ATE170512T1 - Verbesserte methode zur herstellung von 4-alkyl-3-amino-2-chlor-pyridinen - Google Patents
Verbesserte methode zur herstellung von 4-alkyl-3-amino-2-chlor-pyridinenInfo
- Publication number
- ATE170512T1 ATE170512T1 AT93118542T AT93118542T ATE170512T1 AT E170512 T1 ATE170512 T1 AT E170512T1 AT 93118542 T AT93118542 T AT 93118542T AT 93118542 T AT93118542 T AT 93118542T AT E170512 T1 ATE170512 T1 AT E170512T1
- Authority
- AT
- Austria
- Prior art keywords
- amino
- pyridines
- chlorine
- alkyl
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- DNPUCFVFVQRIAQ-UHFFFAOYSA-N 6,11-dihydro-5h-dipyrido[3,2-a:3',2'-e][1,4]diazepine Chemical class C1NC2=CC=CN=C2NC2=NC=CC=C12 DNPUCFVFVQRIAQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97796292A | 1992-11-18 | 1992-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE170512T1 true ATE170512T1 (de) | 1998-09-15 |
Family
ID=25525683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93118542T ATE170512T1 (de) | 1992-11-18 | 1993-11-18 | Verbesserte methode zur herstellung von 4-alkyl-3-amino-2-chlor-pyridinen |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0598396B1 (de) |
| AT (1) | ATE170512T1 (de) |
| DE (1) | DE69320759T2 (de) |
| DK (1) | DK0598396T3 (de) |
| ES (1) | ES2121916T3 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4333697A1 (de) * | 1993-10-02 | 1995-04-06 | Merck Patent Gmbh | Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen |
| AR015104A1 (es) * | 1996-11-13 | 2001-04-18 | Dowelanco | Compuestos de n-arilsulfilimina sustituidos, utiles como catalizadores en la preparacion de compuestos de n-arilarilsulfonamida; proceso para preparar dichos compuestos y su uso para catalizar dicha preparacion. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172095A (en) * | 1977-06-10 | 1979-10-23 | Schering Corporation | Novel synthesis of 3-amino-2-methylbenzotrifluoride and the intermediates thereof |
| US4496765A (en) * | 1983-09-07 | 1985-01-29 | Monsanto Company | Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride |
| US4480130A (en) * | 1983-09-07 | 1984-10-30 | Monsanto Company | Preparation of ortho-(alkylthiomethyl) anilines by catalytic sulfilimine rearrangement |
| CA2030056C (en) * | 1989-11-17 | 1995-10-17 | Karl D. Hargrave | 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection |
| US5200522A (en) * | 1991-06-11 | 1993-04-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for preparing 3-amino-2-chloro-4-alkylpyridines |
| WO1992022531A1 (en) * | 1991-06-11 | 1992-12-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines |
-
1993
- 1993-11-18 DK DK93118542T patent/DK0598396T3/da active
- 1993-11-18 ES ES93118542T patent/ES2121916T3/es not_active Expired - Lifetime
- 1993-11-18 DE DE69320759T patent/DE69320759T2/de not_active Expired - Fee Related
- 1993-11-18 AT AT93118542T patent/ATE170512T1/de not_active IP Right Cessation
- 1993-11-18 EP EP93118542A patent/EP0598396B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69320759D1 (de) | 1998-10-08 |
| DK0598396T3 (da) | 1998-11-23 |
| DE69320759T2 (de) | 1999-03-25 |
| ES2121916T3 (es) | 1998-12-16 |
| EP0598396B1 (de) | 1998-09-02 |
| EP0598396A1 (de) | 1994-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |