ATE170528T1 - Sialsäurederivate - Google Patents

Sialsäurederivate

Info

Publication number: ATE170528T1
Authority: AT; Austria
Prior art keywords: acid derivatives; sialic acid; anomer; acetyl; hydrogen
Prior art date: 1991-03-06

Application number

AT92810176T

Other languages

English (en)

Inventor

Kaoru Okamoto

Shinji Morita

Original Assignee

Nippon Zoki Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-06

Filing date

1992-03-06

Publication date

1998-09-15

1992-03-06 Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co

1998-09-15 Application granted granted Critical

1998-09-15 Publication of ATE170528T1 publication Critical patent/ATE170528T1/de

Links

SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title abstract 3
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
230000002093 peripheral effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT92810176T 1991-03-06 1992-03-06 Sialsäurederivate ATE170528T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP6801791		1991-03-06

Publications (1)

Publication Number	Publication Date
ATE170528T1 true ATE170528T1 (de)	1998-09-15

Family

ID=13361639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92810176T ATE170528T1 (de)	1991-03-06	1992-03-06	Sialsäurederivate

Country Status (4)

Country	Link
US (1)	US5438125A (de)
EP (1)	EP0502827B1 (de)
AT (1)	ATE170528T1 (de)
DE (1)	DE69226798T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5489675A (en) *	1992-06-25	1996-02-06	E. I. Du Pont De Nemours And Company	Disaccharide sialidase substrates and inhibitors
US5783564A (en) *	1993-12-24	1998-07-21	Mitsubishi Chemical Corporation	Sialic acid derivatives
TW479061B (en) *	1993-12-24	2002-03-11	Mitsubishi Chem Corp	Sialic acid derivatives
US6066323A (en) *	1994-02-02	2000-05-23	The United States Of America As Represented By The Secretary Of The Army	Use of antibodies to sialidase as anti-infectious agents and anti-inflammatory agents
ES2169223T3 (es) *	1996-02-08	2002-07-01	Ngk Insulators Ltd	Substancia anticancerosa que inhibe la metastasis cancerosa.
JP4005115B1 (ja) *	2007-02-08	2007-11-07	日本臓器製薬株式会社	疼痛疾患治療剤
US9119866B2 (en) *	2008-04-08	2015-09-01	Huiru Wang	Glycan-based drugs, therapies and biomarkers
JP5626734B2 (ja) *	2009-05-15	2014-11-19	公益財団法人ヒューマンサイエンス振興財団	Ｇｎｅタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物
CN112175103B (zh) *	2020-10-29	2022-07-15	绍兴文理学院	一种含有聚唾液酸基团的聚甘油脂肪酸酯衍生物及其合成方法和其在药物制剂中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3219209A1 (de) *	1981-05-22	1982-12-09	Kanto Ishi Pharmaceutical Co., Ltd., Tokyo	N-acetylneuraminsaeure-derivate
JPS60190791A (ja) *	1984-03-09	1985-09-28	Kanto Ishi Pharma Co Ltd	シアル酸誘導体およびその製造法
JPS62221694A (ja) *	1986-03-20	1987-09-29	Kazuo Achinami	シアロ−ホスホリル−グルコサミン誘導体及びその製造方法
AU594468B2 (en) *	1986-05-12	1990-03-08	Mect Corporation	Sialosylcholesterol, process for its preparation, and drug for treating diseases of nervous system
JPH07100709B2 (ja) *	1986-06-11	1995-11-01	日本臓器製薬株式会社	新規グリコシル化法
US5037969A (en) *	1986-07-03	1991-08-06	Takeda Chemical Industries, Ltd.	Glycosyl derivatives and use thereof
US4990603A (en) *	1986-07-04	1991-02-05	Mect Corporation	Sialic acid derivatives and process therefor
JPS6344590A (ja) *	1986-08-12	1988-02-25	Mect Corp	シアル酸誘導体の製造方法
US5034516A (en) *	1987-08-04	1991-07-23	University Of Ottawa	Synthetic antigens of sialic acid and derivatives thereof
JPS6461493A (en) *	1987-08-28	1989-03-08	Kanto Ishi Pharma Co Ltd	Production of sialosylceramides
JPH01125394A (ja) *	1987-11-10	1989-05-17	Mect Corp	シアロシルグリセロリピッド類及びその製造方法
JPH01228997A (ja) *	1988-03-10	1989-09-12	Mect Corp	シアロシルグリセライド類及びその製造方法
JPH02145596A (ja) *	1988-11-29	1990-06-05	Mect Corp	活性エステル基を持つシタル酸誘導体
JPH02202895A (ja) *	1989-02-01	1990-08-10	Mect Corp	非天然型シアロシルセラミド類及びその製造方法
JPH02209885A (ja) *	1989-02-08	1990-08-21	Mect Corp	アミド結合したシアロシルグリセロリピッド

1992
- 1992-03-04 US US07/845,665 patent/US5438125A/en not_active Expired - Fee Related
- 1992-03-06 EP EP92810176A patent/EP0502827B1/de not_active Expired - Lifetime
- 1992-03-06 AT AT92810176T patent/ATE170528T1/de not_active IP Right Cessation
- 1992-03-06 DE DE69226798T patent/DE69226798T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0502827B1 (de)	1998-09-02
DE69226798T2 (de)	1999-04-15
US5438125A (en)	1995-08-01
EP0502827A1 (de)	1992-09-09
DE69226798D1 (de)	1998-10-08

Legal Events

Date	Code	Title	Description
1999-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE157346T1 (de)	1997-09-15	Hexahydronapththalinesterderivate, ihre herstellung und ihre therapeutischen verwendungen
GR3033020T3 (en)	2000-08-31	Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses.
NO934536D0 (no)	1993-12-10	Fenoksy- og fenoksyalkyl-pepiridiner som antivirale midler
AU591640B2 (en)	1989-12-14	Quinolonecarboxylic acid derivatives
HU9301155D0 (en)	1993-07-28	Methods for producing steroide derivatives and for their application in medical treatment
NO953052D0 (no)	1995-08-03	Nye pyrrolokarbazoler
DE69226798D1 (de)	1998-10-08	Sialsäurederivate
DE69227088D1 (de)	1998-10-29	Verwendung von 1-(aminoalkyl)-3-Quinoxalin-2-on Derivaten zur Herstellung von neuroprotektiven Mitteln
IE890177L (en)	1989-07-21	Piperidinyl derivatives
HUT54362A (en)	1991-02-28	Process for producing cumarin derivatives and pharmaceutical compositions containing them
ATE174324T1 (de)	1998-12-15	Hexahydronaphthalenesterderivate, ihre herstellung und ihre therapeutischen anwendungen
HUT75647A (en)	1997-05-28	Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
DK0570850T3 (da)	1997-06-16	Benzo(b)thiophen-3-yl-piperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
GR3006108T3 (de)	1993-06-21
FI883507A0 (fi)	1988-07-26	Naftotiazepinderivat och deras framstaellning.
ATE160567T1 (de)	1997-12-15	Psoralen-derivate, deren herstellung und verwendung als arzneimittel