ATE167060T1 - Epidermis-wachstumsfaktor als arzneimittel zur wiederherstellung der neuronen der substantia nigra in der behandlung nervenzerstörender störungen - Google Patents

Epidermis-wachstumsfaktor als arzneimittel zur wiederherstellung der neuronen der substantia nigra in der behandlung nervenzerstörender störungen

Info

Publication number: ATE167060T1
Authority: AT; Austria
Prior art keywords: treatment; growth factor; neurons; nerve; restoring
Prior art date: 1990-04-26

Application number

AT91106438T

Other languages

English (en)

Inventor

Angelo Carenzi

Gianni Pezzoli

Sante Ricciardi

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-26

Filing date

1991-04-22

Publication date

1998-06-15

1991-04-22 Application filed by Zambon Spa filed Critical Zambon Spa

1998-06-15 Application granted granted Critical

1998-06-15 Publication of ATE167060T1 publication Critical patent/ATE167060T1/de

Links

230000001066 destructive effect Effects 0.000 title 1
210000002615 epidermis Anatomy 0.000 title 1
239000003102 growth factor Substances 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
210000005036 nerve Anatomy 0.000 title 1
210000002569 neuron Anatomy 0.000 title 1
210000003523 substantia nigra Anatomy 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Zoology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT91106438T 1990-04-26 1991-04-22 Epidermis-wachstumsfaktor als arzneimittel zur wiederherstellung der neuronen der substantia nigra in der behandlung nervenzerstörender störungen ATE167060T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT20144A IT1240683B (it)	1990-04-26	1990-04-26	Composizione farmaceutica contenente egf

Publications (1)

Publication Number	Publication Date
ATE167060T1 true ATE167060T1 (de)	1998-06-15

Family

ID=11164158

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91106438T ATE167060T1 (de)	1990-04-26	1991-04-22	Epidermis-wachstumsfaktor als arzneimittel zur wiederherstellung der neuronen der substantia nigra in der behandlung nervenzerstörender störungen

Country Status (6)

Country	Link
US (1)	US5200396A (de)
EP (1)	EP0454026B1 (de)
AT (1)	ATE167060T1 (de)
DE (1)	DE69129563T2 (de)
ES (1)	ES2118726T3 (de)
IT (1)	IT1240683B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4237047A1 (en) *	1991-11-04	1993-05-06	I N R O Handels-Gmbh, 8750 Aschaffenburg, De	Drug contg. polypeptide homologous to nerve growth factor and slow virus sequence - for treating amyotrophic lateral sclerosis, spinal muscle atrophy or Parkinson's disease
FR2684301B1 (fr) *	1991-12-02	1995-03-24	Synthelabo	Composition pharmaceutique contenant de l'egf pour le traitement des pathologies bronchopulmonaires.
WO1994009371A1 (en) *	1992-10-09	1994-04-28	Massachusetts Institute Of Technology	Antemortem diagnostic test for alzheimer's disease
JP3952508B2 (ja) *	1993-11-09	2007-08-01	ニューロスフィアーズホウルディングスリミテッド	中枢神経系の幹細胞の原位置修飾及び操作
EP0743066A3 (de) *	1995-05-16	1998-09-30	Mitsui Pharmaceuticals, Inc.	Wundheilmittel
AU2002322264A1 (en) *	2001-06-14	2003-01-02	Bristol-Myers Squibb Company	Polynucleotide encoding a novel human growth factor with homology to epidermal growth factor, bgs-8, expressed highly in immune tissue
WO2004005520A1 (en) *	2002-07-03	2004-01-15	Nexgen Biotechnologies, Inc.	Method for preparing fusion polypeptide comprising epidermal growth factor and human serum albumin in plants
ES2304818B1 (es) *	2005-05-23	2009-10-26	Universidad Del Pais Vasco	Metodos para el diagnostico y pronostico de las enfermedades desmielinizantes y para el desarrollo de medicamentos contra las enfermedades desmielinizantes.
CN101897953B (zh) *	2009-05-27	2013-03-27	中国人民解放军军事医学科学院毒物药物研究所	无创性高穿透性表皮生长因子及其应用
WO2013166487A1 (en)	2012-05-04	2013-11-07	Yale University	Highly penetrative nanocarriers for treatment of cns disease
CN103204920A (zh) *	2013-04-28	2013-07-17	中国人民解放军军事医学科学院毒物药物研究所	一种新型表皮生长因子及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE38892B1 (en) *	1973-03-28	1978-06-21	Ici Ltd	Pharmaceutical compositions
WO1986002271A1 (en) *	1984-10-19	1986-04-24	Chiron Corporation	Promotion of wound healing with human epidermal growth factor prepared from recombinant dna
NZ222413A (en) *	1986-11-05	1991-06-25	Ethicon Inc	Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser
CA1322714C (en) *	1986-11-14	1993-10-05	Harry N. Antoniades	Wound healing and bone regeneration
US5057494A (en) *	1988-08-03	1991-10-15	Ethicon, Inc.	Method for preventing tissue damage after an ischemic episode
US5036046A (en) *	1988-10-12	1991-07-30	Eye Research Institute Of Retina Foundation, Inc.	Method for enhancing healing of corneal endothelial wounds
JPH04505319A (ja) *	1989-04-04	1992-09-17	アルコン　ラボラトリーズ　インコーポレイテッド	創傷、切傷および擦傷に対する治療剤のデリバリーとしてのリポソームの使用
JP3187410B2 (ja) *	1989-08-10	2001-07-11	住友製薬株式会社	脳内投与用徐放性製剤

1990
- 1990-04-26 IT IT20144A patent/IT1240683B/it active IP Right Grant
1991
- 1991-04-22 ES ES91106438T patent/ES2118726T3/es not_active Expired - Lifetime
- 1991-04-22 DE DE69129563T patent/DE69129563T2/de not_active Expired - Fee Related
- 1991-04-22 EP EP91106438A patent/EP0454026B1/de not_active Expired - Lifetime
- 1991-04-22 AT AT91106438T patent/ATE167060T1/de not_active IP Right Cessation
- 1991-04-24 US US07/690,670 patent/US5200396A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IT9020144A0 (it)	1990-04-26
EP0454026B1 (de)	1998-06-10
IT9020144A1 (it)	1991-10-26
IT1240683B (it)	1993-12-17
EP0454026A1 (de)	1991-10-30
DE69129563D1 (de)	1998-07-16
US5200396A (en)	1993-04-06
ES2118726T3 (es)	1998-10-01
DE69129563T2 (de)	1999-01-07

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Legal Events

Date	Code	Title	Description
1998-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties