ATE167859T1 - Antiproliferative 4h-naphtho(1,2-b)pyranderivate - Google Patents

Antiproliferative 4h-naphtho(1,2-b)pyranderivate

Info

Publication number: ATE167859T1
Authority: AT; Austria
Prior art keywords: alkyl; phenyl; optionally substituted; hydroxy; carboxy
Prior art date: 1991-10-09

Application number

AT92309169T

Other languages

English (en)

Inventor

Colin Peter Dell

Colin William Smith

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-09

Filing date

1992-10-08

Publication date

1998-07-15

1991-10-09 Priority claimed from GB919121358A external-priority patent/GB9121358D0/en

1992-06-19 Priority claimed from GB929213058A external-priority patent/GB9213058D0/en

1992-10-08 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1998-07-15 Application granted granted Critical

1998-07-15 Publication of ATE167859T1 publication Critical patent/ATE167859T1/de

Links

XGLHSMNFZCEVOV-UHFFFAOYSA-N 4h-benzo[h]chromene Chemical class C1=CC2=CC=CC=C2C2=C1CC=CO2 XGLHSMNFZCEVOV-UHFFFAOYSA-N 0.000 title 1
230000001028 anti-proliverative effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 8
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000004185 ester group Chemical group 0.000 abstract 2
125000001072 heteroaryl group Chemical group 0.000 abstract 2
125000001624 naphthyl group Chemical group 0.000 abstract 2
150000002825 nitriles Chemical class 0.000 abstract 2
-1 trifluoromethoxy, carboxy Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
125000004196 benzothienyl group Chemical group S1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Gastroenterology & Hepatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicinal Preparation (AREA)

AT92309169T 1991-10-09 1992-10-08 Antiproliferative 4h-naphtho(1,2-b)pyranderivate ATE167859T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919121358A GB9121358D0 (en)	1991-10-09	1991-10-09	Pharmaceutical compounds
GB929213058A GB9213058D0 (en)	1992-06-19	1992-06-19	Pharmaceutical compounds

Publications (1)

Publication Number	Publication Date
ATE167859T1 true ATE167859T1 (de)	1998-07-15

Family

ID=26299655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92309169T ATE167859T1 (de)	1991-10-09	1992-10-08	Antiproliferative 4h-naphtho(1,2-b)pyranderivate

Country Status (22)

Country	Link
US (1)	US5284868A (de)
EP (1)	EP0537949B1 (de)
JP (1)	JPH05194477A (de)
KR (1)	KR100228841B1 (de)
CN (1)	CN1034938C (de)
AT (1)	ATE167859T1 (de)
AU (1)	AU658003B2 (de)
CA (1)	CA2079428A1 (de)
CZ (1)	CZ281688B6 (de)
DE (1)	DE69226060T2 (de)
DK (1)	DK0537949T3 (de)
ES (1)	ES2117035T3 (de)
FI (1)	FI924551A7 (de)
HU (1)	HU218916B (de)
IL (1)	IL103356A (de)
MX (1)	MX9205714A (de)
MY (1)	MY111368A (de)
NO (1)	NO301587B1 (de)
NZ (1)	NZ244627A (de)
PH (1)	PH30659A (de)
RU (1)	RU2071472C1 (de)
TW (1)	TW221292B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9203497D0 (en) *	1992-02-19	1992-04-08	Lilly Industries Ltd	Pharmaceutical compounds
EP0599514A3 (en) *	1992-11-18	1994-07-06	Lilly Industries Ltd	Pyranoquinoline derivatives as inhibitors of cell proliferation.
GB9306062D0 (en) *	1993-03-24	1993-05-12	Lilly Industries Ltd	Pharmaceutical compounds
EP0619314A1 (de) *	1993-04-09	1994-10-12	Eli Lilly And Company	4-Phenyl-4H-Naphtho 2,1-b pyran Derivate und ihre Verwendung als Arzneimittel
WO1995008289A2 (en) *	1993-09-16	1995-03-30	Scimed Life Systems, Inc.	Percutaneous repair of cardiovascular anomalies and repair compositions
US5407955A (en) *	1994-02-18	1995-04-18	Eli Lilly And Company	Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease
US5665591A (en) *	1994-12-06	1997-09-09	Trustees Of Boston University	Regulation of smooth muscle cell proliferation
DE69734060T2 (de)	1996-05-24	2006-06-29	Angiotech Pharmaceuticals, Inc., Vancouver	Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege
IL119069A0 (en) *	1996-08-14	1996-11-14	Mor Research Applic Ltd	Pharmaceutical composition comprising tyrphostins
ATE260269T1 (de)	1999-11-05	2004-03-15	Cytovia Inc	Substituierte 4h-chromene und ähnliche verbindungen als kaspasis aktivatoren und apoptosis induktoren und deren verwendung
US6858607B1 (en)	2001-05-16	2005-02-22	Cytovia, Inc.	7,8-fused 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2002092594A1 (en) *	2001-05-16	2002-11-21	Cytovia, Inc.	Substituted 4h-chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2002092076A1 (en) *	2001-05-16	2002-11-21	Cytovia, Inc.	Substituted coumarins and quinolines as caspases activators
CN100349887C (zh) *	2002-05-16	2007-11-21	西托维亚公司	取代的4－芳基－4h－吡咯并[2,3－h]色烯和类似物及其药物组合物和用途
EP1513515A2 (de) *	2002-05-16	2005-03-16	Cytovia, Inc.	Substitutierte 4h-chromene, 2h-chromene, chromane und analoga als aktivatoren von caspasen und induktoren von apoptose und ihre verwendung
US20040127511A1 (en) *	2002-12-12	2004-07-01	Pharmacia Corporation	Tricyclic aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2
US20040127519A1 (en) *	2002-12-12	2004-07-01	Pharmacia Corporation	Method of using aminocyanopyridine compounds as mitogen activated protein kinase-activated protein kinase-2 inhibitors
ES2403340T3 (es) *	2004-09-09	2013-05-17	Howard Florey Institute Of Experimental Physiology And Medicine	Inhibidores de aminopeptidasa regulada por insulina (IRAP) y usos de los mismos
CN101119726B (zh) *	2005-02-16	2011-02-02	麦仁斯有限公司	用于治疗或预防涉及肥胖、糖尿病、代谢综合症、神经变性疾病和线粒体功能障碍疾病的疾病的药物组合物
US20080183282A1 (en) *	2006-03-09	2008-07-31	Saul Yedgar	Use of lipid conjugates for the coating of stents and catheters
EP2262797A4 (de)	2007-11-19	2011-11-30	Howard Florey Inst	Inhibitoren der insulinregulierten aminopeptidase (irap) und anwendungen davon
EA015364B1 (ru) *	2009-03-18	2011-06-30	Учреждение Российской Академии Наук Институт Элементоорганических Соединений Им. А.Н. Несмеянова Ран (Инэос Ран)	6,6'-диизопропил-8,8'-диметил-2,2'-динитро-3,3'-бис(трифторметил)- 3н,3'н-[9,9']ди[бензо(f)хроменил]-5,10,5',10'-тетраол, обладающий противоопухолевой и противогрибковой активностью, и способ его получения
US9371333B2 (en)	2010-11-12	2016-06-21	Deutsches Krebsforschungszentrum	Chromene derivatives and their analoga as Wnt pathway antagonists
US20140275174A1 (en)	2011-11-10	2014-09-18	Memorial Sloan-Kettering Cancer Center	TREATMENT OF OVARIAN CANCER WITH 2-AMINO-4H-NAPHTHO[1,2-b]PYRAN-3-CARBONITRILES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU724509A1 (ru) *	1978-09-21	1980-03-30	Пермский государственный фармацевтический институт	Способ получени 2-ароил-3н- нафто 2,1-в пиранонов-3
EP0412160A4 (en) *	1988-04-14	1991-09-11	Yamanouchi Pharmaceutical Co. Ltd.	Substance q-2819 and process for its preparation

1992
- 1992-09-25 US US07/951,629 patent/US5284868A/en not_active Expired - Fee Related
- 1992-09-29 CA CA002079428A patent/CA2079428A1/en not_active Abandoned
- 1992-10-05 IL IL103356A patent/IL103356A/en not_active IP Right Cessation
- 1992-10-05 AU AU26216/92A patent/AU658003B2/en not_active Ceased
- 1992-10-05 PH PH45043A patent/PH30659A/en unknown
- 1992-10-05 TW TW081107894A patent/TW221292B/zh active
- 1992-10-05 CZ CS923035A patent/CZ281688B6/cs not_active IP Right Cessation
- 1992-10-06 NZ NZ244627A patent/NZ244627A/en unknown
- 1992-10-06 MX MX9205714A patent/MX9205714A/es not_active IP Right Cessation
- 1992-10-06 RU SU925052861A patent/RU2071472C1/ru active
- 1992-10-07 KR KR1019920018309A patent/KR100228841B1/ko not_active Expired - Fee Related
- 1992-10-07 MY MYPI92001807A patent/MY111368A/en unknown
- 1992-10-08 AT AT92309169T patent/ATE167859T1/de not_active IP Right Cessation
- 1992-10-08 CN CN92111625A patent/CN1034938C/zh not_active Expired - Fee Related
- 1992-10-08 HU HU9203183A patent/HU218916B/hu not_active IP Right Cessation
- 1992-10-08 EP EP92309169A patent/EP0537949B1/de not_active Expired - Lifetime
- 1992-10-08 JP JP4269002A patent/JPH05194477A/ja active Pending
- 1992-10-08 ES ES92309169T patent/ES2117035T3/es not_active Expired - Lifetime
- 1992-10-08 DK DK92309169T patent/DK0537949T3/da active
- 1992-10-08 DE DE69226060T patent/DE69226060T2/de not_active Expired - Fee Related
- 1992-10-08 NO NO923910A patent/NO301587B1/no not_active IP Right Cessation
- 1992-10-08 FI FI924551A patent/FI924551A7/fi unknown

