ATE165980T1 - Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren - Google Patents

Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren

Info

Publication number
ATE165980T1
ATE165980T1 AT88908472T AT88908472T ATE165980T1 AT E165980 T1 ATE165980 T1 AT E165980T1 AT 88908472 T AT88908472 T AT 88908472T AT 88908472 T AT88908472 T AT 88908472T AT E165980 T1 ATE165980 T1 AT E165980T1
Authority
AT
Austria
Prior art keywords
mannose binding
fragments
binding protein
human
nuclic acid
Prior art date
Application number
AT88908472T
Other languages
English (en)
Inventor
Raymond Alan Brian Ezekowitz
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22206319&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE165980(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Application granted granted Critical
Publication of ATE165980T1 publication Critical patent/ATE165980T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT88908472T 1987-08-20 1988-08-05 Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren ATE165980T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8762887A 1987-08-20 1987-08-20

Publications (1)

Publication Number Publication Date
ATE165980T1 true ATE165980T1 (de) 1998-05-15

Family

ID=22206319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88908472T ATE165980T1 (de) 1987-08-20 1988-08-05 Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren

Country Status (7)

Country Link
EP (1) EP0375736B1 (de)
JP (1) JP2868777B2 (de)
AT (1) ATE165980T1 (de)
DE (1) DE3856180T2 (de)
DK (1) DK43890A (de)
FI (1) FI900808A7 (de)
WO (1) WO1989001519A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006010A1 (en) * 1989-10-11 1991-05-02 Institute Of Child Health Diagnostic procedure
GB9023907D0 (en) * 1990-11-02 1990-12-12 Mallucci Livio Cell growth inhibitors
AU9040591A (en) * 1990-11-06 1992-05-26 Children's Medical Center Corporation Soluble mannose receptor peptides
CA2056118A1 (en) * 1990-12-24 1992-06-25 Kendra B. Eager Monoclonal antibodies which bind mannose binding protein
JP3369555B2 (ja) * 1991-07-31 2003-01-20 アンテックス バイオロジックス インコーポレーテッド 薬剤および他の作用剤を標的へ向かわせるレセプター複合体
AU6623096A (en) 1995-07-27 1997-02-26 Imperial College Of Science, Technology And Medicine Methods of predicting the outcome of infection
JP3990736B2 (ja) 1997-08-21 2007-10-17 タカラバイオ株式会社 制がん剤
JPH11206378A (ja) 1998-01-23 1999-08-03 Fuso Pharmaceutical Industries Ltd 組換えヒトマンナン結合タンパク質およびその製造方法
US7049099B2 (en) 1998-01-23 2006-05-23 Fuso Pharmaceutical Industries, Ltd. Recombinant human mannan-binding proteins and producing method of the same
JP3878737B2 (ja) 1998-01-23 2007-02-07 扶桑薬品工業株式会社 新規コレクチン
JP4707231B2 (ja) * 1998-06-10 2011-06-22 スタテンズ セーラム インスティテュート マンナン結合レクチンを製造するための精製方法及びｍｂｌ医薬品
US7273925B1 (en) 1998-12-15 2007-09-25 Brigham And Women's Hospital, Inc. Methods and products for regulating lectin complement pathway associated complement activation
JP2002532079A (ja) * 1998-12-15 2002-10-02 ザ ブライハム アンド ウイミンズ ホスピタル， インコーポレイテッド 補体活性化に関連するレクチン補体経路を調節するための方法および産物
CN1899603B (zh) * 1999-05-14 2010-09-08 斯蒂芬·蒂尔 甘露聚糖-结合型凝集素(mbl)在免疫受损个体的治疗中的新意义
DE60030173T2 (de) 1999-05-14 2007-08-23 Steffen Thiel Neue Indikationen für Mannan-binding Lectin (MBL) zur Behandlung von immungeschwächten Patienten
WO2001059107A1 (en) 2000-02-14 2001-08-16 Fuso Pharmaceutical Industries, Ltd. Novel scavenger receptors
AU4884001A (en) 2000-04-21 2001-11-07 Fuso Pharmaceutical Ind Novel collectins
RU2003104524A (ru) * 2000-07-13 2005-01-20 Дженс Христиан ДЖЕНСЕНИУС (DK) Masp-2, комплемент-связывающий фермент и его применение
EP1186299A1 (de) * 2000-09-12 2002-03-13 Universitair Medisch Centrum Utrecht Diagnose, Verbeugung und/oder Behandlung von Atherosklerose, Infectionen und Störungen des Immunsystems
WO2007085057A1 (en) * 2006-01-25 2007-08-02 The Council Of The Queensland Institute Of Medical Research A medical protocol
WO2007095154A2 (en) 2006-02-10 2007-08-23 The Brigham And Women's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
SG10201503351RA (en) 2010-01-19 2015-06-29 Harvard College Engineered Opsonin for Pathogen Detection and Treatment
AU2012284097B2 (en) 2011-07-18 2017-08-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
WO2013130875A1 (en) 2012-02-29 2013-09-06 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
WO2014144325A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
EP3331549B1 (de) 2015-08-06 2020-12-23 President and Fellows of Harvard College Verbesserte mikrobenbindende moleküle und verwendungen davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573529B2 (en) * 1982-05-12 1988-06-16 President And Fellows Of Harvard College Hybrid proteins

