ATE169677T1 - Neue neutrophilaktivierende faktoren - Google Patents
Neue neutrophilaktivierende faktorenInfo
- Publication number
- ATE169677T1 ATE169677T1 AT92309407T AT92309407T ATE169677T1 AT E169677 T1 ATE169677 T1 AT E169677T1 AT 92309407 T AT92309407 T AT 92309407T AT 92309407 T AT92309407 T AT 92309407T AT E169677 T1 ATE169677 T1 AT E169677T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- inhibitors
- activating factors
- neutrophil activating
- ena
- Prior art date
Links
- 210000000440 neutrophil Anatomy 0.000 title abstract 3
- 230000003213 activating effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 102100036150 C-X-C motif chemokine 5 Human genes 0.000 abstract 2
- 101000947186 Homo sapiens C-X-C motif chemokine 5 Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 208000019693 Lung disease Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/778,413 US5401651A (en) | 1991-10-16 | 1991-10-16 | DNA encoding ENA-78, a neutrophil activating factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE169677T1 true ATE169677T1 (de) | 1998-08-15 |
Family
ID=25113266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92309407T ATE169677T1 (de) | 1991-10-16 | 1992-10-15 | Neue neutrophilaktivierende faktoren |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5401651A (de) |
| EP (1) | EP0538030B1 (de) |
| JP (1) | JPH05331196A (de) |
| AT (1) | ATE169677T1 (de) |
| AU (1) | AU660192B2 (de) |
| CA (1) | CA2080525A1 (de) |
| DE (1) | DE69226592T2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174995B1 (en) | 1994-08-23 | 2001-01-16 | Haodong Li | Human chemokines, CKβ4 and CKβ10/MCP-4 |
| US6458349B1 (en) | 1995-06-02 | 2002-10-01 | Human Genome Sciences, Inc. | Chemokine β-4 polypeptides |
| US6391589B1 (en) | 1994-08-23 | 2002-05-21 | Human Genome Sciences, Inc. | Human chemokine beta-10 mutant polypeptides |
| US5627156A (en) * | 1994-09-23 | 1997-05-06 | University Of Nebraska Board Of Regents | Polypeptide agonists for human interleukin-8 |
| US6410268B1 (en) * | 1996-03-18 | 2002-06-25 | Human Genome Sciences, Inc. | Polynucleotides encoding chemokine alpha-3 |
| US6290948B1 (en) * | 1996-05-14 | 2001-09-18 | Smithkline Beecham Corporation | Method of treating sepsis and ARDS using chamohine beta-10 |
| AU731926B2 (en) * | 1997-01-17 | 2001-04-05 | Johnson & Johnson Medical Limited | Peptides for use in wound treatment |
| EP0858808B1 (de) * | 1997-01-17 | 2003-04-02 | Johnson & Johnson Medical Ltd. | Peptide zur Verwendung in Wundbehandlung |
| US6989435B2 (en) | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US7067117B1 (en) | 1997-09-11 | 2006-06-27 | Cambridge University Technical Services, Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US20020034819A1 (en) * | 1998-02-23 | 2002-03-21 | Alan K. Smith | Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses |
| CA2305787A1 (en) * | 2000-05-09 | 2001-11-09 | The University Of British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
| CA2245224A1 (en) * | 1998-08-14 | 2000-02-14 | Jiang-Hong Giong | Chemokine receptor antagonists and chemotherapeutics |
| JP2002506830A (ja) * | 1998-03-13 | 2002-03-05 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 治療的ケモカイン受容体アンタゴニスト |
| US7238711B1 (en) | 1999-03-17 | 2007-07-03 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| CA2402238C (en) * | 2000-03-07 | 2011-12-13 | Japan Tobacco Inc. | Polypeptides having neutrophil stimulating activity |
| US20060233748A1 (en) * | 2002-09-13 | 2006-10-19 | Ahmed Merzouk | Mimetics of interleukin-8 and methods of using them in the prevention, treatment, diagnosis, and ameliorization of symptoms of a disease |
| US20050059584A1 (en) * | 2002-08-16 | 2005-03-17 | Ahmed Merzouk | Novel chemokine mimetics synthesis and their use |
| US7378098B2 (en) * | 2000-04-12 | 2008-05-27 | The University Of British Columbia | CXC chemokine receptor 4 agonist peptides |
| US7091310B2 (en) * | 2002-09-13 | 2006-08-15 | Chemokine Therapeutics Corporation | Chemokine analogs for the treatment of human disease |
| US20070116669A1 (en) * | 2002-09-13 | 2007-05-24 | Chemokine Therapeutics Corporation | Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases |
| US7368425B2 (en) * | 2006-03-24 | 2008-05-06 | Chemokine Therapeutics Corp. | Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis |
| US6962971B2 (en) * | 2001-03-16 | 2005-11-08 | The Regents Of The University Of California | Chemokines and methods for inducing the differentiation of fibroblasts to myofibroblasts |
| ATE518884T1 (de) | 2002-05-01 | 2011-08-15 | Human Genome Sciences Inc | Spezifisch an chemokin beta-4 bindende antikörper |
| SG191716A1 (en) | 2010-11-19 | 2013-08-30 | Toshio Imai | Neutralizing anti-ccl20 antibodies |
| CN103376228B (zh) * | 2012-04-27 | 2016-02-17 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种检测或辅助检测放射性肺纤维化的试剂盒 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3133305B2 (ja) * | 1987-11-19 | 2001-02-05 | ノバルティス・アクチエンゲゼルシャフト | 好中球活性化因子 |
-
1991
- 1991-10-16 US US07/778,413 patent/US5401651A/en not_active Expired - Fee Related
-
1992
- 1992-10-14 CA CA002080525A patent/CA2080525A1/en not_active Abandoned
- 1992-10-15 AU AU27069/92A patent/AU660192B2/en not_active Ceased
- 1992-10-15 AT AT92309407T patent/ATE169677T1/de active
- 1992-10-15 EP EP92309407A patent/EP0538030B1/de not_active Expired - Lifetime
- 1992-10-15 DE DE69226592T patent/DE69226592T2/de not_active Expired - Fee Related
- 1992-10-16 JP JP4279035A patent/JPH05331196A/ja active Pending
-
1994
- 1994-11-15 US US08/340,102 patent/US5591718A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0538030B1 (de) | 1998-08-12 |
| DE69226592T2 (de) | 1999-03-04 |
| CA2080525A1 (en) | 1993-04-17 |
| EP0538030A3 (de) | 1994-05-04 |
| US5591718A (en) | 1997-01-07 |
| EP0538030A2 (de) | 1993-04-21 |
| DE69226592D1 (de) | 1998-09-17 |
| AU2706992A (en) | 1993-04-22 |
| AU660192B2 (en) | 1995-06-15 |
| JPH05331196A (ja) | 1993-12-14 |
| US5401651A (en) | 1995-03-28 |
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