Also Published As

Publication number	Publication date
CA2079428A1 (en)	1993-04-10
CZ281688B6 (cs)	1996-12-11
TW221292B (de)	1994-02-21
CZ303592A3 (en)	1993-12-15
HU218916B (hu)	2000-12-28
JPH05194477A (ja)	1993-08-03
PH30659A (en)	1997-09-16
HUT62281A (en)	1993-04-28
AU658003B2 (en)	1995-03-30
MX9205714A (es)	1993-04-01
HU9203183D0 (en)	1992-12-28
DE69226060D1 (de)	1998-08-06
KR930007931A (ko)	1993-05-20
EP0537949A1 (de)	1993-04-21
FI924551A0 (fi)	1992-10-08
AU2621692A (en)	1993-04-22
NO923910D0 (no)	1992-10-08
DK0537949T3 (da)	1999-02-15
FI924551A7 (fi)	1993-04-10
US5284868A (en)	1994-02-08
NO301587B1 (no)	1997-11-17
RU2071472C1 (ru)	1997-01-10
NO923910L (no)	1993-04-13
CN1073437A (zh)	1993-06-23
CN1034938C (zh)	1997-05-21
NZ244627A (en)	1994-12-22
MY111368A (en)	1999-12-31
ES2117035T3 (es)	1998-08-01
DE69226060T2 (de)	1998-11-19
EP0537949B1 (de)	1998-07-01
IL103356A (en)	1998-02-22
KR100228841B1 (ko)	1999-11-01
IL103356A0 (en)	1993-03-15

Legal Events

Date	Code	Title	Description
1999-03-15	UEP	Publication of translation of european patent specification
2003-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE167859T1 (de)	1998-07-15	Antiproliferative 4h-naphtho(1,2-b)pyranderivate
CO5150224A1 (es)	2002-04-29	Compuestos de triazol y su utilizacion
BR0316241A (pt)	2005-10-04	Pirrolobenzodiazepinas
NO983099L (no)	1995-02-13	Nye retrovirale proteasehemmere
DK1221440T3 (da)	2007-09-17	Benzoheterocykliske derivater der er nyttige som vasopressin- eller oxytocinmodulatorer
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
BR9103433A (pt)	1992-05-19	Derivados de 4-benzil-isoxazol
DK0641325T3 (da)	2001-04-17	Inhibitorer af retroviral protease
DE69631865D1 (de)	2004-04-22	Sulfonamide mit Elastase inhibierender Wirkung
ATE204576T1 (de)	2001-09-15	Methotrexat-derivate
NO982297D0 (no)	1998-05-20	Substituerte aminocycloalkylpyrrolidin-derivater
ES2130258T3 (es)	1999-07-01	Compuesto amino terciario sustituido o sal de este compuesto.
MY109777A (en)	1997-06-30	Pharmaceutical compounds therewith
FI911138A0 (fi)	1991-03-07	Ny substituerad aminfoerening och foerfarande foer dess framstaellning.
DE69113893D1 (de)	1995-11-23	6,7-Disubstituierte 2-Aminotetraline als Immunomodulatoren und pharmazeutische Zusammensetzungen davon.
ATE145395T1 (de)	1996-12-15	5-amino-2-phenoxysulfonanilid-derivate
TH17774A (th)	1996-02-21	อนุพันธ์ 1,3-ออกซาซิน-4-โอนชนิดใหม่ สารฆ่าวัชพืชที่มีอนุพันธ์เหล่านี้และสารมัธยันตร์สำหรับการเตรียอนุพันธ์เหล่านี้
MX9204939A (es)	1993-03-01	Inhibidores 5-bis-aminometilen-1,3-dioxan-4,6-diona n,n',n'-trisubstituidas, de la acil coenzima a: colesterol-aciltransferasa.
DE69017763D1 (de)	1995-04-20	Angolamycin-Derivate.
ATE154243T1 (de)	1997-06-15	Hemmstoff der blutgefässhypertrophie
ATE159253T1 (de)	1997-11-15	2-thiazolylpyrroleakrylate mit fungizider wirkung
TH6968A (th)	1989-12-01	ไตรสับสทิทิวด์ 1,3,5-ไตรเอซีน 2,4,6-ไตรโอน