verfahren zur herstellung von 6hydroxynikotins|ure.
GR3031149T3 (en) Process for the manufacture of (s)-3-amino-1-substituted-pyrrolidines.
ATE169060T1 (de) Lactobacillus sake ähnliche stämme herstellung und verwendung von deren exopolysacchariden
AU634003B2 (en) 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
ATE164881T1 (de) Mikroorganismen und verfahren zur herstellung von 3-alpha, 7-alpha-dihydroxy-12-keto-cholansäure
DE69333302D1 (de) Mikroorganismen, ihre herstellung und verwendung
AU4174496A (en) Silylation process
DE68913128D1 (de) Verfahren zur Herstellung von L-Alanin-Dehydrogenase und Mikroorganismusstamm des Genus Sporolactobacillus.
CA2084384A1 (en) Dna coding for uricase and process for producing uricase
NO903338D0 (no) Fremgangsmaate for mikrobiologisk fremstilling av l-carnitin.
DE69013425D1 (de) Pseudomonasmutant, yzh-Stamm und Verfahren zur Herstellung der 851yzh-Nährlösung mittels dieses Stammes.
HUT46361A (en) Process for producing a 42867 antibiotic and pharmaceutical compositions comprising it
DK53488A (da) Cytochrom-p-450-enzymer samt fremgangsmaade til fremstilling heraf
EP0647654A3 (de)
AU3215989A (en) Process for activating enzymes and promoting synthesis in organisms
GR3034688T3 (en) Use of 6,7-substituted-2-aminotetralines for preparing pharmaceutical compositions useful for the treatment of septic shock, and antipyretic and antiinflammatory pharmaceutical compositions
CA2014884A1 (en) 5,11-dihydro-6h-pyrido[2,3-b][1,4]benzodiazepin-6-ones and -thiones and their use in the prevention or treatment of aids
DE69802171D1 (de) Verfahren zur herstellung von 10,11-dihydro-5h-dibenzo(a,d)cyclohept-5-enen und ihren derivaten
AU3703795A (en) Chondrocyte cell-lines
FR2657882B1 (fr) Fragments d&#39;adn comprenant le gene de la 1-deshydrogenase, micro-organismes transformes par lesdits fragments et applications desdits fragments et micro-organismes.