Also Published As

Publication number Publication date
FI900808A0 (fi) 1990-02-19
JPH02504581A (ja) 1990-12-27
DK43890D0 (da) 1990-02-19
DE3856180D1 (de) 1998-06-18
EP0375736B1 (de) 1998-05-13
WO1989001519A1 (en) 1989-02-23
FI900808A7 (fi) 1990-02-19
DK43890A (da) 1990-02-19
EP0375736A1 (de) 1990-07-04
DE3856180T2 (de) 1998-09-03
JP2868777B2 (ja) 1999-03-10

Similar Documents

Publication Publication Date Title
ATE165980T1 (de) Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren
DE69634912D1 (de) Intrazellulare domäne des her-2/neu proteins, für die prevention oder behandlung von bösartigen tumoren
WO2003057158A3 (en) Method of treating apoptosis and compositions thereof
WO2004000997A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
DE68925226D1 (de) Monoklonale Antikörper
ATE354638T1 (de) Menschlicher gewebsinhibitor von metalloproteinase-4
WO2002050277A3 (en) Protein and nucleic acids encoding same
NL300830I1 (nl) Protein Q, een recombinant chimeer eiwit, bestaande uit vijf antigenefragmenten van vier verschillende Leishmania infantum (zymodeme Mon-1) eiwitten
ES2168361T3 (es) Secuencias de adn para metaloproteasas de la matriz, su preparacion y empleo.
WO2002057453A3 (en) Polypetides and nucleic acids encoding same
GEP20043386B (en) β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same
ATE166656T1 (de) Humanes galanin, cdna-klone die für humanes galanin kodieren und eine methode humanes galamin herzustellen
DK1261712T3 (da) Proteiner benævnt FXTRC og nucleinsyrer kodende for samme
SE9002212D0 (sv) Igg binding protein
WO2003022998A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
NO980122D0 (no) Emaljematriksrelatert polypeptid
WO2003078572A3 (en) Therapeutic polypeptides, nucleic acids encoding same and methods of use
WO2003040329A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
DE60139150D1 (de) Zusammensetzungen und verfahren zur therapie und diagnose von lungenkrebs
WO2001074897A3 (en) Protein amf-1 to amf-10 and nucleic acids encoding the same
DE60120507D1 (de) Menschliches leucinereiche wiederholungen enthaltendes protein, vorwiegend im dünndarm exprimiert, hlrrsi1
DK0811068T3 (da) Humane DNase I varianter
EP1390057A4 (de) Antikörper welche an antigene polypeptide binden, nukleinsäuren welche die antigene kodieren, und methode zur verwendung
ATE243760T1 (de) Verfahren zum nachweis und therapie von schuppenartigen zellkarzinomen und blasen- karzinomen insbesondere zur bestimmung der anwesenheit und behandlung von minimalen resterkrankungen, micrometastasierung oder der verbreitung von solchen karzinomtypen
WO2004089282A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use