ATE169027T1 - Herstellung von fluoro-nukleosiden und dafür geeignete zwischenprodukte - Google Patents

Herstellung von fluoro-nukleosiden und dafür geeignete zwischenprodukte

Info

Publication number: ATE169027T1
Authority: AT; Austria
Prior art keywords: pct; fluoronucleosides; production; intermediate products; suitable intermediate
Prior art date: 1993-05-12

Application number

AT94914519T

Other languages

English (en)

Inventor

Owen Ross Chambers

Patrick Charles Youmans

Andrew Lawrence Germain

Original Assignee

Rhodia Limited

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-12

Filing date

1994-05-12

Publication date

1998-08-15

1993-05-12 Priority claimed from GB939309794A external-priority patent/GB9309794D0/en

1994-05-12 Application filed by Rhodia Limited, Wellcome Found filed Critical Rhodia Limited

1998-08-15 Application granted granted Critical

1998-08-15 Publication of ATE169027T1 publication Critical patent/ATE169027T1/de

Links

239000013067 intermediate product Substances 0.000 title 1
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
UMDFLFHAXYPYQN-UKTARXLSSA-N anhydro nucleoside Chemical compound C([C@H]1O[C@H]2N3C=C(C(N=C3O[C@@H]1[C@@H]2F)=O)C)OC(=O)C1=CC=CC=C1 UMDFLFHAXYPYQN-UKTARXLSSA-N 0.000 abstract 1
229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT94914519T 1993-05-12 1994-05-12 Herstellung von fluoro-nukleosiden und dafür geeignete zwischenprodukte ATE169027T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939309794A GB9309794D0 (en)	1993-05-12	1993-05-12	Preparation of flouro-nucleosides
GB939318914A GB9318914D0 (en)	1993-05-12	1993-09-13	Preparation of fluoro-nucleosides and intermediates for use therein

Publications (1)

Publication Number	Publication Date
ATE169027T1 true ATE169027T1 (de)	1998-08-15

Family

ID=26302888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94914519T ATE169027T1 (de)	1993-05-12	1994-05-12	Herstellung von fluoro-nukleosiden und dafür geeignete zwischenprodukte

Country Status (8)

Country	Link
US (1)	US5717086A (de)
EP (1)	EP0698032B1 (de)
JP (1)	JPH08510228A (de)
AT (1)	ATE169027T1 (de)
AU (1)	AU6686394A (de)
DE (1)	DE69412090T2 (de)
ES (1)	ES2121204T3 (de)
WO (1)	WO1994026762A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6057197A (en) *	1998-05-20	2000-05-02	Mosel Vitelic, Inc.	Isolation scheme to prevent field oxide edge from oxide loss
US7160537B2 (en) *	2003-12-15	2007-01-09	Siemens Medical Solutions Usa, Inc.	Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) *	2003-12-15	2005-06-16	Cti Pet Systems, Inc.	Method for preparing radiolabeled thymidine
GB0608876D0 (en)	2006-05-05	2006-06-14	Medivir Ab	Combination therapy
FR2946981A1 (fr) *	2009-06-19	2010-12-24	Bluestar Silicones France	Composition silicone reticulable par deshydrogenocondensation en presence d'un catalyseur metallique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5223263A (en) *	1988-07-07	1993-06-29	Vical, Inc.	Liponucleotide-containing liposomes
US5153180A (en) *	1986-07-24	1992-10-06	Eckart Matthes	Fluorinated nucleosides and process for treating retrovirus infections therewith
GB8719877D0 (en) *	1987-08-22	1987-09-30	Wellcome Found	Antiviral compounds
GB8726136D0 (en) *	1987-11-07	1987-12-09	Wellcome Found	Therapeutic nucleosides
HU198949B (en) *	1987-12-30	1989-12-28	Mta Koezponti Kemiai Kutato In	Process for producing 5-substituted-3'azido-2',3'-dideoxyribonucleosides
US5157114A (en) *	1988-08-19	1992-10-20	Burroughs Wellcome Co.	2',3'-dideoxy-3'-fluoro-5-ethyngluridine
JPH0296590A (ja) *	1988-09-30	1990-04-09	Asahi Glass Co Ltd	新規核酸類
US5449664A (en) *	1988-11-21	1995-09-12	Syntex (U.S.A.) Inc.	Antiviral agents
CA2073063A1 (en) *	1989-11-06	1991-05-07	Jo Klaveness	Nucleoside derivatives
DK0470355T3 (da) *	1990-08-06	1996-07-15	American Cyanamid Co	Fremgangsmåde til fremstilling af deoxynucleosider
IL100480A0 (en) *	1991-01-15	1992-09-06	American Cyanamid Co	Process for the preparation of 3'-fluoropyrimidine nucleosides

1994
- 1994-05-12 ES ES94914519T patent/ES2121204T3/es not_active Expired - Lifetime
- 1994-05-12 EP EP94914519A patent/EP0698032B1/de not_active Expired - Lifetime
- 1994-05-12 JP JP6525157A patent/JPH08510228A/ja active Pending
- 1994-05-12 AT AT94914519T patent/ATE169027T1/de not_active IP Right Cessation
- 1994-05-12 US US08/545,842 patent/US5717086A/en not_active Expired - Fee Related
- 1994-05-12 WO PCT/GB1994/001024 patent/WO1994026762A1/en not_active Ceased
- 1994-05-12 AU AU66863/94A patent/AU6686394A/en not_active Abandoned
- 1994-05-12 DE DE69412090T patent/DE69412090T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69412090T2 (de)	1999-01-07
ES2121204T3 (es)	1998-11-16
EP0698032B1 (de)	1998-07-29
JPH08510228A (ja)	1996-10-29
DE69412090D1 (de)	1998-09-03
US5717086A (en)	1998-02-10
AU6686394A (en)	1994-12-12
EP0698032A1 (de)	1996-02-28
WO1994026762A1 (en)	1994-11-24

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Legal Events

Date	Code	Title	Description
1999-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties